Cas no 93479-97-1 (Glimepiride)

Glimepiride is a third-generation sulfonylurea oral antidiabetic agent used in the management of type 2 diabetes mellitus. It functions by stimulating insulin secretion from pancreatic beta cells through the inhibition of ATP-sensitive potassium channels. Glimepiride exhibits high selectivity for pancreatic sulfonylurea receptors, contributing to its efficacy in glycemic control with a lower risk of extrapancreatic effects. Its extended half-life allows for once-daily dosing, enhancing patient compliance. Additionally, Glimepiride demonstrates a favorable safety profile with a reduced incidence of hypoglycemia compared to earlier sulfonylureas. It is often used as monotherapy or in combination with other antidiabetic agents to achieve optimal blood glucose regulation.
Glimepiride structure
Glimepiride structure
Product Name:Glimepiride
CAS No:93479-97-1
MF:C24H34N4O5S
MW:490.615564823151
MDL:MFCD00878417
CID:61633
PubChem ID:160870906
Update Time:2025-08-05

Glimepiride Chemical and Physical Properties

Names and Identifiers

    • Glimepiride
    • glimepirid
    • hoe490
    • 1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea
    • amary
    • AMARYL
    • Glimperide
    • CLIMEPIRIDE
    • GliMepiride COS
    • Glimpiride
    • Grimepride
    • trans-3-Ethyl-2,5-dihydro-4-methyl-N-[N-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide
    • HOE-490
    • Glimepiride impurity
    • Amarel
    • Glimepiridum
    • Glimepirida
    • Endial
    • Glimepride
    • cis-Glimepiride
    • Glimepiridum [Latin]
    • HOE 490
    • Glimepirida [Spanish]
    • Glista OD
    • 4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide
    • 1-((p-(2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl)phenyl)sulfonyl)-3-(trans-4-methylcyclohexyl)urea
    • 24T6XIR2MZ
    • 1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-, trans- (ZCI)
    • 3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide (ACI)
    • Diameprid
    • Dibiglim
    • Glimax
    • Glirid
    • GlucoNovax
    • Limeral
    • trans-3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl] 2-oxo-1H-pyrrole-1-carboxamide
    • ZINC 537791
    • BRD-K34776109-001-03-4
    • BRD-K42693031-001-01-8
    • STL451059
    • MLS006011260
    • gimepiride
    • Prestwick1_000651
    • CHEMBL1481
    • GLIMEPIRIDE [MART.]
    • BDBM50237590
    • Glimepiride, United States Pharmacopeia (USP) Reference Standard
    • DUETACT COMPONENT GLIMEPIRIDE
    • boxamide
    • CCG-101156
    • Glimepiride 100 microg/mL in Acetonitrile
    • 684286-46-2
    • NSC813217
    • HY-B0104
    • UNII-6KY687524K
    • GLIMEPIRIDE [MI]
    • HMS1570C03
    • 3-ethyl-4-methyl-N-(4-(N-(((1r,4r)-4-methylcyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
    • Pharmakon1600-01504915
    • Glimepiride, European Pharmacopoeia (EP) Reference Standard
    • Sugral
    • AC-476
    • 1-{[4-(2-{[(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)carbonyl]amino}ethyl)phenyl]sulfonyl}-3-(trans-4-methylcyclohexyl)urea
    • CHEMBL149223
    • AB00513874-08
    • 1H-PYRROLE-1-CARBOXAMIDE, 3-ETHYL-2,5-DIHYDRO-4-METHYL-N-(2-(4-(((((CIS-4-METHYLCYCLOHEXYL)AMINO)CARBONYL)AMINO)SULFONYL)PHENYL)ETHYL)-2-OXO-
    • 3-ETHYL-4-METHYL-N-(4-(N-((1R,4R)-4-METHYLCYCLOHEXYLCARBAMOYL)SULFAMOYL)PHENETHYL)-2-OXO-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE
    • 1H-Pyrrole-1-carboxamide, 2,5-dihydro-3-ethyl-4-methyl-N-(2-(4-(((((4-methylcyclohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo-, trans-
    • Prestwick0_000651
    • HMS3677K06
    • SCHEMBL8738802
    • Glimepiride Impurity A
    • CS-1844
    • SR-05000001508-3
    • NSC 759809
    • s1344
    • DTXCID3020675
    • Glemax
    • GLIMEPIRIDE [WHO-DD]
    • GLIMEPIRIDE [USP-RS]
    • MFCD00878417
    • BSPBio_000681
    • 3-Ethyl-4-Methyl-N-[2-(4-{[(Cis-4-Methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-Oxo-2,5-Dihydro-1h-Pyrrole-1-Carboxamide
    • NC00406
    • NCGC00016960-01
    • AB00513874-09
    • BRD-K34776109-001-15-8
    • Ristomycin Monosulfate (90%)
    • GLIMEPIRIDE [USAN]
    • SPBio_002602
    • 1-((4-(2-(((3-ETHYL-4-METHYL-2-OXO-2,3-DIHYDRO-1H-PYRROL-1-YL)CARBONYL)AMINO)ETHYL)PHENYL)SULFONYL)-3-(CIS-4-METHYLCYCLOHEXYL)UREA
    • DTXSID5040675
    • BRD-K34776109-001-14-1
    • Tox21_110713
    • SCHEMBL14371714
    • BG164507
    • SCHEMBL26496475
    • Amaryl (TN)
    • N'-{[4-(2-{[(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)carbonyl]amino}ethyl)phenyl]sulfonyl}-N-(4-methylcyclohexyl)carbamimidic acid
    • SMR000466368
    • 93479-97-1
    • BCP05331
    • HMS2235L07
    • Glimepiride, >=98% (HPLC), solid
    • 3-ethyl-4-methyl-N-{2-[4-({[(4-methylcyclohexyl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
    • HMS3654F17
    • N-[4-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)-ethyl]-benzenesulfonyl]-N'-4-methylcyclohexylurea
    • trans-1-(4-(2-(3-ethyl-4-Me-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamido)ethyl)phenylsulfonyl)-3-(4-methylcyclohexyl)urea
    • BRD-K34776109-001-16-6
    • Glimepiride [USAN:USP:INN:BAN]
    • MLS000759495
    • NCGC00016960-05
    • 3-ethyl-4-methyl-N-[2-(4-{[(4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
    • EN300-19873446
    • AB00513874_11
    • Solosa
    • GLIMEPIRIDE [EP MONOGRAPH]
    • NS00004860
    • CCRIS 7083
    • 3-ethyl-4-methyl-N-[2-(4-{[(trans-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
    • C07669
    • SR-05000001508-2
    • 3-ethyl-4-methyl-N-(4-(N-(((1s,4s)-4-methylcyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide? (Glimepiride Impurity pound(c)
    • Prestwick2_000651
    • Oprea1_382896
    • STL453194
    • Q425027
    • NCGC00016960-07
    • NCGC00161404-02
    • 1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-(2-(4-(((((4-methylcyclohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo-, trans-
    • 3-Ethyl-4-methyl-N-(4-(N-((rel-(1r,4r)-4-methylcyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
    • 3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide
    • Ristocetin Sulfate; Ristomycin Sulfate
    • 1-[[4-[2-[[(3-Ethyl-4-methyl-2-oxo-2,3-dihydro-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulphonyl]-3-(cis-4-methylcyclohexyl)urea (cis-Glimepiride)
    • CHEBI:92609
    • HMS3372O07
    • Glimepiride, British Pharmacopoeia (BP) Reference Standard
    • trans-3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methyl cyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide
    • Roname
    • HMS3269A09
    • Glimepiride; 3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl] 2-oxo-1H-pyrrole-1-carboxamide; Amaryl; Glimperide; HOE 490; trans-3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl] 2-oxo-1H-pyrrole-1-carboxamide
    • NCGC00371061-02
    • CPD000466368
    • Tox21_110713_1
    • Glymepirid
    • NCGC00371061-06
    • SCHEMBL16086
    • D00593
    • 1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans- 4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-
    • 3-ethyl-4-methyl-N-[2-(4-{[(cis-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-car
    • GTPL6820
    • GLIMEPIRIDE [ORANGE BOOK]
    • SR-05000001508-1
    • AB00513874
    • Q27253874
    • HMS2097C03
    • Glimepiride for system suitability, European Pharmacopoeia (EP) Reference Standard
    • NSC759809
    • AB00513874_10
    • 6KY687524K
    • SCHEMBL14965363
    • SR-05000001508
    • MLS001076674
    • 3-ethyl-4-methyl-N-(4-(N-((1r,4r)-4-methylcyclohexylcarbamoyl)
    • HMS3714C03
    • BCP9000728
    • NCGC00016960-04
    • BPBio1_000751
    • Trans-3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide
    • Z1501475009
    • GLIMEPIRIDE [VANDF]
    • Glimepiride for system suitability
    • 3-ethyl-4-methyl-N-[2-(4-{[(cis-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-car boxamide
    • UNII-24T6XIR2MZ
    • Glimepiride,(S)
    • GLIMEPIRIDE IMPURITY A [EP IMPURITY]
    • CHEBI:5383
    • SL-NH2 Trifluoroacetic Acid Salt (1:2)
    • GLIMEPIRIDE [INN]
    • GLIMEPIRIDE [USP IMPURITY]
    • MLS001401419
    • 261361-60-8
    • AB00513874-06
    • 3-ethyl-4-methyl-2-oxo-N-(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide
    • G0395
    • Glimepiride- Bio-X
    • HMS2052L03
    • AKOS015894919
    • AKOS015969663
    • Amaryl, Glista OD
    • Q-201158
    • NSC-759809
    • NCGC00181757-01
    • Niddaryl
    • Prestwick3_000651
    • SCHEMBL16084
    • 3-ethyl-4-methyl-n-(4-(n-((1r,4r)-4-methylcyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro
    • MLS003915622
    • NCGC00161404-01
    • GLIMEPIRIDE [EMA EPAR]
    • Glimepiride, cis-
    • HMS3394L03
    • GLIMEPIRIDE [USP MONOGRAPH]
    • sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
    • Glimer
    • SW196369-4
    • AB07644
    • Glorion
    • GLIMEPIRIDE CIS-ISOMER
    • GLIMEPIRIDE [JAN]
    • Glimepiride (JP18/USP/INN)
    • NCGC00016960-02
    • BRN 5365754
    • HMS2090K18
    • CAS-93479-97-1
    • HMS3413K06
    • KS-5238
    • SMR001550123
    • NCGC00016960-03
    • DB00222
    • DTXSID20861130
    • CS-0165191
    • NSC-813217
    • MDL： MFCD00878417
    • Inchi： 1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
    • InChI Key： WIGIZIANZCJQQY-RUCARUNLSA-N
    • SMILES： C(N1CC(C)=C(CC)C1=O)(=O)NCCC1C=CC(S(=O)(=O)NC(=O)N[C@@H]2CC[C@@H](C)CC2)=CC=1
    • BRN： 5365754

Computed Properties

  • Exact Mass: 490.22500
  • Monoisotopic Mass: 490.224991
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 34
  • Rotatable Bond Count: 7
  • Complexity: 895
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 133
  • Surface Charge: 0
  • Tautomer Count: 6
  • XLogP3: 3.9

Experimental Properties

  • Color/Form: Powder
  • Density: 1.29
  • Melting Point: 202.0 to 206.0 deg-C
  • Boiling Point: No data available
  • Flash Point: No data available
  • Refractive Index: 1.599
  • Solubility: DMSO: >10?mg/mL
  • PSA: 133.06000
  • LogP: 5.26540
  • Merck: 4440
  • Solubility: Not determined

Glimepiride Security Information

Glimepiride Customs Data

  • HS CODE：2935009090
  • Customs Data：

    China Customs Code:

    2935009090

    Overview:

    2935009090 Other sulphonates(Acyl)amine. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:35.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Glimepiride Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
MedChemExpress
HY-B0104-10mM*1mLinDMSO
Glimepiride
 93479-97-1 98.44%
10mM*1mLinDMSO
 ￥550 2023-07-26
MedChemExpress
HY-B0104-500mg
Glimepiride
 93479-97-1 99.92%
500mg
 ￥500 2025-04-15
MedChemExpress
HY-B0104-1g
Glimepiride
 93479-97-1 99.92%
1g
 ￥837 2025-04-15
MedChemExpress
HY-B0104-5g
Glimepiride
 93479-97-1 99.92%
5g
 ￥2850 2025-04-15
YUN NAN XI LI SHENG WU JI SHU GU FEN Co., Ltd.
BBP80103-5mg
Glimepiride
 93479-97-1 98.0%
5mg
 ￥100 2021-05-07
AstaTech
45380-1/G
GLIMEPIRIDE
 93479-97-1 97%
1g
 $167 2023-09-17
AstaTech
45380-5/G
GLIMEPIRIDE
 93479-97-1 97%
5g
 $500 2023-09-17
TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd.
G0395-5G
Glimepiride
 93479-97-1 >98.0%(T)(HPLC)
5g
 ￥560.00 2024-04-15
Fluorochem
036559-1g
Glimepiride
 93479-97-1 97%
1g
 ￡67.00 2022-03-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
G129354-5g
Glimepiride
 93479-97-1 ≥99%
5g
 ￥1792.90 2023-09-02

Glimepiride Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  7 h, rt
Reference
Preparation method of glimepiride for anti-diabetes drug
, China, , ,

Production Method 2

Reaction Conditions
1.1 Reagents: Potassium carbonate Solvents: Tetrahydrofuran ;  1 - 2 h, rt → 65 °C
1.2 Solvents: Toluene ;  10 - 12 h, 60 - 65 °C; cooled
1.3 Reagents: Ammonia Solvents: Methanol ;  pH 10 - 12
1.4 Reagents: Acetic acid ;  pH 5.5 - 6.0, 25 - 30 °C
Reference
A process for purification of glimepiride
, India, , ,

Production Method 3

Reaction Conditions
1.1 Reagents: Sodium methoxide Solvents: Dimethyl sulfoxide
1.2 Reagents: Water
Reference
Improved process for the preparation of benzenesulfonylureas used as second-generation oral hypoglycemic agents
, World Intellectual Property Organization, , ,

Production Method 4

Reaction Conditions
1.1 Solvents: Toluene
Reference
Studies on synthetic process of glimepiride, new hypoglycemic agent
Deng, Yong; Zhong, Yuguo; Tang, Weigao; Zhong, Zhicheng, Zhongguo Yaowu Huaxue Zazhi, 2000, 10(2), 134-137

Production Method 5

Reaction Conditions
1.1 Solvents: Toluene ;  rt
1.2 rt → reflux; 4 h, reflux; reflux → 15 °C
Reference
Process for preparing glimepiride and corresponding intermediate
, Czech Republic, , ,

Production Method 6

Reaction Conditions
1.1 Reagents: Triethylamine ,  Ethyl chloroformate Solvents: Dichloromethane ;  2 h, 20 - 25 °C
1.2 Reagents: Acetic acid Solvents: Water ;  pH 4 - 4.2; 30 min
1.3 Reagents: 4-(Dimethylamino)pyridine Solvents: Toluene ;  rt → reflux; 3 h, reflux; reflux → 30 °C; 3 h, 25 - 30 °C
Reference
An improved process for the preparation of N-{2-[4-(aminosulfonyl)phenyl]ethyl}-3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide, a key intermediate in the synthesis of glimepiride
, India, , ,

Production Method 7

Reaction Conditions
1.1 Reagents: Diisopropylethylamine Solvents: Dimethylformamide ;  3 h, rt → 25 °C
1.2 Solvents: Dimethylformamide ;  overnight, heated
Reference
Preparation method of glimepiride
, China, , ,

Production Method 8

Reaction Conditions
1.1 Reagents: Potassium carbonate Solvents: Acetonitrile ;  rt → 60 °C
1.2 6 h, 50 - 60 °C
1.3 Reagents: Hydrochloric acid Solvents: Water ;  pH 1 - 2, 20 - 25 °C
Reference
Synthetic preparation of glimepiride bulk drug
, China, , ,

Production Method 9

Reaction Conditions
1.1 Solvents: tert-Butyl methyl ether
1.2 Solvents: Toluene ,  Cyclohexanone ,  tert-Butyl methyl ether ;  10 h, 30 °C
Reference
Method for preparing hypoglycemic drug glimepiride
, China, , ,

Production Method 10

Reaction Conditions
1.1 Reagents: 4-(Dimethylamino)pyridine Solvents: Toluene ;  rt → reflux
Reference
Method for the manufacture of compounds related to the class of substituted sulfonyl urea antidiabetics
, European Patent Organization, , ,

Production Method 11

Reaction Conditions
1.1 Reagents: Potassium carbonate Solvents: Acetone ,  Methyl ethyl ketone ;  30 min, rt → reflux
1.2 5 - 6 h, reflux
1.3 Reagents: Hydrochloric acid Solvents: Water ;  pH 6
Reference
Preparation of glimepiride
, China, , ,

Production Method 12

Reaction Conditions
1.1 Reagents: Potassium carbonate Solvents: Acetone ;  1 h, 55 - 60 °C
1.2 Solvents: Toluene ;  12 h, reflux
1.3 Reagents: Acetic acid Solvents: Water ;  pH 5.5 - 6, 20 - 25 °C
Reference
A novel process for preparation of substantially pure glimepiride
, World Intellectual Property Organization, , ,

Production Method 13

Reaction Conditions
1.1 Reagents: 1,8-Diazabicyclo[5.4.0]undec-7-ene Solvents: Acetonitrile ;  5 h, reflux
Reference
An Efficient and Practical Process for the Synthesis of Glimepiride
Tanwar, Dinesh Kumar; Surendrabhai, Vaghela Ravikumar; Gill, Manjinder Singh, Synlett, 2017, 28(18), 2495-2498

Production Method 14

Reaction Conditions
1.1 Reagents: Potassium carbonate Solvents: Acetone ;  6 h, reflux
1.2 6 h, reflux; reflux → rt
1.3 Reagents: Hydrochloric acid Solvents: Water ;  pH 2
Reference
studies on the preparation of glimepiride
Liu, Sheng-gao, Shandong Huagong, 2009, 38(6), 14-15

Production Method 15

Reaction Conditions
1.1 Reagents: Potassium carbonate Solvents: Acetone ;  6 h, reflux
1.2 8 h, reflux; reflux → rt
1.3 Reagents: Hydrochloric acid Solvents: Water ;  pH 1 - 2
Reference
Synthesis of 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide (glimepiride)
Liu, Zhanke; Yang, Xinwu; Lu, Qihui; Wang, Xiaoguang; Liu, Zhiling, Jingxi Huagong Zhongjianti, 2006, 36(3), 16-18

Production Method 16

Reaction Conditions
1.1 Reagents: Sodium hydroxide ,  Zinc chloride Solvents: Dimethylformamide ,  Water ;  pH 6.5 - 8, rt; 3 h, 80 °C
Reference
Synthesis, physico-chemical and antidiabetic studies of zinc complex of glimepiride, an oral hypoglycemic agent
Jacob, George, Oriental Journal of Chemistry, 2013, 29(4), 1351-1358

Glimepiride Raw materials

Glimepiride Preparation Products

Glimepiride Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:93479-97-1)Glimepiride
Order Number:A844609
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 07:03
Price ($):337.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:93479-97-1)格列吡咯
Order Number:LE25877165;LE12400
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:50
Price ($):discuss personally
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:93479-97-1)Glimepiride
Order Number:sfd18752
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally
Zhengzhou Baoyu Pharmaceutical Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
(CAS:93479-97-1)Glimepiride
Order Number:LE341
Stock Status:in Stock
Quantity:5KG/1KG/25KG/100KG
Purity:99% HPLC
Pricing Information Last Updated:Thursday, 14 August 2025 14:44
Price ($):negotiated

Glimepiride Spectrogram

13C NMR
13C NMR
MS-MS
MS-MS
1H NMR 300 MHz DMSO
1H NMR

Glimepiride Related Literature

93479-97-1 (Glimepiride) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:93479-97-1)Glimepiride
A844609
Purity:99%
Quantity:25g
Price ($):337.0
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:93479-97-1)格列吡咯
LE25877165;LE12400
Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
Email