Production Method 1

755027-18-0

932372-99-1

Reaction Conditions

1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  30 min, -10 °C; 1 h, 0 °C; 16 h, rt
1.2 Reagents: Sodium carbonate Solvents: Water

Reference

Preparation of heteroaryl compounds for treating Huntington's disease

, World Intellectual Property Organization, , ,

Production Method 2

755027-18-0

932372-99-1

Reaction Conditions

1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  0 °C; 3 h, 0 °C
1.2 Reagents: Water ;  0 °C

Reference

3-sulfonyloxyaryl(mesityl)iodonium triflates as 1,2-benzdiyne precursors with activation via ortho-deprotonative elimination strategy

Yuan, Haoyin; Yin, Wenhao; Hu, Jili; Li, Yang, Nature Communications, 2023, 14(1),

Production Method 3

755027-18-0

932372-99-1

Reaction Conditions

1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  -78 °C; 1 h, -78 °C; -78 °C → rt; overnight, rt
1.2 Reagents: Water ;  rt

Reference

Nanopatterning by Molecular Polygons

Jester, Stefan-S.; Sigmund, Eva; Hoger, Sigurd, Journal of the American Chemical Society, 2011, 133(29), 11062-11065

Production Method 4

111721-74-5

932372-99-1

Reaction Conditions

1.1 Reagents: Sodium nitrite ,  Sulfuric acid Solvents: Water ;  5 - 10 °C
1.2 Reagents: Sulfuric acid ,  Copper sulfate ;  80 °C

Reference

Industrial preparation method of 2-bromo-5-iodophenol from o-nitroaniline

, China, , ,

Production Method 5

932372-99-1

Reaction Conditions

Reference

Preparation of sulfonamide derivatives as PGD2 receptor antagonists

, World Intellectual Property Organization, , ,

Production Method 6

755027-18-0

932372-99-1

Reaction Conditions

1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  -10 °C; 17 h, -10 °C → rt
1.2 Reagents: Methanol ;  rt; 10 min, rt

Reference

Preparation of heterocyclic nitrogen compounds as NLRP3 inhibitors and antiinflammatory agents

, China, , ,

Production Method 7

755027-18-0

932372-99-1

Reaction Conditions

1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  30 min, < 0 °C; 1 h, 0 °C; 16 h, rt

Reference

Preparation of heterocyclic and heteroaryl compounds for treating Huntington's disease

, World Intellectual Property Organization, , ,

Production Method 8

755027-18-0

932372-99-1

Reaction Conditions

1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  30 min, cooled; 1 h, cooled; 3 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  cooled; 1 h, rt

Reference

Method for producing N-phenyl-N'-phenylsulfonylpiperazine derivative

, World Intellectual Property Organization, , ,

Production Method 9

755027-18-0

932372-99-1

Reaction Conditions

1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  0 °C; 16 h, 0 °C → rt

Reference

Preparation of trifluoromethyl alcohols as modulators of RORγt

, United States, , ,

Production Method 10

932372-99-1

Reaction Conditions

Reference

Preparation of heterocyclic substituted 1,3,4-thiadiazole and pyridazine compounds and methods of using the same

, World Intellectual Property Organization, , ,

Production Method 11

932372-99-1

Reaction Conditions

Reference

Preparation of heteroaryl compounds for treating Huntington's disease

, World Intellectual Property Organization, , ,

2-Bromo-5-iodophenol Raw materials

• 2-Bromo-5-iodoaniline
• 1-bromo-4-iodo-2-methoxybenzene

2-Bromo-5-iodophenol Preparation Products

• 2-Bromo-5-iodophenol (932372-99-1)

• 1. Estimation of activation energy for electroporation and pore growth rate in liquid crystalline and gel phases of lipid bilayers using molecular dynamics simulations?
  Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640
• 2. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
  Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
• 3. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 4. Fe3O4@PANI: a magnetic polyaniline nanomaterial for highly efficient and handy enrichment of intact N-glycopeptides??
  Zhizhen Lai,Mo Zhang,Jinyu Zhou,Tianjing Chen,Dan Li,Xuejing Shen,Jia Liu,Jiang Zhou,Zhili Li Analyst, 2021,146, 4261-4267
• 5. Fe3O4 nanosphere@microporous organic networks: enhanced anode performances in lithium ion batteries through carbonization?
  Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726

• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenols Halophenols Bromophenols

• 216306-47-7(1,4-Benzenediol, 2-bromo-5-iodo-)
• 89466-01-3(Phenol, 2-bromo-4,6-diiodo-)
• 133430-98-5(2-Bromo-4-iodophenol)
• 755027-18-0(1-bromo-4-iodo-2-methoxybenzene)
• 2040-86-0(2-Bromo-6-iodophenol)
• 182056-39-9(2-Bromo-4-iodoanisole)
• 570391-20-7(3-Bromo-5-iodophenol)
• 202865-84-7(4-bromo-3-iodoPhenol)
• 53872-06-3(PHENOL, 2,4-DIBROMO-6-IODO-)
• 863870-88-6(2-Bromo-3-iodophenol)