- Preparation of 6-aza-quinoline derivatives for preventing or treating cancer in patients with oncogenic mutations in the BRAF gene and B-Raf protein, World Intellectual Property Organization, , ,
Cas no 934016-09-8 (Methyl 4-acetylpicolinate)
Methyl 4-acetylpicolinate structure
Product Name:Methyl 4-acetylpicolinate
CAS No:934016-09-8
MF:C9H9NO3
MW:179.172662496567
MDL:MFCD18256188
CID:1091270
PubChem ID:69248921
Update Time:2025-08-03
Methyl 4-acetylpicolinate Chemical and Physical Properties
Names and Identifiers
-
- 4-acetyl-2-Pyridinecarboxylic acid methyl ester
- Methyl 4-acetylpicolinate
- methyl 4-acetylpyridine-2-carboxylate
- GZLDGDOOYSWNMY-UHFFFAOYSA-N
- FCH1150140
- AK145099
- AX8283189
- DB-209331
- DS-7989
- SB53093
- AKOS022176884
- Methyl4-acetylpicolinate
- MFCD18256188
- SCHEMBL4939178
- CS-0095190
- C77204
- SY316997
- 934016-09-8
-
- MDL： MFCD18256188
- Inchi： 1S/C9H9NO3/c1-6(11)7-3-4-10-8(5-7)9(12)13-2/h3-5H,1-2H3
- InChI Key： GZLDGDOOYSWNMY-UHFFFAOYSA-N
- SMILES： O=C(C1C=C(C(C)=O)C=CN=1)OC
Computed Properties
- Exact Mass: 179.058243149g/mol
- Monoisotopic Mass: 179.058243149g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 13
- Rotatable Bond Count: 3
- Complexity: 215
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 56.3
- XLogP3: 0.7
Methyl 4-acetylpicolinate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029207931-250mg |
Methyl 4-acetylpicolinate |
934016-09-8 | 95% | 250mg |
$156.56 | 2023-08-31 | |
| Alichem | A029207931-1g |
Methyl 4-acetylpicolinate |
934016-09-8 | 95% | 1g |
$387.60 | 2023-08-31 | |
| Alichem | A029207931-5g |
Methyl 4-acetylpicolinate |
934016-09-8 | 95% | 5g |
$1128.60 | 2023-08-31 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | M875897-500mg |
Methyl 4-acetylpyridine-2-carboxylate |
934016-09-8 | ≥97% | 500mg |
1,708.20 | 2021-05-17 | |
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FD02630-25g |
Methyl 4-acetylpicolinate |
934016-09-8 | 95% | 25g |
$3428 | 2023-09-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-ZW802-250mg |
Methyl 4-acetylpicolinate |
934016-09-8 | 97% | 250mg |
1290CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-ZW802-1g |
Methyl 4-acetylpicolinate |
934016-09-8 | 97% | 1g |
2532.0CNY | 2021-07-12 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-ZW802-100mg |
Methyl 4-acetylpicolinate |
934016-09-8 | 97% | 100mg |
602CNY | 2021-05-08 | |
| Chemenu | CM126552-1g |
methyl 4-acetylpicolinate |
934016-09-8 | 95% | 1g |
$355 | 2021-08-05 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | M93070-5g |
Methyl 4-acetylpicolinate |
934016-09-8 | 5g |
￥8446.0 | 2021-09-04 |
Methyl 4-acetylpicolinate Production Method
Production Method 1
Reaction Conditions
1.1 Catalysts: Palladium diacetate , 1,1-Bis(diphenylphosphino)ferrocene Solvents: Ethanol ; rt; 16 h, 55 °C
Reference
Production Method 2
Reaction Conditions
1.1 Catalysts: Tetrakis(triphenylphosphine)palladium Solvents: 1,4-Dioxane ; 16 h, 100 °C
1.2 Reagents: Hydrochloric acid Solvents: Tetrahydrofuran , Water ; 3 h, rt
1.3 Reagents: Sodium bicarbonate Solvents: Water ; pH 6 - 7, rt
1.2 Reagents: Hydrochloric acid Solvents: Tetrahydrofuran , Water ; 3 h, rt
1.3 Reagents: Sodium bicarbonate Solvents: Water ; pH 6 - 7, rt
Reference
- Preparation of heterocyclic FXR modulators, World Intellectual Property Organization, , ,
Methyl 4-acetylpicolinate Raw materials
Methyl 4-acetylpicolinate Preparation Products
Methyl 4-acetylpicolinate Related Literature
-
Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
-
J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
-
Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
-
Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
-
Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
934016-09-8 (Methyl 4-acetylpicolinate) Related Products
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