Production Method 1

601517-02-6

944742-29-4

Reaction Conditions

1.1 Catalysts: Sulfuric acid Solvents: Water ;  3 h, 100 °C; 100 °C → rt
1.2 Solvents: Water ;  pH 5 - 6, 0 °C

Reference

Quinazoline derivatives as antitumor agents and their preparation

, World Intellectual Property Organization, , ,

Production Method 2

601517-02-6

944742-29-4

Reaction Conditions

1.1 Catalysts: Sulfuric acid Solvents: Water ;  20 min, rt; 5 h, 100 °C; 100 °C → rt
1.2 Reagents: Water ;  cooled

Reference

Preparation of piperidinylmethoxyquinazolinylaminopyrazolylacetamides as aurora kinase inhibitors.

, World Intellectual Property Organization, , ,

Production Method 3

601517-02-6

944742-29-4

Reaction Conditions

1.1 Reagents: Sulfuric acid ;  rt; 1 h, 100 °C

Reference

Preparation of cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use

, World Intellectual Property Organization, , ,

Production Method 4

601517-02-6

944742-29-4

Reaction Conditions

1.1 Reagents: Sulfuric acid ;  1 h, 100 °C

Reference

Aminodihydrothiazine and aminodioxidodihydrothiazine compounds as beta-secretase antagonists and their preparation

, World Intellectual Property Organization, , ,

Production Method 5

601517-02-6

944742-29-4

Reaction Conditions

1.1 Reagents: Sulfuric acid ;  rt; 1 h, 100 °C

Reference

Cyclopropathiazin-2-amine compounds as beta-secretase inhibitors and their preparation

, World Intellectual Property Organization, , ,

Production Method 6

601517-02-6

944742-29-4

Reaction Conditions

1.1 Reagents: Sulfuric acid ;  rt; 1 h, 100 °C

Reference

Bridged bicyclic aminothiazine dioxide compounds as inhibitors of beta-secretase and their preparation

, World Intellectual Property Organization, , ,

Production Method 7

601517-02-6

944742-29-4

Reaction Conditions

1.1 Reagents: Sulfuric acid Solvents: Water ;  rt; 1 h, 100 °C

Reference

Preparation of perfluorinated 5,6-dihydro-4H-1,3-oxazin-2-amine compounds as β-secretase inhibitors and methods of use

, World Intellectual Property Organization, , ,

Production Method 8

601517-02-6

944742-29-4

Reaction Conditions

1.1 Reagents: Sulfuric acid Solvents: Formic acid ;  1 h, 100 °C; 100 °C → rt
1.2 Reagents: Water ;  cooled

Reference

Fused multi-cyclic sulfone compounds as inhibitors of beta-secretase and methods of use and preparation thereof

, United States, , ,

5-Fluoro-7-methoxyquinazolin-4(3H)-one Raw materials

• 2-Amino-6-fluoro-4-methoxy-benzonitrile

5-Fluoro-7-methoxyquinazolin-4(3H)-one Preparation Products

• 5-Fluoro-7-methoxyquinazolin-4(3H)-one (944742-29-4)

• 1. Examination of deposit in commercial diluted phosphoric acid
  Analyst, 1880,5, 146-147
• 2. Excellent lithium ion storage property of porous MnCo2O4 nanorods?
  Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
• 3. Evolution of shape, size, and areal density of a single plane of Si nanocrystals embedded in SiO2 matrix studied by atom probe tomography
  Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
• 4. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 5. Emerging investigators
  Polym. Chem., 2015,6, 5501-5502

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