Cas no 913835-79-7 (3-Boronobenzohydrazide)

3-Boronobenzohydrazide is a boronic acid derivative featuring a hydrazide functional group, making it a versatile intermediate in organic synthesis and medicinal chemistry. Its key advantage lies in the presence of both boronic and hydrazide moieties, enabling its use in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures, as well as serving as a precursor for hydrazone formation. The compound exhibits good stability under standard conditions and is particularly valuable in the development of pharmaceuticals, agrochemicals, and functional materials. Its dual reactivity allows for efficient derivatization, facilitating the synthesis of complex molecules with precision. Proper handling requires adherence to standard boronic acid safety protocols.
3-Boronobenzohydrazide structure
3-Boronobenzohydrazide structure
Product Name:3-Boronobenzohydrazide
CAS No:913835-79-7
MF:C7H9BN2O3
MW:179.96896147728
MDL:MFCD08689505
CID:802844
PubChem ID:44119369
Update Time:2025-11-02

3-Boronobenzohydrazide Chemical and Physical Properties

Names and Identifiers

    • Benzoicacid, 3-borono-, hydrazide (9CI)
    • 3-(Hydrazinocarbonyl)benzeneboronic acid
    • [3-(hydrazinecarbonyl)phenyl]boronic acid
    • 3-Boronobenzohydrazide
    • OR3441
    • 3-aminocarbamoylphenylboronic acid
    • Benzoicacid,3-borono-,hydrazide(9ci)
    • MFCD08689505
    • NKQNSAXAGLKZBP-UHFFFAOYSA-N
    • 3-Boronobenzhydrazide
    • SCHEMBL1445203
    • A853745
    • 913835-79-7
    • BS-29676
    • CS-0174326
    • 3-(Hydrazinecarbonyl)benzeneboronic acid
    • AKOS006222055
    • (3-(Hydrazinecarbonyl)phenyl)boronic acid
    • DTXSID80657177
    • 3-(HYDRAZINECARBONYL)BENZENEBORONIC ACID 97
    • MDL: MFCD08689505
    • Inchi: 1S/C7H9BN2O3/c9-10-7(11)5-2-1-3-6(4-5)8(12)13/h1-4,12-13H,9H2,(H,10,11)
    • InChI Key: NKQNSAXAGLKZBP-UHFFFAOYSA-N
    • SMILES: OB(C1=CC=CC(C(NN)=O)=C1)O

Computed Properties

  • Exact Mass: 180.07100
  • Monoisotopic Mass: 180.071
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 189
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 95.6A^2

Experimental Properties

  • Density: 1.4±0.1 g/cm3
  • Melting Point: 149-151
  • Boiling Point: Not available
  • Flash Point: Not available
  • Refractive Index: 1.602
  • PSA: 95.58000
  • LogP: -0.93890
  • Vapor Pressure: Not available

3-Boronobenzohydrazide Security Information

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3-Boronobenzohydrazide Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:913835-79-7)3-Boronobenzohydrazide
Order Number:A853745
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 07:46
Price ($):729.0

Additional information on 3-Boronobenzohydrazide

3-Boronobenzohydrazide (CAS No. 913835-79-7): A Versatile Boronic Acid Derivative for Modern Applications

3-Boronobenzohydrazide (CAS No. 913835-79-7) is an emerging boronic acid derivative that has garnered significant attention in pharmaceutical research and material science. This compound, with its unique molecular structure combining a benzohydrazide moiety and a boron functional group, exhibits remarkable properties that make it valuable for various applications. Researchers are particularly interested in its potential as a building block for drug discovery and as a cross-linking agent in polymer chemistry.

The growing interest in 3-boronobenzohydrazide applications aligns with current trends in precision medicine and targeted drug delivery systems. As the pharmaceutical industry seeks more selective and efficient therapeutic agents, compounds like 3-boronobenzohydrazide offer promising possibilities due to their ability to form reversible covalent bonds with biological targets. This characteristic is especially relevant in the development of protease inhibitors and enzyme-targeted therapies, which are hot topics in contemporary medical research.

From a chemical perspective, 3-boronobenzohydrazide structure features a benzene ring substituted with both a boronic acid group (-B(OH)2) and a hydrazide functional group (-CONHNH2). This dual functionality enables diverse chemical transformations, making it a versatile intermediate in organic synthesis. The compound's molecular weight of 178.98 g/mol and its moderate solubility in polar organic solvents contribute to its handling characteristics in laboratory settings.

Recent studies on 3-boronobenzohydrazide synthesis have focused on optimizing yield and purity, with particular attention to the stability of the boronic acid group during reactions. The compound typically appears as a white to off-white crystalline powder under standard conditions, with melting point data being an important quality control parameter for industrial applications. Analytical techniques such as HPLC, NMR spectroscopy, and mass spectrometry are commonly employed to characterize this material.

In material science, the 3-boronobenzohydrazide price and availability have become increasingly important as researchers explore its use in smart materials and responsive polymers. The compound's ability to form dynamic covalent bonds makes it attractive for designing self-healing materials, a rapidly growing field that addresses sustainability concerns in manufacturing. These applications align well with current industry demands for more durable and environmentally friendly material solutions.

The pharmacological potential of 3-boronobenzohydrazide is particularly exciting in the context of cancer research and metabolic disorder treatments. While not a drug itself, this compound serves as a crucial precursor in the synthesis of various bioactive molecules. Its boronic acid group can interact with biological hydroxyl groups, enabling the design of compounds with improved target specificity - a key requirement in modern drug development paradigms.

Quality control of 3-boronobenzohydrazide CAS 913835-79-7 involves rigorous testing for impurities and verification of structural integrity. Suppliers typically provide certificates of analysis that include parameters such as purity (often ≥95% by HPLC), residual solvent content, and heavy metal limits. These specifications are crucial for researchers who require consistent performance in sensitive applications, particularly in pharmaceutical intermediate synthesis.

From a commercial perspective, the 3-boronobenzohydrazide market has seen steady growth, driven by increasing R&D activities in both academic and industrial settings. The compound's relatively stable nature under proper storage conditions (typically recommended at 2-8°C in airtight containers) contributes to its practicality as a research chemical. Current market analyses suggest growing demand from both North American and Asian research hubs.

Environmental and safety considerations for 3-boronobenzohydrazide follow standard laboratory chemical handling protocols. While not classified as highly hazardous, proper personal protective equipment including gloves and eye protection is recommended when working with this compound. Material safety data sheets provide detailed information on handling, storage, and disposal procedures to ensure safe laboratory practices.

Future research directions for 3-boronobenzohydrazide may explore its potential in bioconjugation chemistry and diagnostic agent development. The compound's ability to form stable complexes with various biomolecules opens possibilities for creating novel imaging probes or targeted delivery systems. These applications could significantly impact fields such as medical diagnostics and theranostics, which combine therapy and diagnostic capabilities.

For researchers seeking 3-boronobenzohydrazide suppliers, it's important to verify the credibility and quality standards of potential vendors. Reputable chemical suppliers typically offer detailed product specifications, batch-specific certificates of analysis, and reliable shipping options to ensure product integrity upon arrival. The global nature of chemical research means that sourcing options may vary by region, requiring careful consideration of logistics and regulatory compliance.

In conclusion, 3-Boronobenzohydrazide (CAS No. 913835-79-7) represents a fascinating example of how functional group combinations can create compounds with diverse applications. Its unique properties position it as a valuable tool in both pharmaceutical development and advanced material design. As research continues to uncover new potential uses for this boronic acid derivative, its importance in scientific and industrial contexts is likely to grow, making it a compound worth watching in the coming years.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:913835-79-7)3-Boronobenzohydrazide
A853745
Purity:99%
Quantity:25g
Price ($):729.0
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