Cas no 923119-59-9 (2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine)

2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine is a fluorinated and chlorinated pyrimidine derivative featuring a pyrrolidine substituent at the 4-position. This heterocyclic compound serves as a versatile intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of active ingredients requiring selective functionalization. The presence of both chloro and fluoro groups enhances its reactivity in nucleophilic substitution reactions, while the pyrrolidine moiety contributes to steric and electronic modulation. Its well-defined structure and high purity make it suitable for precision applications in medicinal chemistry, including the synthesis of kinase inhibitors and other biologically active molecules. The compound is typically handled under controlled conditions due to its sensitivity to moisture and light.
2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine structure
923119-59-9 structure
Product Name:2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine
CAS No:923119-59-9
MF:C8H9ClFN3
MW:201.628563642502
MDL:MFCD09063015
CID:1078896
Update Time:2025-10-23

2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine Chemical and Physical Properties

Names and Identifiers

    • 2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine
    • 2-CHLORO-5-FLUORO-4-(1-PYRROLIDINYL)PYRIMIDINE
    • 2-Chloro-5-fluoro-4-pyrrolidin-1-ylpyrimidine
    • MDL: MFCD09063015
    • Inchi: 1S/C8H9ClFN3/c9-8-11-5-6(10)7(12-8)13-3-1-2-4-13/h5H,1-4H2
    • InChI Key: BDJGBPUMVHZREY-UHFFFAOYSA-N
    • SMILES: ClC1=NC=C(C(=N1)N1CCCC1)F

Computed Properties

  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1

2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine Security Information

  • Hazard Category Code: 36
  • Safety Instruction: 26

2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine Pricemore >>

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