Production Method 1

57190-17-7

92035-95-5

Reaction Conditions

1.1 Reagents: Butyllithium Solvents: Hexane ;  -23 °C → -29 °C; -29 °C → 0 °C; 1 h, 0 °C
1.2 0 °C

Reference

Preparation of phosphonamides as ACAT inhibitors

, United States, , ,

Production Method 2

57190-17-7

92035-95-5

Reaction Conditions

1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran ,  Hexane ;  -78 °C; 1 h, -78 °C
1.2 rt
1.3 Reagents: Hydrochloric acid Solvents: Water ;  pH 2 - 3, rt

Reference

Milled Dry Ice as a C1 Source for the Carboxylation of Aryl Halides

O'Brien, Connor J.; Nicewicz, David A., Synlett, 2021, 32(8), 814-816

Production Method 3

501085-08-1

92035-95-5

Reaction Conditions

1.1 Reagents: Methyl iodide ;  15 h, rt
1.2 Reagents: Sodium hydroxide Solvents: Methanol ;  15 h, reflux

Reference

N-Aroyl-l-Phenylalanine Derivatives as VCAM/VLA-4 Antagonists

Sidduri, Achyutharao; Tilley, Jefferson W.; Lou, Jian Ping; Chen, Li; Kaplan, Gerry; et al, Bioorganic & Medicinal Chemistry Letters, 2002, 12(17), 2479-2482

Production Method 4

92035-95-5

Reaction Conditions

Reference

Application of 2,6-diisopropyl-benzoic acid and its derivatives to neuroprotective agent

, China, , ,

Production Method 5

163704-47-0

92035-95-5

Reaction Conditions

1.1 Reagents: Butyllithium
1.2 -

Reference

New building blocks for the assembly of sequence selective molecular zippers

Hunter, Chistopher A.; Jones, Philip S.; Tiger, Pascale M. N.; Tomas, Salvador, Chemical Communications (Cambridge, 2003, (14), 1642-1643

Production Method 6

57190-17-7

92035-95-5

Reaction Conditions

1.1 Reagents: Butyllithium Solvents: Diethyl ether ,  Hexane ;  -78 °C; -78 °C → rt; 1 h, rt; rt → 0 °C
1.2 0 °C; 30 min, rt

Reference

Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and application to total synthesis of (-)-morphine

Zhang, Qing; Zhang, Fu-Min; Zhang, Chang-Sheng; Liu, Si-Zhan; Tian, Jin-Miao; et al, Nature Communications, 2019, 10(1), 1-7

Production Method 7

57190-17-7

92035-95-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  rt; 4 h, reflux; reflux → 0 °C
1.2 3 h, rt
1.3 Reagents: Hydrochloric acid Solvents: Water

Reference

Electrolytic solutions for aluminum electrolytic capacitors, and aluminum electrolytic capacitors using them

, Japan, , ,

Production Method 8

2078-54-8

92035-95-5

Reaction Conditions

1.1 Reagents: Trifluoromethanesulfonic anhydride Catalysts: 4-(Dimethylamino)pyridine Solvents: Dichloromethane ;  30 min, -70 °C; -70 °C → rt; 3 h, rt
1.2 Reagents: Triethylamine Catalysts: Palladium diacetate ,  1,3-Bis(diphenylphosphino)propane Solvents: Acetonitrile ,  Water ;  5 min, 40 psi, 83 - 85 °C; 3 h, 83 - 85 °C; 85 °C → rt
1.3 Reagents: Sodium hydroxide Solvents: Water ;  neutralized

Reference

Preparation of N-alkanoylphenylalanine derivatives as vascular cell adhesion molecule-1 (VCAM-1) binding inhibitors

, World Intellectual Property Organization, , ,

Production Method 9

92035-95-5

Reaction Conditions

Reference

Carboxamide and urea derivatives having ACAT-inhibiting activity

, European Patent Organization, , ,

Production Method 10

101-81-5

92035-95-5

66415-27-8

49623-71-4

253584-86-0

Reaction Conditions

1.1 Reagents: 1,1′-[1,2-Phenylenebis(methylene)]bis[1,1-diphenylphosphine] Catalysts: Palladium diacetate Solvents: Methanol ;  rt → 150 °C
1.2 60 atm, 150 °C; 150 °C → rt

Reference

Catalyst composition for preparing 3-pentenoic ester from butadiene

, United States, , ,

2,6-Diisopropylbenzoic Acid Raw materials

• Oxazole, 2-[2,6-bis(1-methylethyl)phenyl]-4,5-dihydro-4,4-dimethyl-
• 2,6-Diisopropyliodobenzene
• Propofol
• 2-Bromo-1,3-diisopropylbenzene
• benzylbenzene

2,6-Diisopropylbenzoic Acid Preparation Products

• Benzoic acid, 2,4,6-tris(1,1-dimethylethyl)- (66415-27-8)
• 2,4,6-Triisopropylbenzoic acid (49623-71-4)
• 2,6-Diisopropylbenzoic Acid (92035-95-5)
• 2,6-Di-tert-butylbenzoic acid (253584-86-0)

• 1. Excess electrons in lithium–ethylamine solutions—density, electrical conductivity and EPR studies
  Phys. Chem. Chem. Phys., 1999,1, 3561-3565
• 2. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 3. Evolution and characterization of a benzylguanine-binding RNA aptamer?
  J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
• 4. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538
• 5. Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides?
  Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Cumenes

• 2438-04-2(2-Isopropylbenzoic acid)
• 1077-58-3(2-tert-butylbenzoic acid)
• 49623-71-4(2,4,6-Triisopropylbenzoic acid)
• 3158-74-5(2-Cyclopropylbenzoic acid)
• 612-19-1(2-Ethylbenzoic acid)
• 612-35-1(2-Benzylbenzoic acid)
• 108961-55-3(2,4-Bis(propan-2-yl)benzoic Acid)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)