- A structure-activity relationship study of the positive allosteric modulator LY2033298 at the M4 muscarinic acetylcholine receptorSzabo, Monika; et al, MedChemComm, 2015, 6(11), 1998-2003
Cas no 91591-63-8 (2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile)
91591-63-8 structure
Product Name:2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile
CAS No:91591-63-8
MF:C8H6Cl2N2
MW:201.052639484406
MDL:MFCD00052631
CID:814464
PubChem ID:334852
Update Time:2024-10-26
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile Chemical and Physical Properties
Names and Identifiers
-
- 2,5-Dichloro-4,6-dimethylnicotinonitrile
- 2,5-Dichloro-4,6-dimethyl-3-pyridinecarbonitrile
- 2,5-dichloro-4,6-dimethylpyridine-3-carbonitrile
- 3-Pyridinecarbonitrile,2,5-dichloro-4,6-dimethyl-
- 3-Pyridinecarbonitrile, 2,5-dichloro-4,6-dimethyl-
- UCGWYTUBYASPFG-UHFFFAOYSA-N
- 2,5-dichloro-4,6-dimethyl-nicotinonitrile
- 3-Cyano-2,5-dichloro-4,6-dimethylpyridine
- NSC341973
- PubChem20434
- KSC669Q6F
- BCP18750
- DT2114
- STK724629
- SBB092706
- 2,5-Dichloro-4,6-dimethyl-3-pyridinecarbonitrile (ACI)
- 2,5-Dichloro-3-cyano-4,6-dimethylpyridine
- NSC 341973
- 2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile
- W-204063
- DTXSID50319215
- AG-205/41147734
- 3-Pyridinecarbonitrile,5-dichloro-4,6-dimethyl-
- SCHEMBL8471830
- NL7PQ926CN
- CS-0010501
- NSC-341973
- 91591-63-8
- SR-01000533931
- 2 pound not5-Dichloro-4 pound not6-dimethylnicotinonitrile
- GS-3527
- SR-01000533931-1
- SY017930
- MFCD00052631
- J-803059
- AKOS001751894
-
- MDL： MFCD00052631
- Inchi： 1S/C8H6Cl2N2/c1-4-6(3-11)8(10)12-5(2)7(4)9/h1-2H3
- InChI Key： UCGWYTUBYASPFG-UHFFFAOYSA-N
- SMILES： N#CC1C(C)=C(Cl)C(C)=NC=1Cl
Computed Properties
- Exact Mass: 199.99100
- Monoisotopic Mass: 199.9908036g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 12
- Rotatable Bond Count: 0
- Complexity: 210
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 36.7
- XLogP3: 2.9
Experimental Properties
- Density: 1.36
- Melting Point: 82-83 oC
- Boiling Point: 304.6°C at 760 mmHg
- Flash Point: 138℃
- PSA: 36.68000
- LogP: 2.87688
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile Security Information
- Signal Word：Warning
- Hazard Statement： H302-H315-H319-H335
- Warning Statement： P261-P305+P351+P338
- Hazard Category Code： R20/21/22;R36/37/38
- Safety Instruction： S26
-
Hazardous Material Identification：
- HazardClass：IRRITANT
- Storage Condition：Inert atmosphere,2-8°C(BD67504)
- Risk Phrases：R20/21/22; R36/37/38
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile Customs Data
- HS CODE：2933399090
- Customs Data：
China Customs Code:
2933399090Overview:
2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 012602-1g |
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile |
91591-63-8 | 98% | 1g |
437.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 012602-25g |
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile |
91591-63-8 | 98% | 25g |
3706.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 012602-5g |
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile |
91591-63-8 | 98% | 5g |
1105.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-HQ859-5g |
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile |
91591-63-8 | 98% | 5g |
74.0CNY | 2021-08-04 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-HQ859-1g |
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile |
91591-63-8 | 98% | 1g |
60CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-HQ859-25g |
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile |
91591-63-8 | 98% | 25g |
360CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-HQ859-100g |
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile |
91591-63-8 | 98% | 100g |
1080.0CNY | 2021-08-04 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | D841052-25g |
2,5-Dichloro-4,6-dimethylnicotinonitrile |
91591-63-8 | 98% | 25g |
￥276.30 | 2022-01-10 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-HQ859-20g |
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile |
91591-63-8 | 98% | 20g |
235.0CNY | 2021-08-04 | |
| TRC | D434275-2.5g |
2,5-Dichloro-4,6-dimethyl-3-pyridinecarbonitrile |
91591-63-8 | 2.5g |
$ 125.00 | 2022-06-05 |
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Phosphorus oxychloride ; 1 h, 100 °C
Reference
Production Method 2
Reaction Conditions
Reference
- Herbicidal 5-pyridylcyclohexane-1,3-dione derivatives, European Patent Organization, , ,
Production Method 3
Reaction Conditions
1.1 Reagents: Sulfuryl chloride Solvents: Dichloroethane ; 6 h, reflux
2.1 Reagents: Phosphorus oxychloride ; 1 h, 100 °C
2.1 Reagents: Phosphorus oxychloride ; 1 h, 100 °C
Reference
- A structure-activity relationship study of the positive allosteric modulator LY2033298 at the M4 muscarinic acetylcholine receptorSzabo, Monika; et al, MedChemComm, 2015, 6(11), 1998-2003
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile Raw materials
- 5-chloro-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
- 4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile Preparation Products
2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile Related Literature
-
Qiaoe Wang,Meiling Lian,Xiaowen Zhu,Xu Chen RSC Adv., 2021,11, 192-197
-
Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
-
Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
-
Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
-
Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
91591-63-8 (2,5-dichloro-4,6-dimethyl-pyridine-3-carbonitrile) Related Products
- 127581-38-8( )
- 65176-93-4(2-chloro-5,6-dimethyl-3-Pyridinecarbonitrile)
- 125731-30-8(2-chloro-4,5-dimethyl-3-Pyridinecarbonitrile)
- 60847-69-0(3-Pyridinecarbonitrile, 2-chloro-6-methyl-4-phenyl-)
- 14237-71-9(2-chloro-4,6-dimethylpyridine-3-carbonitrile)
- 84596-24-7(3-Pyridinecarbonitrile, 2-chloro-4,6-dimethyl-5-phenyl-)
- 28900-10-9(2-chloro-6-methylpyridine-3-carbonitrile)
- 400752-13-8(3,4-Pyridinedicarbonitrile, 2-chloro-6-phenyl-)
- 38367-36-1(2,4-dichloro-6-methyl-pyridine-3-carbonitrile)
- 63195-39-1(2,5,6-Trichloro-4-methyl-3-pyridinecarbonitrile)
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