- Preparation of harmful animal control compositions comprising condensed imidazole compounds and kasugamycin, and method for controlling harmful animal, Japan, , ,
Cas no 937602-15-8 (N-Methyl-5-(trifluoromethyl)pyridin-2-amine)
N-Methyl-5-(trifluoromethyl)pyridin-2-amine is a fluorinated pyridine derivative with a trifluoromethyl group at the 5-position and a methylamino substituent at the 2-position. This compound is valued for its electron-withdrawing trifluoromethyl group, which enhances its reactivity and stability in various chemical transformations. The methylamino moiety further contributes to its utility as an intermediate in pharmaceutical and agrochemical synthesis. Its structural features make it suitable for applications in medicinal chemistry, particularly in the development of bioactive molecules. The compound is typically handled under controlled conditions due to its sensitivity, ensuring high purity and consistency for research and industrial use.
937602-15-8 structure
Product Name:N-Methyl-5-(trifluoromethyl)pyridin-2-amine
CAS No:937602-15-8
MF:C7H7F3N2
MW:176.139091730118
MDL:MFCD08689790
CID:827554
PubChem ID:18526206
Update Time:2025-10-29
N-Methyl-5-(trifluoromethyl)pyridin-2-amine Chemical and Physical Properties
Names and Identifiers
-
- N-Methyl-5-(trifluoromethyl)pyridin-2-amine
- 2-(METHYLAMINO)-5-(TRIFLUOROMETHYL)PYRIDINE
- N-Methyl-5-(trifluoromethyl)-2-pyridinamine
- methyltrifluoromethylpyridinamine
- ALRNMRIFTCZDDH-UHFFFAOYSA-N
- SBB089141
- 3707AF
- 2-methylamino-5-trifluoromethylpyridine
- AK142761
- 2-Pyridinemethanamine,5-(trifluoromethyl)-
- BB 0255210
- methyl[5-(trifluoromethyl)(2-pyridyl)]amine
- N-methyl(5-trifluoro
- N-Methyl-5-(trifluoromethyl)-2-pyridinamine (ACI)
- N-Methyl(5-trifluoromethylpyridin-2-yl)amine
- methyl-(5-trifluoromethyl-pyridin-2-yl)-amine
- DTXSID50594803
- C77231
- KRDPJMKGSDSKLC-UHFFFAOYSA-N
- N-methyl-(5-trifluoromethyl-pyridin-2-yl)-amine
- N-methyl-(5-trifluoromethylpyridin-2-yl)-amine
- 937602-15-8
- N-methyl(5-trifluoromethylpyridin-2-yl)-amine
- J-523665
- 2-Methylamino-5-(trifluoromethyl)pyridine
- A1-02432
- CS-0099414
- SCHEMBL116298
- EN300-1264138
- AKOS005072862
- MFCD08689790
- N-methyl-(5-trifluoromethylpyridine-2-yl)-amine
- SB52389
- HA-0702
-
- MDL: MFCD08689790
- Inchi: 1S/C7H7F3N2/c1-11-6-3-2-5(4-12-6)7(8,9)10/h2-4H,1H3,(H,11,12)
- InChI Key: ALRNMRIFTCZDDH-UHFFFAOYSA-N
- SMILES: FC(C1C=CC(NC)=NC=1)(F)F
Computed Properties
- Exact Mass: 176.05600
- Monoisotopic Mass: 176.05613272g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 12
- Rotatable Bond Count: 1
- Complexity: 146
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.1
- Topological Polar Surface Area: 24.9
Experimental Properties
- Melting Point: 91-93
- PSA: 24.92000
- LogP: 2.21510
N-Methyl-5-(trifluoromethyl)pyridin-2-amine Security Information
- Hazard Statement: Irritant
-
Hazardous Material Identification:
- HazardClass:IRRITANT
N-Methyl-5-(trifluoromethyl)pyridin-2-amine Customs Data
- HS CODE:2933399090
- Customs Data:
China Customs Code:
2933399090Overview:
2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
N-Methyl-5-(trifluoromethyl)pyridin-2-amine Pricemore >>
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| Fluorochem | 043354-250mg |
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| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | N188420-5g |
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N-Methyl-5-(trifluoromethyl)pyridin-2-amine Production Method
Production Method 1
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
Production Method 2
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- harmful animal control compositions containing condensed imidazole compounds and diclocymet, tricyclazole, fthalide, or pyroquilon, Japan, , ,
Production Method 3
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Harmful animal control compositions containing condensed imidazole compounds and validamycin and method for controlling harmful animal, Japan, , ,
Production Method 4
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Harmful animal control compositions containing condensed imidazole compounds and respiratory inhibitors and method for controlling harmful animal, Japan, , ,
Production Method 5
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Preparation of harmful animal control compositions comprising condensed imidazole derivative and 4-oxo-4-[(2-phenylethyl)amino]butyric acid, Japan, , ,
Production Method 6
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Preparation of fused benzimidazole derivatives and pest control composition containing them and method for controlling pests, Japan, , ,
Production Method 7
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Harmful animal control compositions containing condensed imidazole compounds and cartap hydrochloride and method for controlling harmful animals, World Intellectual Property Organization, , ,
Production Method 8
Reaction Conditions
1.1 Solvents: Acetonitrile , Water ; 6 h, 25 °C; 8 h, 25 °C
Reference
- Method for producing triazole compound, World Intellectual Property Organization, , ,
Production Method 9
Reaction Conditions
1.1 Solvents: Acetonitrile ; overnight, 100 °C
Reference
- Preparation of sulfur-containing polycyclic compound as agricultural insecticide, China, , ,
Production Method 10
Reaction Conditions
1.1 4 h, reflux; reflux → rt
1.2 Reagents: Water ; cooled
1.2 Reagents: Water ; cooled
Reference
- A simple synthesis of aminopyridines: use of amides as amine sourceKodimuthali, Arumugam; Mungara, Anitha; Prasunamba, Padala Lakshmi; Pal, Manojit, Journal of the Brazilian Chemical Society, 2010, 21(8), 1439-1445
Production Method 11
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 6 h, rt
Reference
- Preparation of condensed heterocyclic compounds as agricultural and horticultural pesticides, Japan, , ,
Production Method 12
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Preparation of fused heterocyclic compounds and use for pest control thereof, World Intellectual Property Organization, , ,
Production Method 13
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Harmful animal control compositions containing condensed imidazole compounds and pencycuron and method for controlling harmful animal, Japan, , ,
Production Method 14
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Harmful animal control compositions containing condensed imidazole compounds and resistance-inducing compounds and method for controlling harmful animal, Japan, , ,
Production Method 15
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Preparation of pest control compositions comprising condensed imidazole derivative and pyridalyl, Japan, , ,
Production Method 16
Reaction Conditions
1.1 Solvents: N-Methyl-2-pyrrolidone , Water ; 3 h, rt
Reference
- Preparation of pest control compositions comprising condensed imidazole derivative and pyrethroid-compound, Japan, , ,
N-Methyl-5-(trifluoromethyl)pyridin-2-amine Raw materials
N-Methyl-5-(trifluoromethyl)pyridin-2-amine Preparation Products
N-Methyl-5-(trifluoromethyl)pyridin-2-amine Related Literature
-
Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
-
Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640
-
Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
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Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
937602-15-8 (N-Methyl-5-(trifluoromethyl)pyridin-2-amine) Related Products
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