- Rational Design of Calpain Inhibitors Based on Calpastatin PeptidomimeticsLow, Kristin E.; Ler, Spencer; Chen, Kevin J.; Campbell, Robert L.; Hickey, Jennifer L.; et al, Journal of Medicinal Chemistry, 2016, 59(11), 5403-5415
Cas no 92944-71-3 (4-(Maleimido)benzophenone)
4-(Maleimido)benzophenone structure
Product Name:4-(Maleimido)benzophenone
CAS No:92944-71-3
MF:C17H11NO3
MW:277.274144411087
MDL:MFCD00079465
CID:807060
PubChem ID:57654429
Update Time:2024-10-26
4-(Maleimido)benzophenone Chemical and Physical Properties
Names and Identifiers
-
- 1H-Pyrrole-2,5-dione,1-(4-benzoylphenyl)-
- 4-(Maleimido)benzophenone
- 1-(4-Benzoylphenyl)-1H-pyrrole-2,5-dione
- 1-(4-benzoylphenyl)pyrrole-2,5-dione
- 4-(Maleimido)benzoph
- Benzophenone-4-maleimide [4-(N-Maleimido)benzophenone]
- 1-(4-Benzoylphenyl)-1H-pyrrole-2,5-dione (ACI)
- N-(4-Benzoylphenyl)maleimide
- N-(p-Phenylcarbonylphenyl)maleimide
- M3259
- Benzophenone-4-maleimide
- OZIZEXQRIOURIJ-UHFFFAOYSA-N
- DTXSID50239207
- 4-Maleimidobenzophenone
- AKOS004115282
- 92944-71-3
- 1H-Pyrrole-2,5-dione, 1-(4-benzoylphenyl)-
- DTXCID30161698
- 1-(4-Benzoylphenyl)-1H-pyrrole-2,5-dione; N-(4-Benzoylphenyl)maleimide;
- MFCD00079465
- CS-0117778
- SCHEMBL339889
- BS-49340
- DB-057349
- E79368
- 4-(N-Maleimido)benzophenone
-
- MDL: MFCD00079465
- Inchi: 1S/C17H11NO3/c19-15-10-11-16(20)18(15)14-8-6-13(7-9-14)17(21)12-4-2-1-3-5-12/h1-11H
- InChI Key: OZIZEXQRIOURIJ-UHFFFAOYSA-N
- SMILES: O=C1N(C2C=CC(C(C3C=CC=CC=3)=O)=CC=2)C(=O)C=C1
Computed Properties
- Exact Mass: 277.07400
- Monoisotopic Mass: 277.074
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 21
- Rotatable Bond Count: 3
- Complexity: 450
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.4
- Topological Polar Surface Area: 54.4A^2
Experimental Properties
- Density: 1.33
- Melting Point: 155-157°C
- Boiling Point: 472.9°Cat760mmHg
- Flash Point: 223.7°C
- Refractive Index: 1.651
- Solubility: chloroform: 50?mg/mL
- PSA: 54.45000
- LogP: 2.41200
4-(Maleimido)benzophenone Security Information
-
Symbol:
- Signal Word:Warning
- Hazard Statement: H315-H319-H335
- Warning Statement: P261-P305+P351+P338
- Hazardous Material transportation number:NONH for all modes of transport
- WGK Germany:3
- Hazard Category Code: 36/37/38
- Safety Instruction: S26; S36
-
Hazardous Material Identification:
- Risk Phrases:R36/37/38
- Storage Condition:2-8°C
4-(Maleimido)benzophenone Customs Data
- HS CODE:2925190090
- Customs Data:
China Customs Code:
2925190090Overview:
2925190090 Other imides and their derivative salts. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
4-(Maleimido)benzophenone Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | M3259-50MG |
4-(Maleimido)benzophenone |
92944-71-3 | 98.0%(GC) | 50MG |
¥1100.0 | 2022-09-28 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | M3259-250MG |
4-(Maleimido)benzophenone |
92944-71-3 | 98.0%(GC) | 250MG |
¥3750.0 | 2022-09-28 | |
| BAI LING WEI Technology Co., Ltd. | 350731-25MG |
4-(N-Maleimido)benzophenone, 98% |
92944-71-3 | 98% | 25MG |
¥ 699 | 2022-04-26 | |
| BAI LING WEI Technology Co., Ltd. | 350731-100MG |
4-(N-Maleimido)benzophenone, 98% |
92944-71-3 | 98% | 100MG |
¥ 1746 | 2022-04-26 | |
| BAI LING WEI Technology Co., Ltd. | 350731-500MG |
4-(N-Maleimido)benzophenone, 98% |
92944-71-3 | 98% | 500MG |
¥ 5762 | 2022-04-26 | |
| TRC | M133000-25mg |
4-(Maleimido)benzophenone |
92944-71-3 | 25mg |
$ 121.00 | 2023-09-07 | ||
| TRC | M133000-50mg |
4-(Maleimido)benzophenone |
92944-71-3 | 50mg |
$ 138.00 | 2023-09-07 | ||
| TRC | M133000-100mg |
4-(Maleimido)benzophenone |
92944-71-3 | 100mg |
$ 167.00 | 2023-09-07 | ||
| TRC | M133000-250mg |
4-(Maleimido)benzophenone |
92944-71-3 | 250mg |
$391.00 | 2023-05-18 | ||
| TRC | M133000-500mg |
4-(Maleimido)benzophenone |
92944-71-3 | 500mg |
$758.00 | 2023-05-18 |
4-(Maleimido)benzophenone Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Acetic anhydride , Sodium acetate
Reference
Production Method 2
Reaction Conditions
1.1 Solvents: Toluene ; 3 h, reflux
1.2 Reagents: Sodium acetate Solvents: Acetic anhydride ; 2 h, reflux
1.3 Reagents: Sodium bicarbonate ; neutralized
1.2 Reagents: Sodium acetate Solvents: Acetic anhydride ; 2 h, reflux
1.3 Reagents: Sodium bicarbonate ; neutralized
Reference
- Synthesis and characterization of styrene/maleimide copolymers with high poling stability of dipolar chromophoreArora, S.; Kumar, S., Optoelectronics and Advanced Materials, 2009, 3(12), 1359-1364
Production Method 3
Reaction Conditions
1.1 Solvents: Diethyl ether ; 1 h, reflux
1.2 Reagents: Sodium acetate Solvents: Acetic anhydride ; 0.5 h, 90 °C
1.3 Reagents: Water ; cooled
1.2 Reagents: Sodium acetate Solvents: Acetic anhydride ; 0.5 h, 90 °C
1.3 Reagents: Water ; cooled
Reference
- Design, synthesis and biochemical evaluation of novel ethanoanthracenes and related compounds to target Burkitt's lymphomaByrne, Andrew J.; Bright, Sandra A.; McKeown, James P.; O'Brien, John E.; Twamley, Brendan; et al, Pharmaceuticals, 2020, 13(1),
Production Method 4
Reaction Conditions
Reference
- Synthesis of new bifunctional maleimide compounds for the preparation of chemoimmunoconjugatesBeyer, U.; Kruger, M.; Schumacher, P.; Unger, C.; Kratz, F., Monatshefte fuer Chemie, 1997, 128(1), 91-102
Production Method 5
Production Method 6
Reaction Conditions
1.1 Solvents: Diethyl ether ; rt; rt → reflux; 8 h, reflux
1.2 Reagents: Acetic anhydride , Sodium acetate ; 5 h, 80 °C
1.2 Reagents: Acetic anhydride , Sodium acetate ; 5 h, 80 °C
Reference
- Through-Space Charge-Transfer Thermally Activated Delayed Fluorescence Alternating Donor-Acceptor Copolymers for Nondoped Solution-Processable OLEDsBelousov, George K.; Vaitusionak, Aliaksei A.; Vasilenko, Irina V.; Ghasemi, Melika ; Andruleviciene, Viktorija; et al, Macromolecules (Washington, 2023, 56(7), 2686-2699
Production Method 7
Reaction Conditions
Reference
- Reaction of acyl chlorides with N-phenylimides of maleic and itaconic acidsSanzhizhapov, D. B.; Mognonov, D. M.; Khakhinov, V. V.; Radnaeva, L. D.; Erdyneev, N. S., Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, 1984, (4), 118-20
Production Method 8
Reaction Conditions
1.1 Reagents: Acetic anhydride , Sodium acetate ; 30 min, 95 °C; 95 °C → rt
1.2 Solvents: Water ; 30 min, cooled
1.2 Solvents: Water ; 30 min, cooled
Reference
- Effect of Polymerizable Photoinitiators on the UV-polymerization behaviors of photosensitive polysiloxaneJiang, Bo; Zhang, Tong; Zhao, Liwei; Xu, Zhiming; Huang, Yudong, Journal of Polymer Science, 2017, 55(10), 1696-1705
Production Method 9
Reaction Conditions
Reference
- Antineoplastic cytotoxic agent conjugates with transferrin, albumin and polyethylene glycol, World Intellectual Property Organization, , ,
Production Method 10
Reaction Conditions
Reference
- Antineoplastic transferrin and albumin conjugates of cytostatic compounds selected from anthracyclines, alkylating agents, antimetabolites, and cisplatin analogs, Germany, , ,
4-(Maleimido)benzophenone Raw materials
- 4-aminobenzophenone
- N-Phenylmaleimide
- 2,5-dihydrofuran-2,5-dione
- Benzoyl chloride
- 2-Butenoic acid, 4-[(4-benzoylphenyl)amino]-4-oxo-
4-(Maleimido)benzophenone Preparation Products
4-(Maleimido)benzophenone Related Literature
-
Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
-
Zhizhen Lai,Mo Zhang,Jinyu Zhou,Tianjing Chen,Dan Li,Xuejing Shen,Jia Liu,Jiang Zhou,Zhili Li Analyst, 2021,146, 4261-4267
-
Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761
-
Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
-
Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
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