- Urea-based polymer with excellent tensile strength and heat resistance for molding material, Japan, , ,
Cas no 943-80-6 (p-Amino-L-phenylalanine)
Technical Introduction: p-Amino-L-phenylalanine
p-Amino-L-phenylalanine is a non-natural amino acid derivative featuring an amino group at the para position of the phenyl ring. This structural modification enhances its utility in peptide synthesis, particularly for introducing aromatic amines as reactive handles in bioconjugation or crosslinking applications. Its chiral L-configuration ensures compatibility with biological systems, making it valuable in pharmaceutical research and the development of modified peptides or protein-based therapeutics. The para-substituted amino group also facilitates selective functionalization, enabling precise chemical modifications. High purity grades are available to meet stringent research and industrial requirements. This compound is commonly used in drug discovery, material science, and biochemical studies.
p-Amino-L-phenylalanine structure
Product Name:p-Amino-L-phenylalanine
CAS No:943-80-6
MF:C9H12N2O2
MW:180.203782081604
MDL:MFCD00069927
CID:40378
PubChem ID:151001
Update Time:2025-05-20
p-Amino-L-phenylalanine Chemical and Physical Properties
Names and Identifiers
-
- 4-Amino-L-phenylalanine
- H-Phe(4-NH2)-OH
- 4-Aminophenylalanine
- 4-Amino-Phe-OH
- H-p-Amino-Phe-OH · HCl
- L-4-aminophe
- L-4-Aminophenylalanine
- p-Amino-L-phenylalanine
- 4-Amino-phenylalanine
- Acetoacetanilide
- Alanine,3-(p-aminophenyl)-, L- (8CI)
- Aminophenylalanine
- L-(+)-p-Aminophenylalanine
- H-p-Amino-Phe-OH HCl
- AC-13622
- p-Amino-L-phenylalanine hydrochloride (Salt/Mix)
- Phenylalanine, 4-amino-
- CHEBI:29737
- AC-5868
- J-300372
- HY-W016480
- Q27110251
- F16190
- AM82697
- CHEMBL231389
- A844939
- 943-80-6
- para-Aminophenylalanine
- MFCD00069927
- AKOS006238125
- (2S)-3-(4-aminophenyl)-2-azanyl-propanoic acid
- PD158334
- L-Phenylalanine, 4-amino-
- (2S)-2-amino-3-(4-aminophenyl)propanoic acid
- AKOS015855687
- para-Amino-phe
- GS-6191
- DTXSID90178828
- Q-101630
- L-4-amino phenylalanine
- UNII-1567B560CH
- L-4-NH2-Phe-OH
- M01306
- 2410-24-4
- p-Aminophenylalanine
- 1567B560CH
- EN300-118972
- SCHEMBL43852
- CS-W017196
- (S)-2-Amino-3-(4-aminophenyl)propionic acid
- 4-Aminophenylalanine #
- (S)-2-amino-3-(4-aminophenyl)propanoic acid
- 4-Amino-L-phenylalanine (ACI)
- L
- Alanine, 3-(p-aminophenyl)-, L- (8CI)
- 4-Amino-L-phenylalanine hydrate
- A2651
-
- MDL： MFCD00069927
- Inchi： 1S/C9H12N2O2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,10-11H2,(H,12,13)/t8-/m0/s1
- InChI Key： CMUHFUGDYMFHEI-QMMMGPOBSA-N
- SMILES： OC([C@H](CC1C=CC(=CC=1)N)N)=O
Computed Properties
- Exact Mass: 180.09000
- Monoisotopic Mass: 180.089877630g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 13
- Rotatable Bond Count: 3
- Complexity: 177
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: nothing
- Topological Polar Surface Area: 89.3?2
Experimental Properties
- Color/Form: White needle like crystals.
- Water Partition Coefficient: Soluble in water.
- PSA: 89.34000
- LogP: 1.50470
- Solubility: Slightly soluble in water.
- Sensitiveness: Air Sensitive
p-Amino-L-phenylalanine Security Information
- WGK Germany：3
- Hazard Category Code： R36/37/38: irritating to eyes, respiratory tract and skin
- Safety Instruction： S26-S36
-
Hazardous Material Identification：
- Risk Phrases：R36/37/38
- HazardClass：IRRITANT
p-Amino-L-phenylalanine Customs Data
- HS CODE：2922499990
- Customs Data：
China Customs Code:
2922499990Overview:
2922499990 Other amino acids and their esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods) MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared
Regulatory conditions:
A.Customs clearance form for Inbound Goods
B.Customs clearance form for outbound goodsInspection and quarantine category:
P.Imported animals and plants\Quarantine of animal and plant products
Q.Outbound animals and plants\Quarantine of animal and plant products
R.Sanitary supervision and inspection of imported food
S.Sanitary supervision and inspection of exported food
M.Import commodity inspection
N.Export commodity inspectionSummary:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
p-Amino-L-phenylalanine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | A105992-1g |
p-Amino-L-phenylalanine |
943-80-6 | 98% | 1g |
￥47.90 | 2023-09-04 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | A105992-25g |
p-Amino-L-phenylalanine |
943-80-6 | 98% | 25g |
￥839.90 | 2023-09-04 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | A105992-250mg |
p-Amino-L-phenylalanine |
943-80-6 | 98% | 250mg |
￥29.90 | 2023-09-04 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | A105992-5g |
p-Amino-L-phenylalanine |
943-80-6 | 98% | 5g |
￥189.90 | 2023-09-04 | |
| Chemenu | CM220294-25g |
(S)-2-Amino-3-(4-aminophenyl)propanoic acid |
943-80-6 | 95% | 25g |
$196 | 2021-06-09 | |
| Chemenu | CM220294-100g |
(S)-2-Amino-3-(4-aminophenyl)propanoic acid |
943-80-6 | 95% | 100g |
$612 | 2021-06-09 | |
| Fluorochem | M01306-1g |
4-Amino-L-phenylalanine |
943-80-6 | 95% | 1g |
￡24.00 | 2022-02-28 | |
| Fluorochem | M01306-5g |
4-Amino-L-phenylalanine |
943-80-6 | 95% | 5g |
￡60.00 | 2022-02-28 | |
| Fluorochem | M01306-10g |
4-Amino-L-phenylalanine |
943-80-6 | 95% | 10g |
￡109.00 | 2022-02-28 | |
| Fluorochem | M01306-25g |
4-Amino-L-phenylalanine |
943-80-6 | 95% | 25g |
￡218.00 | 2022-02-28 |
p-Amino-L-phenylalanine Production Method
Production Method 1
Production Method 2
Reaction Conditions
1.1 Reagents: Hydrochloric acid Solvents: Water ; 18 h, 80 °C
Reference
- Method for inducing environmental stress tolerance in plants, World Intellectual Property Organization, , ,
Production Method 3
Reaction Conditions
1.1 Reagents: Ammonia , Oxygen Solvents: Water ; 36 h, pH 7 - 7.1, 30 °C
Reference
- Ultrastrong, Transparent Polytruxillamides Derived from Microbial PhotodimersTateyama, Seiji; Masuo, Shunsuke; Suvannasara, Phruetchika; Oka, Yuuki; Miyazato, Akio; et al, Macromolecules (Washington, 2016, 49(9), 3336-3342
Production Method 4
Reaction Conditions
1.1 Reagents: Trifluoroacetic acid ; cooled; 30 min, rt
Reference
- Preparation of conjugate containing cyclic peptide and method for producing same, World Intellectual Property Organization, , ,
Production Method 5
Reaction Conditions
Reference
- Synthesis, characterization and inhibitory activities of (4-N3[3,5-3H]Phe10)PKI(6-22)amide and its precursors: photoaffinity labeling peptides for the active site of cyclic AMP-dependent protein kinaseKatz, Bernice M.; Lundquist, Lucy J.; Walsh, Donal A.; Glass, David B., International Journal of Peptide & Protein Research, 1989, 33(6), 439-45
Production Method 6
Reaction Conditions
1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Water ; 3 h, rt
Reference
- Distinct metabolites for photoreactive L-phenylalanine derivatives in Klebsiella sp. CK6 isolated from rhizosphere of a wild dipterocarp saplingWang, Lei; Hisano, Wataru; Murai, Yuta; Sakurai, Munenori; Muto, Yasuyuki; et al, Molecules, 2013, 18, 8393-8401
p-Amino-L-phenylalanine Raw materials
- D(+)-Glucose
- 1,4-Phenylene diisocyanate
- p-Amino-L-phenylalanine
- (2S)-2-amino-3-(4-nitrophenyl)propanoic acid
- (S)-3-(4-Aminophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
p-Amino-L-phenylalanine Preparation Products
p-Amino-L-phenylalanine Suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:943-80-6)4-Amino-L-phenylalanine
Order Number:LE18107
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:17
Price ($):discuss personally
Email:[email protected]
p-Amino-L-phenylalanine Related Literature
-
Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
-
Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
-
Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
-
Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
-
Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
Additional information on p-Amino-L-phenylalanine
Exploring p-Amino-L-phenylalanine: A Comprehensive Overview
p-Amino-L-phenylalanine, identified by the CAS number 943-80-6, is a significant compound in the field of amino acid derivatives. It is a modified version of L-phenylalanine, one of the essential amino acids, with an additional amino group attached to the para position of the benzene ring. This structural modification imparts unique properties to the compound, making it a subject of interest in various scientific and industrial applications.
The synthesis of p-Amino-L-phenylalanine involves advanced chemical techniques, often leveraging stereochemistry to ensure the correct configuration of the amino acid. Recent advancements in asymmetric synthesis have enabled researchers to produce this compound with high enantiomeric excess, which is crucial for its application in chiral environments such as pharmaceuticals and biotechnology. The compound's structure has been extensively studied using techniques like X-ray crystallography and NMR spectroscopy, providing insights into its spatial arrangement and potential interactions with biological systems.
In terms of biological activity, p-Amino-L-phenylalanine has shown promising results in preclinical studies. Researchers have explored its role as a potential precursor for bioactive molecules, including peptides and proteins. Its ability to incorporate into peptide chains without disrupting their secondary structure makes it a valuable tool in peptide synthesis. Moreover, studies have indicated that this compound may exhibit antioxidant properties, which could be beneficial in combating oxidative stress-related diseases.
The application of p-Amino-L-phenylalanine extends beyond basic research into industrial settings. In the food industry, it has been considered as a flavor enhancer due to its ability to modulate taste perception. Additionally, its use in cosmetics has been explored for its potential to improve skin elasticity and reduce signs of aging. These diverse applications highlight the versatility of this compound and its significance in multiple sectors.
Recent breakthroughs in computational chemistry have further enhanced our understanding of p-Amino-L-phenylalanine. Molecular docking studies have revealed potential binding sites on various enzymes, suggesting its role as a lead compound in drug discovery. Furthermore, machine learning algorithms have been employed to predict its pharmacokinetic properties, aiding in the design of more efficient drug delivery systems.
In conclusion, p-Amino-L-phenylalanine (CAS No. 943-80-6) stands out as a versatile and intriguing compound with a wide range of applications. Its unique structure, coupled with advancements in synthetic and computational techniques, positions it as a key player in future research and development across various industries.
943-80-6 (p-Amino-L-phenylalanine) Related Products
- 1012-05-1(2-amino-4-phenyl-butanoic acid)
- 56-45-1(L-Serine)
- 62777-25-7(L-2-Amino-5-phenyl-pentanoic acid)
- 4599-47-7(H-DL-Phe(4-Me)-OH)
- 63-91-2(L-Phenylalanine)
- 57213-48-6(H-Phe(3-CN)-OH)
- 114926-37-3(3-Methyl-L-phenylalanine)
- 63-68-3(L-Methionine)
- 673-06-3(D-Phenylalanine)
- 150-30-1(DL-3-Phenylalanine)
Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:943-80-6)4-Amino-L-phenylalanine
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry