Cas no 919789-77-8 (DHTPE)

DHTPE structure
DHTPE structure
Product Name:DHTPE
CAS No:919789-77-8
MF:C26H20O2
MW:364.435807228088
CID:761012
Update Time:2024-10-26

DHTPE Chemical and Physical Properties

Names and Identifiers

    • Phenol, 4,4'-(2,2-diphenylethenylidene)bis-
    • 4-[1-(4-hydroxyphenyl)-2,2-diphenylethenyl]phenol
    • 4,4'-(2,2-Diphenylethenylidene)bisphenol
    • 4,4'-(2,2-Diphenylethene-1,1-diyl)diphenol
    • 4,4′-(2,2-Diphenylethenylidene)bis[phenol] (ACI)
    • 1,1-Bis(4-hydroxyphenyl)-2,2-diphenylethene
    • 1,1-Diphenyl-2,2-bis(4-hydroxyphenyl)ethylene
    • 4,4′-(2,2-Diphenylethenylidene)diphenol
    • DHTPE
    • Inchi: 1S/C26H20O2/c27-23-15-11-21(12-16-23)26(22-13-17-24(28)18-14-22)25(19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-18,27-28H
    • InChI Key: OXBSSBYVVMIMMP-UHFFFAOYSA-N
    • SMILES: OC1C=CC(/C(=C(\C2C=CC=CC=2)/C2C=CC=CC=2)/C2C=CC(O)=CC=2)=CC=1

Computed Properties

  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 28
  • Rotatable Bond Count: 4
  • Complexity: 453
  • Topological Polar Surface Area: 40.5

DHTPE Pricemore >>

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4,4'-(2,2-Diphenylethene-1,1-diyl)diphenol
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DHTPE Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran
Reference
Multi-stimuli responsive fluorescence of amphiphilic AIEgen copolymers for ultrafast, highly sensitive and selective copper ion detection in water
Nhien, Pham Quoc ; Wu, Po-Hsun; Wu, Chia-Hua; Wu, Judy I.; Hue, Bui Thi Buu; et al, Sensors and Actuators, 2021, 344,

Production Method 2

Reaction Conditions
1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  0 °C; 24 h, 0 °C → rt
1.2 Reagents: Water
Reference
Proton conducting hybrid membrane electrolytes of sulfonated poly(ether sulfone)s and poly(ether sulfone)s containing metallophthalocyanine
Lim, Youngdon; Lee, Soonho; Seo, Dongwan; Jang, Hohyoun; Hossain, Awlad Md; et al, International Journal of Hydrogen Energy, 2014, 39(3), 1539-1548

Production Method 3

Reaction Conditions
1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  1 h, -45 °C; 6 h, rt
Reference
Thiophenol detection using an AIE fluorescent probe through self-assembly with TPE-based glycoclusters
Dong, Lei; Chen, Guo-Rong; He, Xiao-Peng; Vidal, Sebastien, Organic & Biomolecular Chemistry, 2019, 17(41), 9251-9256

Production Method 4

Reaction Conditions
1.1 Catalysts: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  -78 °C; 30 min, -78 °C; 8 h, -78 °C → rt; 15 h, 70 °C; cooled
1.2 Reagents: Potassium carbonate Solvents: Water
Reference
Electrochromic/electrofluorochromic poly(urea-urethane) bearing oligoaniline and tetraphenylethylene groups: Synthesis, characterization, and H2O2 visualized determination
Zhang, Yingchao; Xie, Yunfei; Zhou, Mingjuan; Berda, Erik B.; Chao, Danming, Dyes and Pigments, 2021, 194,

Production Method 5

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  rt → -5 °C; 10 °C; 10 °C → rt; 0.5 h, rt; 2.5 h, reflux; reflux → -5 °C
1.2 Reagents: Piperidine ;  10 min, -5 - 0 °C
1.3 Solvents: Tetrahydrofuran ;  -5 - 0 °C; -5 °C → reflux; 20 - 30 h, reflux
1.4 Reagents: Potassium carbonate Solvents: Water
Reference
A facile synthesis of tetraarylethenes via cross McMurry coupling between diaryl ketones
Duan, Xin-Fang; Zeng, Jing; Lu, Jia-Wei; Zhang, Zhan-Bin, Synthesis, 2007, (5), 713-718

Production Method 6

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  0 °C; 2 h, 0 °C → reflux
1.2 Solvents: Tetrahydrofuran ;  reflux; overnight, reflux
1.3 Reagents: Sodium bicarbonate Solvents: Water ;  pH 7
Reference
Cationic fluorescent probe based on tetraphenyl ethylene structure
, China, , ,

Production Method 7

Reaction Conditions
1.1 Reagents: Zinc Catalysts: Titanium tetrachloride Solvents: Tetrahydrofuran ;  cooled; rt; overnight, reflux
1.2 Reagents: Potassium carbonate Solvents: Water ;  30 min, reflux
Reference
Porous Organic Polymer from Aggregation-Induced Emission Macrocycle for White-Light Emission
Wang, Zhen; Yan, Sen; Cui, Huang-Chen; Cheng, Guang; Ma, Hui; et al, Macromolecules (Washington, 2018, 51(19), 7863-7871

Production Method 8

Reaction Conditions
1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  1 h, 0 °C; overnight, rt
1.2 Reagents: Sodium bicarbonate Solvents: Water ;  cooled
Reference
Bimodal Fluorescence-Magnetic Resonance Contrast Agent for Apoptosis Imaging
Li, Hao; Parigi, Giacomo ; Luchinat, Claudio; Meade, Thomas J., Journal of the American Chemical Society, 2019, 141(15), 6224-6233

Production Method 9

Reaction Conditions
1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  -78 °C; 1 h, -78 °C; -78 °C → rt; 12 h, rt
1.2 Reagents: Water ;  cooled
Reference
Process for preparation of zwitterion-modified tetraphenylethylene and application as cathode interfacial modification material bulk-heterojunction polymer solar cell
, China, , ,

Production Method 10

Reaction Conditions
1.1 Reagents: Boron tribromide Solvents: Dichloromethane ;  -78 °C; -78 °C → rt; 16 h, rt
1.2 Reagents: Water
Reference
Self-Assembly of Tetraphenylethene-Based [2]Catenane Driven by Acid-Base-Controllable Molecular Switching and Its Enabled Aggregation-Induced Emission
Ramakrishnam Raju, Mandapati V.; Lin, Hong-Cheu, Organic Letters, 2014, 16(21), 5564-5567

Production Method 11

Reaction Conditions
1.1 Reagents: p-Toluenesulfonic acid Solvents: Toluene ;  2.5 h, reflux
Reference
Method for identifying and resolving chiral compounds using AIE molecules
, China, , ,

Production Method 12

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  cooled; overnight, 70 °C; 70 °C → rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  rt
Reference
Multi-Stimuli Responsive FRET Processes of Bifluorophoric AIEgens in an Amphiphilic Copolymer and Its Application to Cyanide Detection in Aqueous Media
Nhien, Pham Quoc; Chou, Wei-Lun; Cuc, Tu Thi Kim; Khang, Trang Manh; Wu, Chia-Hua; et al, ACS Applied Materials & Interfaces, 2020, 12(9), 10959-10972

Production Method 13

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  0 °C; 2 h, reflux
1.2 Solvents: Tetrahydrofuran ;  3 h, reflux
Reference
Design and synthesis of Norendoxifen analogues with dual aromatase inhibitory and estrogen receptor modulatory activities
Lv, Wei; Liu, Jinzhong; Skaar, Todd C.; Flockhart, David A.; Cushman, Mark, Journal of Medicinal Chemistry, 2015, 58(6), 2623-2648

Production Method 14

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  -10 °C; -10 °C → rt; 2 h, 90 °C; cooled
1.2 Solvents: Tetrahydrofuran ;  3 h, 90 °C
1.3 Reagents: Potassium carbonate Solvents: Water ;  0 °C
Reference
Novel ridaifen analog, method for producing same, and antitumor agent
, World Intellectual Property Organization, , ,

Production Method 15

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  0 °C; 6 h, rt → reflux
1.2 Reagents: Hydrochloric acid Solvents: Water
Reference
Redox-Active AIEgen-Derived Plasmonic and Fluorescent Core@Shell Nanoparticles for Multimodality Bioimaging
He, Xuewen ; Zhao, Zheng; Xiong, Ling-Hong; Gao, Peng Fei; Peng, Chen; et al, Journal of the American Chemical Society, 2018, 140(22), 6904-6911

Production Method 16

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  0 °C; 0.5 h, rt; 5 h, reflux
1.2 Reagents: Water
Reference
Aggregation-Induced Emission Materials with Narrowed Emission Band by Light-Harvesting Strategy: Fluorescence and Chemiluminescence Imaging
Zhu, Xin; Wang, Jian-Xin; Niu, Li-Ya ; Yang, Qing-Zheng, Chemistry of Materials, 2019, 31(9), 3573-3581

Production Method 17

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  -10 °C; -10 °C → rt; 0.5 h, rt; rt → 75 °C; 12 h, 75 °C
Reference
Preparation and application of sodium tetrastyryl disulfonate
, China, , ,

Production Method 18

Reaction Conditions
1.1 Reagents: Zinc ,  Titanium tetrachloride Solvents: Tetrahydrofuran ;  10 min, rt; overnight, reflux
Reference
Phenol-yne Click Polymerization: An Efficient Technique to Facilely Access Regio- and Stereoregular Poly(vinylene ether ketone)s
Shi, Yang; Bai, Tianwen; Bai, Wei; Wang, Zhe; Chen, Ming; et al, Chemistry - A European Journal, 2017, 23(45), 10725-10731

Production Method 19

Reaction Conditions
1.1 Reagents: Butyllithium Catalysts: p-Toluenesulfonic acid Solvents: Tetrahydrofuran ;  6 h, rt
Reference
Transparent thermoplastic copolymer with excellent heat resistance and impact strength and its manufacturing method
, Korea, , ,

Production Method 20

Reaction Conditions
1.1 Reagents: Boron tribromide Solvents: Dichloromethane ,  Water ;  24 h, rt
Reference
Sulfonated poly(ether sulfone) polymer electrolyte membrane containing metallophthalocyanine and method for manufacturing the same
, Korea, , ,

DHTPE Raw materials

DHTPE Preparation Products

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