Production Method 1

915087-25-1

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dichloromethane ;  3 h, rt

Reference

Site-Selective Silylation of Aliphatic C-H Bonds Mediated by [1,5]-Hydrogen Transfer: Synthesis of α-Sila Benzamides

Liu, Pei; et al, Organic Letters, 2016, 18(21), 5536-5539

Production Method 2

915087-24-0

915087-25-1

Reaction Conditions

1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethyl acetate ;  24 h, 2 atm, rt

Reference

A convenient synthesis of 4-amino-2-fluoro-N-methyl-benzamide

Xu, Defeng; et al, Journal of Chemical Research, 2013, 37(10), 615-616

Production Method 3

403-24-7

593-51-1

915087-25-1

Reaction Conditions

1.1 Reagents: Triethylamine ,  1,1′-Carbonyldiimidazole Solvents: Dichloromethane ;  rt; 1 h, rt
1.2 4 h, rt
2.1 Reagents: Acetic acid ,  Iron Solvents: Ethyl acetate ;  rt; 16 h, reflux

Reference

Design, synthesis, and biological evaluation of deuterated apalutamide with improved pharmacokinetic profiles

Pang, Xuehai ; et al, Bioorganic & Medicinal Chemistry Letters, 2017, 27(12), 2803-2806

4-Amino-2-fluoro-N-methylbenzamide Raw materials

• 2-Fluoro-4-nitrobenzoic acid
• 2-\u200bFluoro-\u200bN-\u200bmethyl-\u200b4-\u200bnitrobenzamide
• Methylammonium Chloride

4-Amino-2-fluoro-N-methylbenzamide Preparation Products

• 4-Amino-2-fluoro-N-methylbenzamide (915087-25-1)

• 1. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
• 2. Fe3O4@PANI: a magnetic polyaniline nanomaterial for highly efficient and handy enrichment of intact N-glycopeptides??
  Zhizhen Lai,Mo Zhang,Jinyu Zhou,Tianjing Chen,Dan Li,Xuejing Shen,Jia Liu,Jiang Zhou,Zhili Li Analyst, 2021,146, 4261-4267
• 3. Dissolution of cork biopolymers in biocompatible ionic liquids
  Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
• 4. Exciplex emission from the mixed dimer of naphthalene and 2-cyanonaphthalene in a supersonic jet
  Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
• 5. Fe3O4/PEG-SO3H as a heterogeneous and magnetically-recyclable nanocatalyst for the oxidation of sulfides to sulfones or sulfoxides
  Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Aminobenzoic acids and derivatives
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Aminobenzoic acids and derivatives
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

• 1747-80-4(2-Fluoro-N-phenyl-benzamide)
• 1153287-97-8(5-Amino-2-fluoro-N-methylbenzamide)
• 912838-60-9(Benzamide, N-ethyl-2-fluoro-4-nitro-)
• 823835-48-9(2-Fluoro-N-(3-fluoro-4-methylphenyl)benzamide)
• 869936-86-7(2-Amino-6-fluoro-N-methylbenzamide)
• 937635-68-2(2,6-difluoro-N-(3-fluorophenyl)benzamide)
• 52833-63-3(Benzamide, 2-fluoro-N-methyl-)
• 682757-75-1(5-amino-2-fluoro-N,N-dimethylbenzamide)
• 912838-61-0(4-amino-N-ethyl-2-fluorobenzamide)
• 609783-45-1(4-Amino-2-fluorobenzamide)