- Preparation of 2-benzylimidazole derivatives as parasiticides, United States, , ,
Cas no 944268-56-8 (2-Bromo-6-methylbenzotrifluoride)
2-Bromo-6-methylbenzotrifluoride is a halogenated aromatic compound featuring a bromine substituent at the 2-position and a methyl group at the 6-position of a benzotrifluoride scaffold. This structure imparts unique reactivity, making it a valuable intermediate in organic synthesis, particularly for cross-coupling reactions such as Suzuki or Negishi couplings. The presence of the trifluoromethyl group enhances lipophilicity and metabolic stability, which is advantageous in pharmaceutical and agrochemical applications. Its well-defined reactivity profile and compatibility with various reaction conditions make it a reliable building block for constructing complex molecules. The compound is typically handled under inert conditions to preserve its stability.
944268-56-8 structure
Product Name:2-Bromo-6-methylbenzotrifluoride
CAS No:944268-56-8
MF:C8H6BrF3
MW:239.032452106476
MDL:MFCD01631583
CID:1070872
PubChem ID:45594309
Update Time:2025-06-08
2-Bromo-6-methylbenzotrifluoride Chemical and Physical Properties
Names and Identifiers
-
- 2-Bromo-6-methylbenzotrifluoride
- 1-Bromo-3-methyl-2-(trifluoromethyl)benzene (ACI)
- 1-Bromo-3-methyl-2-(trifluoromethyl)benzene
- 3-bromo-2-(trifluoromethyl)toluene
- SY259213
- AKOS005255488
- DB-079878
- MFCD01631583
- AS-33175
- DTXSID30670710
- 944268-56-8
- EN300-207364
- 1-bromo-3-methyl-2-(trifluoromethyl)benzene;944268-56-8;
- 1-bromo-methyl-2-trifluoromethyl-benzene
- CS-0153709
- SCHEMBL696825
-
- MDL： MFCD01631583
- Inchi： 1S/C8H6BrF3/c1-5-3-2-4-6(9)7(5)8(10,11)12/h2-4H,1H3
- InChI Key： BGTQSQRDRWEFPU-UHFFFAOYSA-N
- SMILES： FC(C1C(C)=CC=CC=1Br)(F)F
Computed Properties
- Exact Mass: 237.96050g/mol
- Monoisotopic Mass: 237.96050g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 0
- Heavy Atom Count: 12
- Rotatable Bond Count: 1
- Complexity: 155
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3.9
- Topological Polar Surface Area: 0?2
Experimental Properties
- Density: 1.538±0.06 g/cm3 (20 oC 760 Torr),
- Boiling Point: 190.0±35.0 oC (760 Torr),
- Flash Point: 76.4±21.8 oC,
- Solubility: Insuluble (2.9E-3 g/L) (25 oC),
2-Bromo-6-methylbenzotrifluoride Security Information
-
Hazardous Material Identification：
- HazardClass：IRRITANT
2-Bromo-6-methylbenzotrifluoride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | B677940-50mg |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 50mg |
$ 50.00 | 2022-06-06 | ||
| TRC | B677940-100mg |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 100mg |
$ 65.00 | 2022-06-06 | ||
| TRC | B677940-500mg |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 500mg |
$ 185.00 | 2022-06-06 | ||
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 032422-1g |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 95% | 1g |
1625CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 032422-25g |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 95% | 25g |
21214CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 032422-5g |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 95% | 5g |
6063CNY | 2021-05-07 | |
| eNovation Chemicals LLC | Y1050403-250mg |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 95+% | 250mg |
$90 | 2024-06-06 | |
| eNovation Chemicals LLC | Y1050403-1g |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 95+% | 1g |
$140 | 2024-06-06 | |
| eNovation Chemicals LLC | Y1050403-5g |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 95+% | 5g |
$320 | 2024-06-06 | |
| Fluorochem | 062793-1g |
2-Bromo-6-methylbenzotrifluoride |
944268-56-8 | 95% | 1g |
￡166.00 | 2022-03-01 |
2-Bromo-6-methylbenzotrifluoride Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Hydrofluoric acid , Sulfur tetrafluoride ; 110 °C
Reference
2-Bromo-6-methylbenzotrifluoride Raw materials
2-Bromo-6-methylbenzotrifluoride Preparation Products
2-Bromo-6-methylbenzotrifluoride Related Literature
-
Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
-
Hui Liu,Deyong Su,Guolin Cheng,Jimin Xu,Xinyan Wang,Yuefei Hu Org. Biomol. Chem., 2010,8, 1899-1904
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3. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imagingGhazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
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Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
944268-56-8 (2-Bromo-6-methylbenzotrifluoride) Related Products
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- 7657-09-2(2,5-Dibromobenzotrifluoride)
- 1192548-06-3(1-Bromo-2,3-bis(trifluoromethyl)benzene)
- 7617-93-8(2-bromo-1,4-bis(trifluoromethyl)benzene)
- 69902-83-6(1-Bromo-2-methyl-3-(trifluoromethyl)benzene)
- 887268-18-0(1-Bromo-2,5-dimethyl-4-(trifluoromethyl)benzene)
- 243128-34-9(1,5-Dibromo-2-methyl-3-(trifluoromethyl)benzene)
- 389130-34-1(Benzene, bromobis(trifluoromethyl)-)
- 64219-37-0(Benzene, 1,2-dibromo-3,4,5-tris(trifluoromethyl)-)
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