Cas no 931407-27-1 (Mycophenolic Acid Carboxybutoxy Ether)

Mycophenolic Acid Carboxybutoxy Ether is a chemically modified derivative of mycophenolic acid (MPA), designed to enhance solubility and bioavailability. This ether derivative features a carboxybutoxy side chain, which improves its physicochemical properties while retaining the immunosuppressive activity of the parent compound. It acts as a selective, noncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH), a key enzyme in the de novo purine synthesis pathway, thereby inhibiting lymphocyte proliferation. The structural modification allows for better formulation flexibility and potential applications in targeted drug delivery systems. Its enhanced stability and controlled release profile make it a promising candidate for further pharmaceutical development, particularly in immunosuppressive therapies.
Mycophenolic Acid Carboxybutoxy Ether structure
931407-27-1 structure
Product Name:Mycophenolic Acid Carboxybutoxy Ether
CAS No:931407-27-1
MF:C22H28O8
MW:420.452927589417
CID:1059898
PubChem ID:71750878
Update Time:2025-07-02

Mycophenolic Acid Carboxybutoxy Ether Chemical and Physical Properties

Names and Identifiers

    • Mycophenolic Acid Carboxybutoxy Ether
    • (E)-6-[4-(4-carboxybutoxy)-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl]-4-methylhex-4-enoic acid
    • MPAC
    • Mycophenolic Acid Ca
    • (4E)-6-[4-(4-Carboxybutoxy)-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoic acid
    • 931407-27-1
    • DTXSID10858155
    • (4E)-6-[4-(4-Carboxybutoxy)-1,3-dihydro-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl]-4-methyl-4-hexenoic Acid; MPAC;
    • Inchi: 1S/C22H28O8/c1-13(8-10-18(25)26)7-9-15-20(28-3)14(2)16-12-30-22(27)19(16)21(15)29-11-5-4-6-17(23)24/h7H,4-6,8-12H2,1-3H3,(H,23,24)(H,25,26)/b13-7+
    • InChI Key: PFECETFRFNZFKJ-NTUHNPAUSA-N
    • SMILES: O(CCCCC(=O)O)C1=C(C/C=C(\C)/CCC(=O)O)C(=C(C)C2COC(C=21)=O)OC

Computed Properties

  • Exact Mass: 420.17800
  • Monoisotopic Mass: 420.17841785g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 8
  • Heavy Atom Count: 30
  • Rotatable Bond Count: 12
  • Complexity: 643
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.2
  • Topological Polar Surface Area: 119?2

Experimental Properties

  • PSA: 119.36000
  • LogP: 3.66130

Mycophenolic Acid Carboxybutoxy Ether Pricemore >>

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Additional information on Mycophenolic Acid Carboxybutoxy Ether

Comprehensive Overview of Mycophenolic Acid Carboxybutoxy Ether (CAS No. 931407-27-1): Properties, Applications, and Research Insights

Mycophenolic Acid Carboxybutoxy Ether (CAS No. 931407-27-1) is a chemically modified derivative of mycophenolic acid, a well-known immunosuppressive agent. This compound has garnered significant attention in pharmaceutical research due to its potential applications in drug delivery systems and targeted therapies. The carboxybutoxy ether modification enhances the solubility and bioavailability of the parent compound, making it a promising candidate for advanced therapeutic formulations.

In recent years, the demand for Mycophenolic Acid Carboxybutoxy Ether has surged, driven by its role in the development of next-generation immunosuppressants. Researchers are particularly interested in its ability to modulate immune responses with reduced side effects compared to traditional therapies. This aligns with the growing trend of personalized medicine, where patients seek treatments tailored to their specific needs. The compound's unique chemical structure, characterized by the carboxybutoxy ether side chain, allows for precise control over drug release kinetics, a feature highly valued in modern pharmacology.

The synthesis of Mycophenolic Acid Carboxybutoxy Ether involves a series of carefully controlled reactions to ensure high purity and yield. Analytical techniques such as HPLC and NMR are routinely employed to verify the compound's identity and quality. These methods are critical for meeting regulatory standards, especially in the pharmaceutical industry where consistency and safety are paramount. The CAS No. 931407-27-1 serves as a unique identifier, facilitating accurate documentation and traceability in research and commercial applications.

One of the most frequently asked questions about Mycophenolic Acid Carboxybutoxy Ether pertains to its mechanism of action. Studies suggest that it inhibits inosine monophosphate dehydrogenase (IMPDH), an enzyme essential for purine synthesis in lymphocytes. This selective inhibition makes it a valuable tool for managing autoimmune diseases and preventing organ transplant rejection. The compound's carboxybutoxy ether moiety further enhances its pharmacokinetic profile, ensuring sustained therapeutic effects with minimal toxicity.

Another area of interest is the compound's potential in combination therapies. With the rise of multidrug-resistant pathogens and complex chronic conditions, researchers are exploring synergistic effects between Mycophenolic Acid Carboxybutoxy Ether and other bioactive molecules. Such combinations could revolutionize treatment protocols, offering improved efficacy and patient outcomes. This aligns with the broader healthcare trend of integrating multiple therapeutic modalities to address multifaceted diseases.

From an industrial perspective, the scalability of Mycophenolic Acid Carboxybutoxy Ether production is a key consideration. Advances in green chemistry and continuous flow synthesis have enabled more efficient and environmentally friendly manufacturing processes. These innovations not only reduce production costs but also minimize waste, contributing to sustainable pharmaceutical development. The compound's CAS No. 931407-27-1 is often referenced in patents and technical literature, underscoring its commercial and scientific significance.

In conclusion, Mycophenolic Acid Carboxybutoxy Ether (CAS No. 931407-27-1) represents a cutting-edge advancement in medicinal chemistry. Its unique properties, coupled with its potential for diverse applications, make it a focal point of contemporary research. As the healthcare landscape continues to evolve, this compound is poised to play a pivotal role in shaping the future of immunotherapy and precision medicine. Researchers and industry professionals alike are encouraged to explore its full potential, leveraging its carboxybutoxy ether functionality to develop innovative solutions for unmet medical needs.

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