- Expedite Protocol for Construction of Chiral Regioselectively N-Protected Monosubstituted Piperazine, 1,4-Diazepane, and 1,4-Diazocane Building BlocksCrestey, Francois; Witt, Matthias; Jaroszewski, Jerzy W.; Franzyk, Henrik, Journal of Organic Chemistry, 2009, 74(15), 5652-5655
Cas no 928025-62-1 (tert-butyl (3R)-3-(2-methylpropyl)piperazine-1-carboxylate)
928025-62-1 structure
Product Name:tert-butyl (3R)-3-(2-methylpropyl)piperazine-1-carboxylate
CAS No:928025-62-1
MF:C13H26N2O2
MW:242.357743740082
MDL:MFCD07772108
CID:803213
PubChem ID:24820548
Update Time:2024-10-26
tert-butyl (3R)-3-(2-methylpropyl)piperazine-1-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- (S)-tert-Butyl 3-isobutylpiperazine-1-carboxylate
- (S)-1-Boc-3-isobutyl-piperazine
- 1-Piperazinecarboxylic acid, 3-(2-methylpropyl)-, 1,1-dimethylethyl ester, (3S)-
- 1,1-Dimethylethyl (3S)-3-(2-methylpropyl)-1-piperazinecarboxylate (ACI)
- tert-butyl (3R)-3-(2-methylpropyl)piperazine-1-carboxylate
- MFCD07772108
- tert-butyl (3S)-3-isobutylpiperazine-1-carboxylate
- STL555215
- F52933
- tert-Butyl (3S)-3-(2-methylpropyl)piperazine-1-carboxylate
- (S)-tert-butyl3-isobutylpiperazine-1-carboxylate
- LSZJZDBPJNYEIE-NSHDSACASA-N
- DB-002993
- (S)-1-BOC-3-ISOBUTYLPIPERAZINE
- MS-20214
- t-Butyl (3S)-3-(2-methylpropyl)piperazine-1-carboxylate
- 1-Piperazinecarboxylicacid,3-(2-methylpropyl)-,1,1-dimethylethyl ester,(3S)-
- DTXSID30647563
- J-502365
- SCHEMBL10219117
- BBL101419
- 928025-62-1
- AKOS005258455
- tert-butyl (S)-3-isobutylpiperazine-1-carboxylate
-
- MDL： MFCD07772108
- Inchi： 1S/C13H26N2O2/c1-10(2)8-11-9-15(7-6-14-11)12(16)17-13(3,4)5/h10-11,14H,6-9H2,1-5H3/t11-/m0/s1
- InChI Key： LSZJZDBPJNYEIE-NSHDSACASA-N
- SMILES： C(N1CCN[C@@H](CC(C)C)C1)(=O)OC(C)(C)C
Computed Properties
- Exact Mass: 242.199
- Monoisotopic Mass: 242.199
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 17
- Rotatable Bond Count: 4
- Complexity: 259
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 41.6A^2
- XLogP3: 2.2
Experimental Properties
- Density: 0.962
- Boiling Point: 315.5°Cat760mmHg
- Flash Point: 144.6°C
- Refractive Index: 1.458
- PSA: 41.57000
- LogP: 2.50810
tert-butyl (3R)-3-(2-methylpropyl)piperazine-1-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FB02633-1g |
Tert-butyl (3s)-3-(2-methylpropyl)piperazine-1-carboxylate |
928025-62-1 | 95% | 1g |
$609 | 2023-09-07 | |
| TRC | B663733-50mg |
(S)-1-Boc-3-isobutyl-piperazine |
928025-62-1 | 50mg |
$ 50.00 | 2022-06-07 | ||
| TRC | B663733-100mg |
(S)-1-Boc-3-isobutyl-piperazine |
928025-62-1 | 100mg |
$ 70.00 | 2022-06-07 | ||
| TRC | B663733-500mg |
(S)-1-Boc-3-isobutyl-piperazine |
928025-62-1 | 500mg |
$ 295.00 | 2022-06-07 | ||
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FB02633-5g |
Tert-butyl (3s)-3-(2-methylpropyl)piperazine-1-carboxylate |
928025-62-1 | 95 | 5g |
$670 | 2021-05-11 | |
| abcr | AB495435-1 g |
t-Butyl (3S)-3-(2-methylpropyl)piperazine-1-carboxylate; . |
928025-62-1 | 1g |
€435.80 | 2023-04-19 | ||
| Chemenu | CM130227-1g |
tert-butyl (S)-3-isobutylpiperazine-1-carboxylate |
928025-62-1 | 95% | 1g |
$*** | 2023-05-29 | |
| Chemenu | CM130227-1g |
tert-butyl (S)-3-isobutylpiperazine-1-carboxylate |
928025-62-1 | 95% | 1g |
$299 | 2021-08-05 | |
| Chemenu | CM130227-5g |
tert-butyl (S)-3-isobutylpiperazine-1-carboxylate |
928025-62-1 | 95% | 5g |
$898 | 2021-08-05 | |
| Alichem | A139002852-1g |
(S)-tert-Butyl 3-isobutylpiperazine-1-carboxylate |
928025-62-1 | 95% | 1g |
$339.20 | 2023-08-31 |
tert-butyl (3R)-3-(2-methylpropyl)piperazine-1-carboxylate Production Method
Production Method 1
Reaction Conditions
1.1 Solvents: 1,2-Dichloroethane ; 60 min, 40 °C
1.2 Reagents: Triethylamine Solvents: Acetonitrile ; 3 h, rt
1.3 Reagents: Triphenylphosphine Solvents: Tetrahydrofuran ; 5 min, rt
1.4 Reagents: Diisopropyl azodicarboxylate ; 3.5 h, rt
1.5 Reagents: 1-Octanethiol , 1,8-Diazabicyclo[5.4.0]undec-7-ene Solvents: Acetonitrile ; 15 min, rt
1.2 Reagents: Triethylamine Solvents: Acetonitrile ; 3 h, rt
1.3 Reagents: Triphenylphosphine Solvents: Tetrahydrofuran ; 5 min, rt
1.4 Reagents: Diisopropyl azodicarboxylate ; 3.5 h, rt
1.5 Reagents: 1-Octanethiol , 1,8-Diazabicyclo[5.4.0]undec-7-ene Solvents: Acetonitrile ; 15 min, rt
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Triethylamine Solvents: Acetonitrile ; cooled; 17 h, rt
Reference
- Preparation of piperazinyl benzothiazoles as HDL increasing agents, Japan, , ,
Production Method 3
Reaction Conditions
Reference
- Preparation of benzothiazole derivatives and other heterocyclic compounds as PPAR agonists, World Intellectual Property Organization, , ,
tert-butyl (3R)-3-(2-methylpropyl)piperazine-1-carboxylate Raw materials
tert-butyl (3R)-3-(2-methylpropyl)piperazine-1-carboxylate Preparation Products
tert-butyl (3R)-3-(2-methylpropyl)piperazine-1-carboxylate Related Literature
-
Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
-
Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
-
J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
-
Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
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