Production Method 1

933746-81-7

Reaction Conditions

1.1 Reagents: Tetrabutylammonium fluoride Solvents: Tetrahydrofuran ;  12 h, rt

Reference

Preparation of heterocyclic compds as PAD inhibitors

, World Intellectual Property Organization, , ,

Production Method 2

3093-97-8

933746-81-7

Reaction Conditions

1.1 Reagents: Lithium aluminum hydride Solvents: Tetrahydrofuran ;  0 °C; 0 °C → 25 °C; 3 h, 25 °C; 25 °C → 0 °C
1.2 Reagents: Ammonium chloride Solvents: Water ;  0 °C
1.3 Reagents: Dipyridinium dichromate Solvents: Dichloromethane ;  12 h, 25 °C

Reference

Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility

Tan, Yu Jia; Li, Ming; Gunawan, Gregory Adrian; Nyantakyi, Samuel Agyei; Dick, Thomas; et al, ACS Medicinal Chemistry Letters, 2021, 12(5), 704-712

Production Method 3

884048-32-2

933746-81-7

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Dichloromethane ;  23 h, rt

Reference

Preparation of 2-indoleacrylamide derivatives as TRPV1 receptor function regulators

, Japan, , ,

Production Method 4

884048-32-2

933746-81-7

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Dimethylformamide ;  12 h, rt

Reference

Concise synthesis of carbazole-1,4-quinones and evaluation of their antiproliferative activity against HCT-116 and HL-60 cells

Nishiyama, Takashi; Hatae, Noriyuki; Yoshimura, Teruki; Takaki, Sawa; Abe, Takumi ; et al, European Journal of Medicinal Chemistry, 2016, 121, 561-577

Production Method 5

933746-81-7

Reaction Conditions

1.1 Reagents: Tetrabutylammonium fluoride Solvents: Tetrahydrofuran ;  12 h, rt

Reference

Preparation of imidazo-pyridine compounds as PAD inhibitors

, India, , ,

Production Method 6

884048-32-2

933746-81-7

Reaction Conditions

1.1 Reagents: Manganese oxide (MnO2) Solvents: Dichloromethane ;  rt

Reference

Addition of a Carbene Catalyst to Indole Aryl Aldehyde Activates a Remote δ-sp2 Carbon for Protonation and Formal [4+2] Reaction

, China, , ,

6-Fluoro-1H-indole-2-carbaldehyde Raw materials

• 6-Fluoro-1H-indole-2-carboxylic acid
• (6-fluoro-1H-indol-2-yl)methanol

6-Fluoro-1H-indole-2-carbaldehyde Preparation Products

• 6-Fluoro-1H-indole-2-carbaldehyde (933746-81-7)

• 1. An amplified fluorescence detection of T4 polynucleotide kinase activity based on coupled exonuclease III reaction and a graphene oxide platform?
  Ni-Na Sun,Fengli Qu,Xiaobing Zhang,Shufang Zhang,Jinmao You Analyst, 2015,140, 1827-1831
• 2. Aggregation-induced emission of luminol: a novel strategy for fluorescence ratiometric detection of ALP and As(v) with high sensitivity and selectivity?
  Yuan-Jun Tong,Lu-Dan Yu,Lu-Lu Wu,Shu-Ping Cao,Ru-Ping Liang,Li Zhang,Xing-Hua Xia,Jian-Ding Qiu Chem. Commun., 2018,54, 7487-7490
• 3. Achieving excellent anti-corrosion and tribological performance by tailoring the surface morphology and chemical composition of aluminum alloys
  Wenjie Zhao,Hua Hou,Yuchun Jin,Zhixiang Zeng,Xuedong Wu,Qunji Xue RSC Adv., 2014,4, 60307-60315
• 4. An investigation into the origin of variations in photovoltaic performance using D–D–π–A and D–A–π–A triphenylimidazole dyes with a copper electrolyte?
  Govind Reddy Mol. Syst. Des. Eng., 2021,6, 779-789
• 5. An integrated droplet-digital microfluidic system for on-demand droplet creation, mixing, incubation, and sorting?
  Lab Chip, 2019,19, 524-535

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Indoles

• 19005-93-7(Indole-2-carbaldehyde)
• 457899-31-9(Methanol, 2H-indol-2-ylidene-, (1E)- (9CI))
• 904369-10-4(8-Fluoroquinoline-2-carbaldehyde)
• 904369-25-1(7-fluoroquinoline-2-carbaldehyde)
• 260430-93-1(6-Fluoroquinoline-2-carbaldehyde)
• 1351517-03-7(7,8-Difluoroquinoline-2-carbaldehyde)
• 399-72-4(5-fluoro-2-methyl-1H-indole)
• 40311-13-5(6-Fluoro-2-methyl-1H-indole)
• 1367930-66-2(7-Fluoro-1H-indole-2-carbaldehyde)
• 220943-23-7(5-Fluoro-1H-indole-2-carbaldehyde)