- Enzymatic synthesis of D-cysteine by 3-chloro-D-alanine resistant Pseudomonas putida CR 1-1Nagasawa, Toru; Yamano, Hironori; Ohkishi, Haruyuki; Hosono, Hidekazu; Tani, Yoshiki; et al, Agricultural and Biological Chemistry, 1982, 46(12), 3003-10
Cas no 921-01-7 (D-Cysteine)
D-Cysteine structure
Product Name:D-Cysteine
CAS No:921-01-7
MF:C3H7NO2S
MW:121.158179521561
MDL:MFCD00066461
CID:40224
PubChem ID:57648407
Update Time:2025-09-26
D-Cysteine Chemical and Physical Properties
Names and Identifiers
-
- D-Cysteine
- D-CYS-OH
- H-D-CYS-OH
- RARECHEM AB PP 1441
- (S)-2-AMINO-3-MERCAPTOPROPIONIC ACID
- D-cysteine free base crystalline
- D-Cysteinefreebase
- (2S)-2-amino-3-sulfanyl-propanoic acid
- D-Cysteine (9CI)
- H-D-Cys-OH (D-Cysteine)
- (S)-2-Amino-3-mercaptopropanoic acid
- (2S)-2-amino-3-sulfanylpropanoic acid
- (D,L)-H-Cys-OH
- 2-amino-3-sulfopropionic acid
- Cysteine,D
- D-Amino-3-mercaptopropionic acid
- D-Cystein
- D-Zystein
- Cysteine, D-
- D-Cys
- cysteine
- D-cysteinyl radical
- (2S)-2-amino-3-mercaptopropanoic acid
- IU8WN3PPI2
- DCY
- C3H7NO2S
- (S)-Cysteine
- Epitope ID:140790
- D-Amino-3-mercaptopropionate
- GTPL4537
- Cysteine, D- (8CI)
- D
- 18: PN: CN107114752 PAGE: 2 claimed sequence
- 1f57
- CYSTEINE. (S)-
- Q16633812
- C00793
- 921-01-7
- SCHEMBL95110
- 4A30FFBA-E85B-4310-BCD5-5414B37D35D0
- CHEBI:16375
- NS00079857
- CCRIS 5542
- CHEMBL171281
- AM81647
- UNII-IU8WN3PPI2
- CS-W019341
- MFCD00066461
- NCGC00163332-01
- DTXSID60893798
- XUJNEKJLAYXESH-UWTATZPHSA-N
- Q27115094
- C-9600
- BP-20435B
- D-Cysteine, >=99% (RT)
- (S)-2-amino-3-mercaptopropanoicacid
- BDBM50109584
- HY-W018555
- EINECS 213-062-0
- DB03201
- AS-12790
- AKOS006239329
- EN300-122633
- C
- E 920
- cisteina
- 2-amino-3-sulfanylpropanoic acid
- E-920
- L-Zystein
- L-2-Amino-3-mercaptopropionic acid
- L-(+)-Cysteine hydrochloride
- Cysteine hydrochloride (anhydrous)
- Cysteine HCl (anhydrous)
- L-Cysteine
- (R)-2-amino-3-mercaptopropanoic acid
- Hcys
- L-Cys
- Cys
- 2-Amino-3-mercaptopropionic acid
- L-Cystein
- L-cysteinium chloride
- FREE CYSTEINE
- E920
- L-Cysteine monohydrochloride
- Cystein
- 2-amino-3-mercaptopropanoic acid
- (2R)-2-amino-3-mercaptopropanoic acid
- (2R)-2-amino-3-sulfanylpropanoic acid
- Cysteine monohydrochloride
- Zystein
- (R)-Cysteine hydrochloride
-
- MDL: MFCD00066461
- Inchi: 1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m1/s1
- InChI Key: XUJNEKJLAYXESH-UWTATZPHSA-N
- SMILES: [C@@H](N)(CS)C(=O)O
- BRN: 1721407
Computed Properties
- Exact Mass: 121.02000
- Monoisotopic Mass: 121.02
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 7
- Rotatable Bond Count: 2
- Complexity: 75.3
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: -2.5
- Topological Polar Surface Area: 64.3
Experimental Properties
- Color/Form: Not available
- Density: 1.334
- Melting Point: ~230?°C (dec.)
- Boiling Point: 293.9 °C at 760 mmHg
- Flash Point: 131.5 °C
- Refractive Index: 1.549
- Water Partition Coefficient: Soluble in water (partly).
- Stability/Shelf Life: Stable. Incompatible with strong oxidizing agents.
- PSA: 102.12000
- LogP: 0.02840
- Sensitiveness: Air Sensitive
- Specific Rotation: -7.6 ±1.0° (c=5,in 5M HCl)
- Optical Activity: [α]20/D ?7.6±1.0°, c =?5% in 5 M HCl
- Solubility: Not available
D-Cysteine Security Information
-
Symbol:
- Signal Word:Warning
- Hazard Statement: H302
- Warning Statement: P264; P270; P301+P312; P330; P501
- Hazardous Material transportation number:NONH for all modes of transport
- WGK Germany:3
- Hazard Category Code: 22
- Safety Instruction: S26; S36/37/39
- FLUKA BRAND F CODES:10-23
-
Hazardous Material Identification:
- Storage Condition:Store at room temperature
- Risk Phrases:R36/37/38
D-Cysteine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| MedChemExpress | HY-W018555-25mg |
D-Cysteine |
921-01-7 | ≥97.0% | 25mg |
¥600 | 2022-05-18 | |
| Fluorochem | 049424-5g |
D-Cysteine |
921-01-7 | 95% | 5g |
£24.00 | 2022-03-01 | |
| Fluorochem | 049424-25g |
D-Cysteine |
921-01-7 | 95% | 25g |
£80.00 | 2022-03-01 | |
| Fluorochem | 049424-100g |
D-Cysteine |
921-01-7 | 95% | 100g |
£240.00 | 2022-03-01 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BC6238-100g |
D-Cysteine |
921-01-7 | ≥98% | 100g |
¥1650元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BC6238-25g |
D-Cysteine |
921-01-7 | ≥98% | 25g |
¥590元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BC6238-5g |
D-Cysteine |
921-01-7 | ≥98% | 5g |
¥180元 | 2023-09-15 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | T10933-5 mg |
D-Cysteine |
921-01-7 | 97.00% | 5mg |
¥287.00 | 2022-04-26 | |
| abcr | AB282939-5 g |
(S)-2-Amino-3-mercaptopropionic acid, 95% (H-D-Cys-OH); . |
921-01-7 | 95% | 5 g |
€82.00 | 2023-07-20 | |
| abcr | AB282939-10 g |
(S)-2-Amino-3-mercaptopropionic acid, 95% (H-D-Cys-OH); . |
921-01-7 | 95% | 10 g |
€91.30 | 2023-07-20 |
D-Cysteine Production Method
Production Method 1
Reaction Conditions
Reference
Production Method 2
Reaction Conditions
Reference
- Synthesis of D-cysteine from a racemate of 3-chloroalanine by phenylhydrazine-treated cells of Pseudomonas putida CR 1-1Nagasawa, Toru; Hosono, Hidekazu; Yamano, Hironori; Ohkishi, Haruyuki; Tani, Yoshiki; et al, Agricultural and Biological Chemistry, 1983, 47(4), 861-8
Production Method 3
Reaction Conditions
1.1 Reagents: Water ; 1.5 h, rt → reflux
1.2 Reagents: Triethylamine ; pH 5
1.3 Reagents: Ethanol ; 10 min
1.2 Reagents: Triethylamine ; pH 5
1.3 Reagents: Ethanol ; 10 min
Reference
- New process for preparation of D-cysteine from L-cysteine by asymmetricYu, Mingjun; Jiang, Lijian; Wu, Liuyang; Li, Jianjun, Yingyong Huagong, 2007, 36(5), 488-490
Production Method 4
Production Method 5
Production Method 6
Reaction Conditions
1.1 Reagents: Water ; 1.5 h, reflux
1.2 Reagents: Ammonia Solvents: Water ; pH 3
1.2 Reagents: Ammonia Solvents: Water ; pH 3
Reference
- Method for preparing D-cysteine hydrochloride monohydrate having high optical purity, China, , ,
Production Method 7
Production Method 8
Production Method 9
Reaction Conditions
1.1 Solvents: Water ; 1.5 h, 80 °C
1.2 Reagents: Triethylamine ; pH 5
1.2 Reagents: Triethylamine ; pH 5
Reference
- Study of the process for preparation of D-homocysteine from L-homocysteine hydrochlorideZhao, Min-juan; Li, Ning-ning; Lu, Jiu-fu, Zhejiang Huagong, 2012, 43(11), 18-21
Production Method 10
Reaction Conditions
1.1 Reagents: Hydroxyamine hydrochloride
Reference
- Optical resolution by preferential crystallization of DL-thiazolidine-4-carboxylic acidShiraiwa, Tadashi; Sado, Yujin; Komure, Masamitsu; Kurokawa, Hidemoto, Chemistry Letters, 1987, (4), 621-2
Production Method 11
Reaction Conditions
1.1 Reagents: Hydrochloric acid Solvents: Water ; rt → 100 °C
1.2 Reagents: L-Dibenzoyltartaric acid ; 30 min, 80 - 100 °C; 1 h, 60 °C; 60 °C → 15 °C
1.3 Reagents: Triethylamine Solvents: Ethanol ; 1 h, 15 °C
1.2 Reagents: L-Dibenzoyltartaric acid ; 30 min, 80 - 100 °C; 1 h, 60 °C; 60 °C → 15 °C
1.3 Reagents: Triethylamine Solvents: Ethanol ; 1 h, 15 °C
Reference
- Chemical resolution of L-cysteine and D-cysteine, China, , ,
Production Method 12
Reaction Conditions
1.1 Reagents: Acetic acid , Propionic acid Solvents: Acetone ; 0.5 h, 80 °C
1.2 10 h, 80 °C
1.3 Reagents: L-Phenylalanine ; 0.2 h, 80 °C
1.4 Reagents: Water ; 2 h, heated
1.5 Reagents: Sodium hydroxide Solvents: Water ; pH 4.9
1.2 10 h, 80 °C
1.3 Reagents: L-Phenylalanine ; 0.2 h, 80 °C
1.4 Reagents: Water ; 2 h, heated
1.5 Reagents: Sodium hydroxide Solvents: Water ; pH 4.9
Reference
- A simple method for producing D-cysteine with L-cysteine as raw material, China, , ,
Production Method 13
Reaction Conditions
1.1 Reagents: Water ; 3 h, 1 atm, 60 °C
1.2 Reagents: Ammonia Solvents: Water ; pH 3.5
1.2 Reagents: Ammonia Solvents: Water ; pH 3.5
Reference
- Process for preparation of D-cystine, China, , ,
Production Method 14
Reaction Conditions
1.1 Solvents: Water ; 1.5 h, reflux
1.2 Reagents: Triethylamine ; pH 3.6
1.2 Reagents: Triethylamine ; pH 3.6
Reference
- Process for preparation of D-cysteine hydrochloride monohydrate, China, , ,
Production Method 15
Reaction Conditions
1.1 Reagents: Sodium hydroxide , Phosphoric acid Solvents: Water ; rt; pH 7.2, rt → 40 °C; 44 h, pH 7.2
Reference
- Process for the enzymic preparation of enantiomerically enriched D-amino acids, World Intellectual Property Organization, , ,
Production Method 16
Reaction Conditions
Reference
- Asymmetric transformation of (RS)-cysteine via formation of (RS)-4-thiazolidinecarboxylic acidsShiraiwa, Tadashi; Kataoka, Kazuo; Sakata, Shinji; Kurokawa, Hidemoto, Bulletin of the Chemical Society of Japan, 1989, 62(1), 109-13
Production Method 17
Production Method 18
Production Method 19
D-Cysteine Raw materials
- (S)-2-Amino-3-chloropropanoic acid
- (4R)-2,2-Dimethyl-4-thiazolidinecarboxylic acid
- L(+)-Tartaric acid
- (4S)-2,2-dimethyl-1,3-thiazolidine-4-carboxylic acid
- 2-Amino-3-mercaptopropanoic acid
- L-Thioproline
- β-Chloro-L-alanine
- D-Cysteine
- D-Cystine
- L-Cysteine
- D-Thiaproline
- N-Carbamoyl-L-cysteine
- 3-chloroalanine
D-Cysteine Preparation Products
D-Cysteine Suppliers
Amadis Chemical Company Limited
Gold Member
(CAS:921-01-7)D-Cysteine
Order Number:A844146
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 07:02
Price ($):400.0
Email:[email protected]
Suzhou Senfeida Chemical Co., Ltd
Gold Member
(CAS:921-01-7)D-Cysteine
Order Number:sfd10086
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Email:[email protected]
D-Cysteine Related Literature
-
Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068
-
Huiying Xu,Lu Zheng,Yu Zhou,Bang-Ce Ye Analyst, 2021,146, 5542-5549
-
Chandran Rajendran,Govindaswamy Satishkumar,Charlotte Lang,Eric M. Gaigneaux Catal. Sci. Technol., 2020,10, 2583-2592
-
Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
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