Cas no 916420-24-1 (2-Isopropyl-4-trifluoromethylthiazole)

2-Isopropyl-4-trifluoromethylthiazole is a fluorinated thiazole derivative characterized by its unique structural properties, including an isopropyl substituent at the 2-position and a trifluoromethyl group at the 4-position. This compound is of interest in agrochemical and pharmaceutical research due to its potential as a building block for active ingredients. The trifluoromethyl group enhances lipophilicity and metabolic stability, while the thiazole core contributes to its heterocyclic reactivity. Its well-defined synthesis route allows for consistent purity and scalability. Applications may include use as an intermediate in the development of crop protection agents or bioactive molecules, leveraging its structural versatility and fluorine-based electronic effects.
2-Isopropyl-4-trifluoromethylthiazole structure
916420-24-1 structure
Product Name:2-Isopropyl-4-trifluoromethylthiazole
CAS No:916420-24-1
MF:C7H8F3NS
MW:195.205330848694
CID:1075789
PubChem ID:16427112
Update Time:2025-05-22

2-Isopropyl-4-trifluoromethylthiazole Chemical and Physical Properties

Names and Identifiers

    • 2-Isopropyl-4-trifluoromethylthiazole
    • 2-(1-methylethyl)-4-(trifluoromethyl)Thiazole
    • PRLMUSHZOWBWAM-UHFFFAOYSA-N
    • 916420-24-1
    • 2-(Propan-2-yl)-4-(trifluoromethyl)-1,3-thiazole
    • CS-0365382
    • AKOS006343973
    • 2-propan-2-yl-4-(trifluoromethyl)-1,3-thiazole
    • 2-Isopropyl-4-(trifluoromethyl)-1,3-thiazole
    • 2-Isopropyl-4-(trifluoromethyl)thiazole
    • FT-0685344
    • SCHEMBL9908284
    • DTXSID50586026
    • J-509749
    • DB-079113
    • MDL: I188242
    • Inchi: 1S/C7H8F3NS/c1-4(2)6-11-5(3-12-6)7(8,9)10/h3-4H,1-2H3
    • InChI Key: PRLMUSHZOWBWAM-UHFFFAOYSA-N
    • SMILES: S1C=C(C(F)(F)F)N=C1C(C)C

Computed Properties

  • Exact Mass: 195.03295492g/mol
  • Monoisotopic Mass: 195.03295492g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 157
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3
  • Topological Polar Surface Area: 41.1?2

2-Isopropyl-4-trifluoromethylthiazole Security Information

  • Hazard Statement: Irritant
  • Hazardous Material Identification: Xi

2-Isopropyl-4-trifluoromethylthiazole Pricemore >>

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Additional information on 2-Isopropyl-4-trifluoromethylthiazole

2-Isopropyl-4-trifluoromethylthiazole: A Comprehensive Overview

2-Isopropyl-4-trifluoromethylthiazole (CAS No. 916420-24-1) is a heterocyclic compound with a unique structure that has garnered significant attention in various fields of chemistry and materials science. This compound belongs to the thiazole family, which is a five-membered aromatic ring containing sulfur and nitrogen atoms. The presence of the isopropyl group and the trifluoromethyl group in its structure contributes to its distinct chemical properties, making it a valuable molecule for research and industrial applications.

The synthesis of 2-isopropyl-4-trifluoromethylthiazole involves a combination of nucleophilic substitution and cyclization reactions. Recent advancements in synthetic chemistry have enabled the efficient production of this compound with high purity, ensuring its suitability for both academic and commercial purposes. The molecule's structure is characterized by the isopropyl group at the 2-position and the trifluoromethyl group at the 4-position, which are key features influencing its reactivity and stability.

One of the most notable applications of 2-isopropyl-4-trifluoromethylthiazole is in the field of materials science, particularly in the development of advanced polymers and composites. The compound's ability to act as a building block for more complex structures has been extensively studied in recent years. For instance, researchers have explored its use in creating high-performance thermoplastics with enhanced mechanical properties. These materials are finding applications in aerospace, automotive industries, and electronics due to their lightweight nature and resistance to environmental factors.

In addition to its role in polymer synthesis, 2-isopropyl-4-trifluoromethylthiazole has also been investigated for its potential in pharmaceuticals. The compound's unique electronic properties make it a promising candidate for drug design, particularly in targeting specific biological pathways. Recent studies have highlighted its ability to inhibit certain enzymes associated with neurodegenerative diseases, suggesting its potential as a lead compound for developing new therapeutic agents.

The environmental impact of 2-isopropyl-4-trifluoromethylthiazole has also been a topic of interest among scientists. Given its widespread use in industrial applications, understanding its degradation pathways and ecological effects is crucial. Research indicates that the compound undergoes biodegradation under specific conditions, reducing its persistence in the environment. However, further studies are required to fully assess its long-term effects on ecosystems.

From a toxicological perspective, 2-isopropyl-4-trifluoromethylthiazole exhibits low acute toxicity in experimental models, which is reassuring for its safe handling in industrial settings. Nonetheless, long-term exposure studies are essential to evaluate any potential chronic effects on human health and the environment.

In conclusion, 2-isopropyl-4-trifluoromethylthiazole (CAS No. 916420-24-1) is a versatile compound with a wide range of applications across multiple disciplines. Its unique chemical structure, coupled with recent advancements in synthesis and application techniques, positions it as an important molecule for future innovations in materials science, pharmaceuticals, and beyond.

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