Production Method 1

56-81-5

60811-17-8

927800-41-7

Reaction Conditions

1.1 Reagents: Sulfuric acid ,  Ferrous sulfate ;  rt; 4 h, 120 °C
1.2 Reagents: Sodium hydroxide Solvents: Water ;  pH 13

Reference

Preparation of polycyclic TLR7/8 antagonists and use thereof in the treatment of immune disorders

, World Intellectual Property Organization, , ,

5-Bromo-8-chloroquinoline Raw materials

• Glycerol
• 5-Bromo-2-chloroaniline

5-Bromo-8-chloroquinoline Preparation Products

• 5-Bromo-8-chloroquinoline (927800-41-7)

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