Production Method 1

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium ,  Iodine Solvents: Tetrahydrofuran ;  heated; 10 °C; overnight, rt

Reference

Iron-Catalyzed Cross-Coupling of Thioesters and Organomanganese Reagents

Geiger, Valentin Jacob ; Lefevre, Guillaume; Fleischer, Ivana, Chemistry - A European Journal, 2022, 28(62),

Production Method 2

926-62-5

Reaction Conditions

Reference

Stereospecific Construction of Quaternary Carbon Stereocenters from Quaternary Carbon Stereocenters

Patel, Kaushalendra; Lanke, Veeranjaneyulu; Marek, Ilan, Journal of the American Chemical Society, 2022, 144(16), 7066-7071

Production Method 3

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran

Reference

Iridium-Catalyzed C(sp3)-H Borylation Using Silyl-Bipyridine Pincer Ligands

Kawazu, Ryohei; Torigoe, Takeru ; Kuninobu, Yoichiro, Angewandte Chemie, 2022, 61(22),

Production Method 4

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  40 - 45 °C; 2 h, 45 °C

Reference

Method for preparing 2-alkylthiazole compound with 2-(alkylthio)thiazole as starting material

, China, , ,

Production Method 5

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran

Reference

Silver-promoted cascade radical cyclization of γ,δ-unsaturated oxime esters with P(O)H compounds: synthesis of phosphorylated pyrrolines

Chen, Chen; Bao, Yinwei; Zhao, Jinghui; Zhu, Bolin, Chemical Communications (Cambridge, 2019, 55(97), 14697-14700

Production Method 6

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran

Reference

Pheromone synthesis. Part 261: Synthesis of four pyrazines produced by females of the Korean apricot wasp, Eurytoma maslovskii

Mori, Kenji; Yang, Chang Yeol, Tetrahedron, 2017, 73(32), 4766-4769

Production Method 7

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  1 h, 60 °C

Reference

Synthesis of ent-BE-43547A1 reveals a potent hypoxia-selective anticancer agent and uncovers the biosynthetic origin of the APD-CLD natural products

Villadsen, Nikolaj L.; Jacobsen, Kristian M. ; Keiding, Ulrik B.; Weibel, Esben T.; Christiansen, Bjoern; et al, Nature Chemistry, 2017, 9(3), 264-272

Production Method 8

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  40 min, rt; 1 h, rt; 20 h, rt

Reference

Practical large-scale production of dihydrocapsiate, a nonpungent capsaicinoid-like substance

Kurosawa, Wataru; Nakano, Takashi; Amino, Yusuke, Bioscience, 2017, 81(2), 211-221

Production Method 9

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium

Reference

Rhodium-Catalyzed Enantioselective Addition of Tricyclopropylboroxin to N-Sulfonylimines

Nishimura, Takahiro; Nagai, Tomotaka; Takechi, Ryosuke; Ebe, Yusuke, Synthesis, 2016, 48(16), 2612-2618

Production Method 10

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Diethyl ether ;  30 min, reflux; 4 h, reflux

Reference

Synthesis of 1,4-amino alcohols by Grignard reagent addition to THF and N-tosyliminobenzyliodinane

Tejo, Ciputra; See, Yang Feng Anders; Mathiew, Mitch; Chan, Philip Wai Hong, Organic & Biomolecular Chemistry, 2016, 14(3), 844-848

Production Method 11

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Diethyl ether ,  Water ;  0 °C; 30 min, rt; 15 min, reflux

Reference

Design, synthesis and antimalarial evaluation of novel thiazole derivatives

Bueno, Jose Maria; Carda, Miguel; Crespo, Benigno; Cunat, Ana Carmen; de Cozar, Cristina; et al, Bioorganic & Medicinal Chemistry Letters, 2016, 26(16), 3938-3944

Production Method 12

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  rt; 2 h, 50 °C

Reference

Enantioselective preparation of chromanone derivatives by metal-free catalytic hydrogenation

, China, , ,

Production Method 13

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Diethyl ether ;  0 °C; 0 °C → rt; 1 h, rt

Reference

One-step Asymmetric Construction of 1,4-Stereocenters via Tandem Mannich-Isomerization Reactions Mediated by a Dual-functional Betaine Catalyst

Deng, Yu; Shi, Xiaohuo; Shi, Guangfa; Lu, Xingyu; Luo, Jisheng ; et al, JACS Au, 2022, 2(12), 2678-2685

Production Method 14

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran ;  55 °C; 55 - 60 °C; 55 - 60 °C
1.2 Reagents: Zinc chloride Solvents: Tetrahydrofuran ;  -10 - -5 °C; 1 h, -10 - -5 °C

Reference

Preparation of alkylaniline compounds

, China, , ,

Production Method 15

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium ;  rt

Reference

Novel method for preparing repaglinide intermediate (3-methyl-1-(2-(piperidin-1-yl)phenyl)butan-1-amine) by subjecting o-fluorobenzonitrile to Grignard reaction, condensation reaction and reduction reaction

, China, , ,

Production Method 16

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran ;  1.5 h, 60 °C

Reference

One-Pot Synthesis of 4-Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Arene

Lee, Seok Beom; Jang, Yoonkyung; Ahn, Jiwon; Chun, Simin; Oh, Dong-Chan ; et al, Organic Letters, 2020, 22(21), 8382-8386

Production Method 17

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Diethyl ether

Reference

Synthesis and Biological Evaluation of 3-cyano-4H-chromene Derivatives Bearing Carbamate Functionality

Boukattaya, Fatma; Daoud, Amal; Boeda, Fabien; Pearson-Long, Morwenna S. M.; Gharsallah, Neji; et al, Medicinal Chemistry (Sharjah, 2019, 15(3), 257-264

Production Method 18

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  70 °C; 70 °C → rt; rt; 2 h, rt

Reference

Palladium-catalyzed intramolecular reductive olefin hydrocarbonation: benzylic hydrogen serving as a new hydrogen donor

Dong, Xu; Cui, Jie; Song, Jian; Han, Ying; Liu, Qing; et al, Chemical Communications (Cambridge, 2017, 53(36), 4903-4906

Production Method 19

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  0 °C

Reference

Syntheses and characterization of molecular weight enlarged olefin metathesis pre-catalysts

Keraani, Adel; Nasser, Ghassan; Shahane, Saurabh; Renouard, Thierry; Bruneau, Christian ; et al, Comptes Rendus Chimie, 2017, 20(7), 717-723

Production Method 20

926-62-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  rt; rt → reflux; 90 min, reflux

Reference

Total synthesis and biological evaluation of rakicidin A and discovery of a simplified bioactive analog

Tsakos, Michail; Clement, Lise L.; Schaffert, Eva S.; Olsen, Frank N.; Rupiani, Sebastiano; et al, Angewandte Chemie, 2016, 55(3), 1030-1035

Isobutylmagnesium Bromide Preparation Products

• Isobutylmagnesium Bromide (926-62-5)

• 1. An atmosphere and light tuned highly diastereoselective synthesis of cyclobuta/penta[b]indoles from aniline-tethered alkylidenecyclopropanes with alkynes?
  Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
• 2. Alumina coating on 5 V lithium cobalt fluorophosphate cathode material for lithium secondary batteries – synthesis and electrochemical properties?
  S. Amaresh,K. Karthikeyan,K. J. Kim,Y. S. Lee RSC Adv., 2014,4, 23107-23115
• 3. An approach to the structure and vibrational analysis of cis- and trans-3-chlorostyrene through IR/Raman and INS spectroscopies and theoretical ab initio/DFT calculations?
  J. M. Granadino-Roldán,M. Fernández-Gómez,A. Navarro,T. Pe?a Ruiz,U. A. Jayasooriya Phys. Chem. Chem. Phys., 2004,6, 1133-1143
• 4. An Aptamer Bio-barCode (ABC) assay using SPR, RNase H, and probes with RNA and gold-nanorods for anti-cancer drug screening
  Chengbin Yang,Hing Lun Tsang,Pui Man Lau,Ken-Tye Yong,Ho Pui Ho,Siu Kai Kong Analyst, 2017,142, 3579-3587
• 5. Acenaphthenic hopanoids, a novel series of aromatised
  Teresita Carrillo-Hernández,Philippe Schaeffer,Pierre Albrecht Chem. Commun., 2001, 1976-1977

• Solvents and Organic Chemicals Organic Compounds Organic salts Organic metal salts Organic metal halides
• Other Chemical Reagents Organic Metal Reagents

• 33974-41-3(Magnesium, bromo(2,2-dimethylpropyl)-)
• 927-77-5(Magnesium, bromopropyl-(7CI,8CI,9CI))
• 14627-81-7(Magnesium, bis(1,1-dimethylethyl)-)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)