Production Method 1

93138-61-5

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Ethanol ,  Water ;  reflux

Reference

Synthesis of N-substituted pyrrolidinemethanamine

Wang, Xue-tao; Ge, Min, Huaxue Shiji, 2010, 32(11), 986-988

Production Method 2

116041-19-1

93138-61-5

Reaction Conditions

1.1 Reagents: Lithium aluminum hydride Solvents: Tetrahydrofuran ;  cooled; 1.5 h, reflux; cooled
1.2 Reagents: Potassium sodium tartrate Solvents: Water ;  cooled

Reference

Preparation of novel mutilin derivatives as antibacterial agents

, World Intellectual Property Organization, , ,

Production Method 3

10603-52-8

93138-61-5

Reaction Conditions

1.1 Reagents: Lithium aluminum hydride Solvents: Tetrahydrofuran ;  0 °C → rt; 18 h, rt

Reference

Preparation of indole, azaindole and related heterocyclic pyrrolidine derivatives as antiviral agents

, World Intellectual Property Organization, , ,

Production Method 4

93138-61-5

Reaction Conditions

Reference

Preparation of N-pyrrolidinylmethylalkanoamides and analogs as CCR-3 receptor antagonists

, Germany, , ,

Production Method 5

93138-61-5

Reaction Conditions

Reference

Synthesis and pharmacological evaluation of carboxamide derivatives as selective serotoninergic 5-HT4 receptor agonists

Itoh, Katsuhiko; Kanzaki, Koji; Ikebe, Tsuguo; Kuroita, Takanobu; Tomozane, Hideo; et al, European Journal of Medicinal Chemistry, 1999, 34(11), 977-989

Production Method 6

116041-19-1

93138-61-5

Reaction Conditions

1.1 Reagents: Lithium aluminum hydride Solvents: Tetrahydrofuran ;  3 h, 50 °C; cooled
1.2 Reagents: Ammonium chloride Solvents: Water
1.3 Reagents: Sodium hydroxide Solvents: Ethyl acetate ,  Water ;  20 min

Reference

Preparation of tartaric acid functional compounds for the treatment of disorders mediated by MMPs, aggrecanase, ADMP, LpxC, ADAMs, TACE and TNF-α

, United States, , ,

Production Method 7

218293-49-3

93138-61-5

Reaction Conditions

1.1 Reagents: Triphenylphosphine ,  Water Solvents: Tetrahydrofuran ;  24 h, rt → reflux

Reference

Preparation of pyrimidines and related compounds as alpha 1a adrenergic receptor antagonists

, World Intellectual Property Organization, , ,

Production Method 8

93138-61-5

Reaction Conditions

Reference

Preparation of tartaric acid functional compounds for the treatment of inflammatory disorders mediated by MMPs, aggrecanase, ADMP, LpxC, ADAMs, TACE and TNF-α

, United States, , ,

Production Method 9

93138-61-5

Reaction Conditions

Reference

Preparation of tartaric acid functional compounds for the treatment of inflammatory disorders

, World Intellectual Property Organization, , ,

Production Method 10

93138-61-5

Reaction Conditions

Reference

1-(Heteroaryl)-azetidines and -pyrrolidines as 5-HT3 receptor agonists

, European Patent Organization, , ,

(1-benzylpyrrolidin-3-yl)methanamine Raw materials

• 1-Benzylpyrrolidine-3-carbonitrile
• 3-(Azidomethyl)-1-benzylpyrrolidine
• 1-benzyl-5-oxopyrrolidine-3-carboxamide

(1-benzylpyrrolidin-3-yl)methanamine Preparation Products

• (1-benzylpyrrolidin-3-yl)methanamine (93138-61-5)

• 1. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
  Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
• 2. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
• 3. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
• 4. Fc microparticles can modulate the physical extent and magnitude of complement activity?
  David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
• 5. Fe/S-Catalyzed synthesis of 2-benzoylbenzoxazoles and 2-quinolylbenzoxazoles via redox condensation of o-nitrophenols with acetophenones and methylquinolines?
  Thi Thu Tram Nguyen,Thanh Binh Nguyen Org. Biomol. Chem., 2021,19, 6015-6020

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylmethylamines
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides
• Solvents and Organic Chemicals Organic Compounds

• 86732-22-1(2-benzyl-octahydropyrrolo3,4-cpyrrole)
• 1220023-77-7(Benzyl-methyl-pyrrolidin-3-ylmethyl-amine)
• 172139-04-7(cis-2-Benzyloctahydropyrrolo[3,4-c]pyrrole)
• 165894-00-8(2,5-Dibenzyl-hexahydropyrrolo3,4-cpyrrole)
• 229323-04-0(3-Pyrrolidinemethanamine,1-(phenylmethyl)-, (3R)-)
• 91189-07-0((1-benzylpyrrolidin-3-ylmethyl)ethylamine)
• 1220176-25-9(Benzyl-ethyl-pyrrolidin-3-ylmethyl-amine)
• 172739-04-7(cis-5-benzyl-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrole)
• 229323-07-3((S)-3-Aminomethyl-1-benzylpyrrolidine)
• 91189-05-8(1-(1-benzylpyrrolidin-3-yl)-N-methyl-methanamine)