Production Method 1

73183-34-3

179898-34-1

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium acetate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ;  18 h, 100 °C

Reference

1,3-Thiazol-2-ylbenzamides as P2X purinoceptor antagonists and their preparation

, World Intellectual Property Organization, , ,

Production Method 2

73183-34-3

179898-34-1

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium acetate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ;  2 h, 90 °C

Reference

Preparation of indolizine derivatives as phoshoinositide 3-kinases inhibitors

, United States, , ,

Production Method 3

73183-34-3

179898-34-1

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium acetate Catalysts: Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane addu… Solvents: Dimethyl sulfoxide ,  1,4-Dioxane ;  overnight, 90 °C

Reference

Substituted (thiazolylcarbonyl)imidazolidinones as antiretroviral agents and their preparation and use in the treatment of retroviral diseases

, World Intellectual Property Organization, , ,

Production Method 4

327056-73-5

73183-34-3

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium acetate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ;  2 h, rt → 110 °C

Reference

Preparation of triazine-containing organic compounds for organic electroluminescent device

, China, , ,

Production Method 5

179898-34-1

935685-88-4

Reaction Conditions

Reference

Preparation of 8-substituted isoquinoline derivatives as IKKβ kinase inhibitors

, World Intellectual Property Organization, , ,

Production Method 6

73183-34-3

179898-34-1

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium acetate Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: Dichloromethane ,  1,4-Dioxane ;  4 h, 80 °C

Reference

Thiazolyl derivatives as mGluR5 antagonists and their preparation and methods for their use

, World Intellectual Property Organization, , ,

Production Method 7

935685-88-4

Reaction Conditions

Reference

Substituted (thiazolylcarbonyl)imidazolidinones as antiretroviral agents and their preparation and use in the treatment of retroviral diseases

, Germany, , ,

Production Method 8

73183-34-3

179898-34-1

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium acetate Catalysts: Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane addu… Solvents: Dimethyl sulfoxide ,  1,4-Dioxane ;  overnight, 90 °C

Reference

Substituted (thiophenylcarbonyl)imidazolidinones and their preparation and use for the treatment and/or prevention of retroviral diseases

, World Intellectual Property Organization, , ,

Production Method 9

73183-34-3

179898-34-1

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium carbonate Catalysts: Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane addu… Solvents: Dimethyl sulfoxide ,  1,4-Dioxane ;  overnight, 90 °C

Reference

Preparation of N-heterocyclyl furancarboxamides as anti-AIDS drugs.

, World Intellectual Property Organization, , ,

Production Method 10

73183-34-3

179898-34-1

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium acetate Catalysts: Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane addu… Solvents: Dimethylformamide ;  24 h, 100 °C

Reference

Condensed cyclic compound, composition including the same, and organic light-emitting device including the condensed cyclic compound

, United States, , ,

Production Method 11

73183-34-3

179898-34-1

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium acetate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: Dimethylformamide ;  6 h, 110 °C

Reference

Preparation biaryl oxyacetic acid compounds as inhibitors of CRTH2 receptor

, World Intellectual Property Organization, , ,

Production Method 12

73183-34-3

935685-88-4

Reaction Conditions

1.1 Reagents: Potassium acetate Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: 1,4-Dioxane ;  4 h, 100 °C

Reference

Preparation of 1,2,3,4-tetrahydroquinoxaline derivatives useful as RORγt agonists useful for the treatment of cancers, metabolic diseases and autoimmune diseases

, World Intellectual Property Organization, , ,

Production Method 13

935685-88-4

Reaction Conditions

Reference

Preparation of N-heterocyclyl furancarboxamides as anti-AIDS drugs.

, Germany, , ,

Production Method 14

935685-88-4

Reaction Conditions

Reference

Substituted (thiophenylcarbonyl)imidazolidinones and their preparation and use for the treatment and/or prevention of retroviral diseases

, Germany, , ,

3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2dioxaborolan-2-yl)-benzonitrile Raw materials

• 3-Chloro-5-fluorobenzonitrile
• Bis(pinacolato)diborane
• 3-Bromo-5-fluorobenzonitrile

3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2dioxaborolan-2-yl)-benzonitrile Preparation Products

• 3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2dioxaborolan-2-yl)-benzonitrile (935685-88-4)

• 1. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 2. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imaging
  Ghazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
• 3. Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers?
  Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
• 4. Emerging investigator series: kinetics of diopside reactivity for carbon mineralization in mafic–ultramafic rocks
  BrianaAguila,LandonHardee,H.ToddSchaef,SiavashZare,MohammadJavadAbdolhosseiniQomi,JarrodV.Crum,JadeE.HollimanJr.,ElenaTajueloRodriguez,LawrenceM.Anovitz,KevinM.Rosso,QuinR.S.Miller
• 5. Excited state potential energy surfaces and their interactions in FeIVO active sites
  Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577

• 815631-56-2(4-Fluoro-2-methylphenylboronic acid, pinacol ester)
• 461451-63-8(5-fluoro-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile)
• 1035235-29-0(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile)
• 863868-29-5(4-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile)
• 903895-56-7(3-Fluoro-4-methylphenylboronic acid, pinacol ester)
• 1003298-73-4(2,6-difluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile)
• 1192023-08-7(4-Cyano-2-fluoro-5-methylphenylboronic acid, pinacol ester)
• 765916-91-4(2-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile)
• 775351-57-0(3-Cyano-4-fluorophenylboronic acid, pinacol ester)
• 463335-96-8(2-Cyano-5-fluorophenylboronic acid pinacol ester)