- Piperidine derivatives as aspartic protease inhibitors and their preparation, pharmaceutical compositions and use in the treatment of aspartic protease mediated diseases, World Intellectual Property Organization, , ,
Cas no 942143-25-1 (tert-butyl (3R)-3-acetylpiperidine-1-carboxylate)
942143-25-1 structure
Product Name:tert-butyl (3R)-3-acetylpiperidine-1-carboxylate
CAS No:942143-25-1
MF:C12H21NO3
MW:227.300043821335
MDL:MFCD22682509
CID:4660470
PubChem ID:51922046
Update Time:2024-10-25
tert-butyl (3R)-3-acetylpiperidine-1-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- tert-butyl 3-acetylpiperidine-1-carboxylate
- 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester
- 1-Boc-3-acetyl-piperidine
- 1-Piperidinecarboxylic acid, 3-acetyl-, 1,1-dimethylethyl ester
- 3-acetyl-1-piperidinecarboxylic acid tert-butyl ester
- 1-N-BOC-3-ACETYLPIPERIDINE
- PubChem17598
- (S)-tert-Butyl 3-acetylpiperidine-1-carboxylate
- IIDISJMZFQAYKG-UHFFFAOYSA-N
- WT1069
- RW3787
- RW3106
- 3375AC
- WT819
- 1,1-Dimethylethyl (3R)-3-acetyl-1-piperidinecarboxylate (ACI)
- (R)-1-Boc-3-acetyl-piperidine
- (r)-1-Boc-3-acetylpiperidine
- tert-butyl (3R)-3-acetylpiperidine-1-carboxylate
- MFCD22682509
- tert-butyl(3R)-3-acetylpiperidine-1-carboxylate
- AKOS025403219
- IIDISJMZFQAYKG-SNVBAGLBSA-N
- tert-Butyl (R)-3-acetylpiperidine-1-carboxylate
- SCHEMBL3608462
- CS-0048578
- P13409
- EN300-798870
- (R)-tert-butyl 3-acetylpiperidine-1-carboxylate
- AS-51735
- 942143-25-1
-
- MDL： MFCD22682509
- Inchi： 1S/C12H21NO3/c1-9(14)10-6-5-7-13(8-10)11(15)16-12(2,3)4/h10H,5-8H2,1-4H3/t10-/m1/s1
- InChI Key： IIDISJMZFQAYKG-SNVBAGLBSA-N
- SMILES： C(N1CCC[C@@H](C(=O)C)C1)(=O)OC(C)(C)C
Computed Properties
- Exact Mass: 227.15214353g/mol
- Monoisotopic Mass: 227.15214353g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 16
- Rotatable Bond Count: 3
- Complexity: 281
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 46.6
- XLogP3: 1.3
tert-butyl (3R)-3-acetylpiperidine-1-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM302712-1g |
(R)-1-Boc-3-acetylpiperidine |
942143-25-1 | 95% | 1g |
$621 | 2021-08-18 | |
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FB04400-10g |
tert-butyl (R)-3-acetylpiperidine-1-carboxylate |
942143-25-1 | 95% | 10g |
$1600 | 2023-09-07 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1119186-1g |
tert-Butyl (3S)-3-acetylpiperidine-1-carboxylate |
942143-25-1 | 98+% | 1g |
￥2055.00 | 2024-04-24 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1119186-5g |
tert-Butyl (3S)-3-acetylpiperidine-1-carboxylate |
942143-25-1 | 98+% | 5g |
￥6048.00 | 2024-04-24 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1119186-10g |
tert-Butyl (3S)-3-acetylpiperidine-1-carboxylate |
942143-25-1 | 98+% | 10g |
￥11025.00 | 2024-04-24 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1119186-25g |
tert-Butyl (3S)-3-acetylpiperidine-1-carboxylate |
942143-25-1 | 98+% | 25g |
￥25444.00 | 2024-04-24 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1119186-50g |
tert-Butyl (3S)-3-acetylpiperidine-1-carboxylate |
942143-25-1 | 98+% | 50g |
￥40716.00 | 2024-04-24 | |
| abcr | AB543925-100mg |
(R)-1-Boc-3-Acetylpiperidine; . |
942143-25-1 | 100mg |
€137.00 | 2025-04-15 | ||
| abcr | AB543925-250mg |
(R)-1-Boc-3-Acetylpiperidine; . |
942143-25-1 | 250mg |
€166.20 | 2025-04-15 | ||
| abcr | AB543925-5g |
(R)-1-Boc-3-Acetylpiperidine; . |
942143-25-1 | 5g |
€890.20 | 2025-04-15 |
tert-butyl (3R)-3-acetylpiperidine-1-carboxylate Production Method
Production Method 1
Reaction Conditions
1.1 Solvents: Tetrahydrofuran ; 0.5 h, -15 °C; 4 h, -15 °C → rt
1.2 Reagents: Hydrochloric acid Solvents: Water
1.2 Reagents: Hydrochloric acid Solvents: Water
Reference
tert-butyl (3R)-3-acetylpiperidine-1-carboxylate Raw materials
- Methylmagnesium Chloride (3M in THF)
- 1-Piperidinecarboxylic acid, 3-[(MethoxyMethylaMino)carbonyl]-, 1,1-diMethylethyl ester, (3R)-
tert-butyl (3R)-3-acetylpiperidine-1-carboxylate Preparation Products
tert-butyl (3R)-3-acetylpiperidine-1-carboxylate Related Literature
-
Pavel Karásek,Jakub Grym,Michal Roth,Josef Planeta,Franti?ek Foret Lab Chip, 2015,15, 311-318
-
Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
-
Gerald J. Meyer,Leif Hammarstr?m Chem. Sci., 2020,11, 3460-3473
-
Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
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