Production Method 1

53663-39-1

944268-58-0

Reaction Conditions

1.1 Solvents: Diethyl ether ;  0 °C; 0 °C → rt; overnight, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  cooled

Reference

Enantioselective Bromo-oxycyclization of Silanol

Xia, Zilei; Hu, Jiadong; Shen, Zhigao; Wan, Xiaolong; Yao, Qizheng; et al, Organic Letters, 2016, 18(1), 80-83

Production Method 2

53663-39-1

944268-58-0

Reaction Conditions

1.1 Reagents: Oxalyl chloride Catalysts: Dimethylformamide Solvents: Dichloromethane ;  0 °C; 0 °C → rt; 2 h, rt
1.2 Catalysts: Cuprous iodide Solvents: Diethyl ether ,  Tetrahydrofuran ;  rt → -78 °C; -78 °C → rt; 2 h, rt

Reference

Construction of axial chirality via palladium/chiral norbornene cooperative catalysis

Liu, Ze-Shui; Hua, Yu; Gao, Qianwen; Ma, Yuanyuan; Tang, Hua; et al, Nature Catalysis, 2020, 3(9), 727-733

Production Method 3

676-58-4

109179-31-9

944268-58-0

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  0 °C

Reference

Annulative Morita-Baylis-Hillman reaction to synthesise chiral dibenzocycloheptanes

Mondal, Atanu; Shivangi; Tung, Pinku; Wagulde, Siddhant V.; Ramasastry, S. S. V., Chemical Communications (Cambridge, 2021, 57(73), 9260-9263

Production Method 4

6148-64-7

53663-39-1

944268-58-0

Reaction Conditions

1.1 Reagents: Thionyl chloride ;  2 h, reflux; reflux → rt
1.2 Reagents: Triethylamine ,  Magnesium chloride Solvents: Acetonitrile ;  0 °C; 2.5 h, rt; cooled
1.3 Solvents: Acetonitrile ;  cooled; overnight, rt; 0 °C
1.4 Reagents: Sulfuric acid Solvents: Acetic acid ,  Water ;  3 h, reflux; reflux → rt
1.5 Reagents: Water ;  cooled

Reference

Preparation of phenylacetic acid derivatives as inhibitors of viral replication

, World Intellectual Property Organization, , ,

Production Method 5

53657-94-6

944268-58-0

Reaction Conditions

1.1 Reagents: Sodium nitrite ,  Hydrogen bromide Solvents: Water ;  15 min, 0 °C
1.2 Reagents: Copper bromide (CuBr) ,  Hydrogen bromide ;  60 °C; 30 min, 95 °C; cooled
1.3 Reagents: Water

Reference

Preparation of 2-benzylimidazole derivatives as parasiticides

, United States, , ,

1-(2-Bromo-3-methylphenyl)ethanone Raw materials

• Ethyl potassium malonate
• 1-(2-Amino-3-methylphenyl)ethanone
• Methylmagnesium Chloride (3M in THF)
• 2-Bromo-3-methylbenzoic acid
• 2-Bromo-3-methylbenzaldehyde

1-(2-Bromo-3-methylphenyl)ethanone Preparation Products

• 1-(2-Bromo-3-methylphenyl)ethanone (944268-58-0)

• 1. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
  Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
• 2. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 3. Distinct correlation between (CN2)x units and pores: a low-cost method for predesigned wide range control of micropore size of porous carbon?
  Xiaotong Feng,Lei Bian,Jie Ma,Lei Zhou,Xiayan Wang,Guangsheng Guo,Qiaosheng Pu Chem. Commun., 2019,55, 3963-3966
• 4. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
• 5. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
  Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

• 32937-55-6(2',5'-Dibromoacetophenone)
• 33243-33-3(2',4'-Dibromoacetophenone)
• 13047-06-8((2-Bromophenyl)(phenyl)methanone)
• 2142-69-0(2'-Bromoacetophenone)
• 37074-40-1(1-(4-Bromo-3-methylphenyl)ethanone)
• 67104-64-7(2-Bromo-4'-methylbenzophenone)
• 746651-76-3(2,3'-Dibromobenzophenone)
• 78281-59-1(2,4'-Dibromobenzophenone)
• 137327-29-8(2-Bromo-4'-ethylbenzophenone)
• 294878-58-3(2-Bromo-3'-methylbenzophenone)