Production Method 1

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: 1,2-Dibromoethane Solvents: Tetrahydrofuran ;  rt; 10 min, reflux; 1 h, reflux

Reference

Pushing steric limits in osmium(IV) tetraaryl complexes

Parr, Joseph M.; Olivar, Clarissa; Saal, Thomas; Haiges, Ralf; Inkpen, Michael S., Dalton Transactions, 2022, 51(27), 10558-10570

Production Method 2

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Solvents: 1,2-Dibromoethane ,  Tetrahydrofuran ;  rt; 10 min, reflux; 1 h, reflux

Reference

An improved route to osmium(IV) tetraaryl complexes

Parr, Joseph M.; Haiges, Ralf; Inkpen, Michael S., ChemRxiv, 2020, 1, 1-11

Production Method 3

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran ;  rt; 2 h, rt

Reference

Bimetallic tandem catalysis-enabled enantioselective cycloisomerization/carbonyl-ene reaction for construction of 5-oxazoylmethyl α-silyl alcohol

Sang, Xinpeng; Mo, Yuhao; Li, Shiya; Liu, Xiaohua; Cao, Weidi; et al, Chemical Science, 2023, 14(31), 8315-8320

Production Method 4

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran ;  rt; 3 h, rt

Reference

Synthesis of Sulfur-Containing Oxindoles by Photoinduced Alkene Difunctionalization via Sulfur 1,2-Relocation

Lu, Cong; Chen, Rui; Wang, Rui; Jing, Dong; Zheng, Ke, Organic Letters, 2023, 25(5), 750-755

Production Method 5

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran ;  3 h

Reference

Redox-neutral access to 3,3'-disubstituted oxindoles via radical coupling reactions

Lu, Cong; Jing, Dong; Shen, Yanling; Luo, Jiajing; Zheng, Ke, Organic Chemistry Frontiers, 2022, 9(15), 4164-4170

Production Method 6

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  reflux

Reference

Ultralong room temperature phosphorescence and ultraviolet fluorescence from simple triarylphosphine oxides

Jena, Satyam; Munthasir, Akkarakkaran Thayyil Muhammed; Thilagar, Pakkirisamy, Journal of Materials Chemistry C: Materials for Optical and Electronic Devices, 2022, 10(23), 9124-9131

Production Method 7

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  rt; 30 min, rt; 1 h, reflux; cooled

Reference

Diastereodivergent synthesis of chromeno[2,3-b]chromenes by tuning all of the reactivity centers of isocyanoacetate

Wang, Lei; Huang, Zitong; Guo, Xiaoyu; Liu, Jian; Dong, Jinhuan; et al, Chemical Communications (Cambridge, 2022, 58(44), 6433-6436

Production Method 8

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium ,  Lithium chloride Solvents: Tetrahydrofuran ;  rt; 15 - 30 min, rt

Reference

A Convenient Synthesis of Benzonitriles via Electrophilic Cyanation with N-Cyanobenzimidazole

Anbarasan, Pazhamalai; Neumann, Helfried; Beller, Matthias, Chemistry - A European Journal, 2010, 16(16), 4725-4728

Production Method 9

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: 1,2-Dibromoethane Solvents: Diethyl ether ;  2 min, heated; 3 h, 0 °C; 30 min, 0 °C

Reference

Synthesis of Bicyclo[1.1.1]pentane Bioisosteres of Internal Alkynes and para-Disubstituted Benzenes from [1.1.1]Propellane

Makarov, Ilya S.; Brocklehurst, Cara E.; Karaghiosoff, Konstantin; Koch, Guido; Knochel, Paul, Angewandte Chemie, 2017, 56(41), 12774-12777

Production Method 10

932-31-0

Reaction Conditions

1.1 Reagents: 1,2-Dibromoethane ,  Magnesium Solvents: Tetrahydrofuran ;  rt; 1 h, rt

Reference

Dual nickel photocatalysis for O-aryl carbamate synthesis from carbon dioxide

Sahari, Aleksi ; Puumi, Jukka ; Mannisto, Jere K. ; Repo, Timo, Journal of Organic Chemistry, 2023, 88(6), 3822-3829

Production Method 11

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran ;  3 h, rt → 70 °C

Reference

Synthesis of Chiral Diarylmethylamines by Cobalt-Catalyzed Enantioselective C-H Alkoxylation

Wang, Zhen-Kai; Wu, Yong-Jie; Yao, Qi-Jun; Shi, Bing-Feng, Angewandte Chemie, 2023, 62(28),

Production Method 12

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Diethyl ether ,  Tetrahydrofuran ;  rt; rt → 50 °C

Reference

Enantioselective Synthesis of Chiral Cyclic Hydrazines by Ni-Catalyzed Asymmetric Hydrogenation

Wang, Siwei; Xie, Chaochao; Zhu, Yu; Zi, Guofu ; Zhang, Zhanbin; et al, Organic Letters, 2023, 25(20), 3644-3648

Production Method 13

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  heated; 2 h, reflux

Reference

Asymmetric hydrogenation of 1,1-diarylethylenes and benzophenones through a relay strategy

Li, Ke; Wu, Wen-Qiang; Lin, Yunzhi; Shi, Hang, Nature Communications, 2023, 14(1),

Production Method 14

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran

Reference

Tris(pentafluorophenyl)borane-Catalyzed Stereospecific Bromocyanation of Styrene Derivatives with Cyanogen Bromide

Kiyokawa, Kensuke ; Noguchi, Ikumi; Nagata, Takaya; Minakata, Satoshi, Organic Letters, 2023, 25(14), 2537-2542

Production Method 15

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Solvents: 1,2-Dibromoethane ,  Tetrahydrofuran ;  rt; 1 h, 40 °C

Reference

Asymmetric Synthesis of Chiral Sulfimides through the O-Alkylation of Enantioenriched Sulfinamides and Addition of Carbon Nucleophiles

Tsuzuki, Saori; Kano, Taichi, Angewandte Chemie, 2023, 62(16),

Production Method 16

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  0 °C; 1 h, 0 °C; 0 °C → rt; overnight, rt

Reference

Carbonylative Co- and Terpolymerizations of 10-Undecen-1-ol: A Route to Polyketoesters with Tunable Compositions

Lo, Shao-Yu; Folster, Carlton P.; Harkins, Robin P. ; Anderson, Ryan J.; Lien, Yu-Ling; et al, ACS Catalysis, 2022, 12(23), 14629-14636

Production Method 17

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran ;  rt; 20 min, reflux; 6 h, reflux

Reference

Enantioselective Construction of Sila-bicyclo[3.2.1] Scaffolds Bearing Both Carbon- and Silicon-Stereocenters

Yin, Kai-Lin; Zhao, Shuang; Qin, Ying; Chen, Shu-Han; Li, Bo; et al, ACS Catalysis, 2022, 12(22), 13999-14005

Production Method 18

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran ;  2 min, rt
1.2 Solvents: Tetrahydrofuran ;  3 h, rt; 30 min, rt

Reference

Visible-Light-Induced Aerobic Oxidation of Tertiary Silanes to Silanols using Molecular Oxygen as an Oxidant

He, Pei; Zhang, Fengmei; Si, Xiaoxi; Jiang, Wei; Shen, Qinpeng; et al, Synthesis, 2023, 55(5), 765-772

Production Method 19

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium ,  Iodine Solvents: Tetrahydrofuran ;  rt; 1 h, rt

Reference

Silylium-Ion-Promoted Skeletal Reorganization of β-Silylated Cyclopropanes Bearing an Allyl Group at the Silicon Atom Coupled with Intermolecular Formation of a Quaternary Carbon Atom

Long, Peng-Wei ; Wang, Guoqiang ; Klare, Hendrik F. T. ; Oestreich, Martin, ACS Catalysis, 2022, 12(19), 12310-12314

Production Method 20

932-31-0

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran ;  heated; reflux

Reference

Direct Synthesis of Biphenyl-2-carbonitriles by Rh(III)-Catalyzed C-H Hiyama Cross-Coupling in Water

Zhang, Xiuqi; Zhang, Fukuan; Li, Xiaolan; Lu, Ming-Zhu ; Meng, Xin; et al, Organic Letters, 2022, 24(28), 5029-5033

2-Tolylmagnesium Bromide Preparation Products

• 2-Tolylmagnesium Bromide (932-31-0)

• 1. Exceptionally high temperature spin crossover in amide-functionalised 2,6-bis(pyrazol-1-yl)pyridine iron(ii) complex revealed by variable temperature Raman spectroscopy and single crystal X-ray diffraction?
  Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
• 2. Emerging investigator series: kinetics of diopside reactivity for carbon mineralization in mafic–ultramafic rocks
  BrianaAguila,LandonHardee,H.ToddSchaef,SiavashZare,MohammadJavadAbdolhosseiniQomi,JarrodV.Crum,JadeE.HollimanJr.,ElenaTajueloRodriguez,LawrenceM.Anovitz,KevinM.Rosso,QuinR.S.Miller
• 3. Emulsion technologies for multicellular tumour spheroid radiation assays?
  Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
• 4. Excellent peroxidase mimicking property of CuO/Pt nanocomposites and their application as an ascorbic acid sensor?
  Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
• 5. Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers?
  Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182

• Other Chemical Reagents Organic Metal Reagents

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)