Production Method 1

91902-58-8

Reaction Conditions

1.1 Reagents: Chlorosulfonic acid Solvents: Chloroform ;  1 - 2 min, 0 °C

Reference

Regioselective synthesis of alkylarenes by two-step ipso-substitution of aromatic dicarboxylic acids

Bramborg, Andrea; Linker, Torsten, European Journal of Organic Chemistry, 2012, 2012(28), 5552-5563

Production Method 2

73765-07-8

91902-58-8

Reaction Conditions

1.1 Reagents: Carbon dioxide ,  Magnesium

Reference

Stereochemistry of metal ammonia ring reduction of aryl carboxylates and ketones and NMR conformational analysis of the dihydro aromatic products

Rabideau, Peter W.; Day, Lisa M.; Husted, Cynthia A.; Mooney, Jennifer L.; Wetzel, Donna M., Journal of Organic Chemistry, 1986, 51(10), 1681-6

Production Method 3

824430-38-8

91902-58-8

Reaction Conditions

1.1 Reagents: Potassium hydroxide Solvents: Diethylene glycol ;  8 h, reflux
1.2 Reagents: Hydrochloric acid Solvents: Water ;  acidified, rt

Reference

Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists

Huffman, John W.; Zengin, Gulay; Wu, Ming-Jung; Lu, Jianzhong; Hynd, George; et al, Bioorganic & Medicinal Chemistry, 2004, 13(1), 89-112

4-Ethyl-1-naphthoic acid Raw materials

• 4-Ethyl-N,N-diphenyl-1-naphthalenecarboxamide
• 1-(1-Bromoethyl)naphthalene

4-Ethyl-1-naphthoic acid Preparation Products

• 4-Ethyl-1-naphthoic acid (91902-58-8)

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• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes Naphthalenecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes Naphthalenecarboxylic acids and derivatives Naphthalenecarboxylic acids

• 55720-22-4(1,2-Dihydroacenaphthylene-5-carboxylic acid)
• 6639-25-4(Benzoic acid,3-(1-naphthalenylcarbonyl)-)
• 5698-99-7(1,2-dihydroacenaphthylene-5,6-dicarboxylic acid)
• 819077-62-8(1-Naphthalenecarboxylic acid, 4-[(4-carboxyphenyl)methyl]-)
• 918531-41-6(4-Pyrenecarboxylic acid, 2,7-bis(1,1-dimethylethyl)-)
• 614754-39-1(6-(2-Hydroxyethyl)-1-naphthoic Acid)
• 88475-91-6(Benzoic acid, 4-(1-pyrenylcarbonyl)-)
• 824430-41-3(1-Naphthalenecarboxylicacid, 7-ethyl-)
• 107777-22-0(4-Propyl-1-naphthoic acid)
• 496926-71-7(1-Azulenecarboxylic acid, 3-ethyl-)