- Investigation into Factors Influencing Stereoselectivity in the Reactions of Heterocycles with Donor-Acceptor-Substituted Rhodium CarbenoidsHedley, Simon J.; Ventura, Dominic L.; Dominiak, Paulina M.; Nygren, Cara L.; Davies, Huw M. L., Journal of Organic Chemistry, 2006, 71(14), 5349-5356
Cas no 905710-14-7 (1-Boc-5-Bromo-3-hydroxymethylindole)
905710-14-7 structure
Product Name:1-Boc-5-Bromo-3-hydroxymethylindole
CAS No:905710-14-7
MF:C14H16BrNO3
MW:326.185743331909
MDL:MFCD05864710
CID:796685
PubChem ID:40428532
Update Time:2024-10-26
1-Boc-5-Bromo-3-hydroxymethylindole Chemical and Physical Properties
Names and Identifiers
-
- 1-Boc-5-Bromo-3-hydroxymethylindole
- 1H-INDOLE-1-CARBOXYLIC ACID,5-BROMO-3-(HYDROXYMETHYL)-,1,1-DIMETHYLETHYL ESTER
- tert-Butyl 5-bromo-3-(hydroxymethyl)-1H-indole-1-carboxylate
- 5-Bromo-3-hydroxymethylindole-1-carboxylic acid tert-butyl ester
- OR1689
- 1,1-Dimethylethyl 5-bromo-3-(hydroxymethyl)-1H-indole-1-carboxylate (ACI)
- AKOS015837062
- DB-001829
- CS-0187815
- MFCD05864710
- 1H-Indole-1-carboxylicacid,5-bromo-3-(hydroxymethyl)-,1,1-dimethylethyl ester
- DTXSID90654319
- tert-butyl 5-bromo-3-(hydroxymethyl)indole-1-carboxylate
- 905710-14-7
- SCHEMBL23218891
- PS-7030
- tert-Butyl 5-bromo-3-(hydroxymethyl)-1H-indole-1-carboxylate, AldrichCPR
- tert-butyl5-bromo-3-(hydroxymethyl)-1H-indole-1-carboxylate
- 5-Bromo-3-(hydroxymethyl)indole, N-BOC protected
-
- MDL： MFCD05864710
- Inchi： 1S/C14H16BrNO3/c1-14(2,3)19-13(18)16-7-9(8-17)11-6-10(15)4-5-12(11)16/h4-7,17H,8H2,1-3H3
- InChI Key： LPXSZZFLLCBIJX-UHFFFAOYSA-N
- SMILES： O=C(N1C2C(=CC(=CC=2)Br)C(CO)=C1)OC(C)(C)C
Computed Properties
- Exact Mass: 325.03100
- Monoisotopic Mass: 325.03136g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 19
- Rotatable Bond Count: 4
- Complexity: 342
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3.1
- Topological Polar Surface Area: 51.5?2
Experimental Properties
- Density: 1.43
- Boiling Point: 442.078°C at 760 mmHg
- Flash Point: 221.161°C
- Refractive Index: 1.586
- PSA: 51.46000
- LogP: 3.67930
1-Boc-5-Bromo-3-hydroxymethylindole Customs Data
- HS CODE：2933990090
- Customs Data：
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
1-Boc-5-Bromo-3-hydroxymethylindole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 076624-1g |
1-Boc-5-Bromo-3-hydroxymethylindole |
905710-14-7 | 95% | 1g |
￡57.00 | 2022-03-01 | |
| Fluorochem | 076624-10g |
1-Boc-5-Bromo-3-hydroxymethylindole |
905710-14-7 | 95% | 10g |
￡250.00 | 2022-03-01 | |
| Fluorochem | 076624-25g |
1-Boc-5-Bromo-3-hydroxymethylindole |
905710-14-7 | 95% | 25g |
￡625.00 | 2022-03-01 | |
| TRC | B643955-100mg |
1-Boc-5-bromo-3-hydroxymethylindole |
905710-14-7 | 100mg |
$ 64.00 | 2023-04-18 | ||
| TRC | B643955-250mg |
1-Boc-5-bromo-3-hydroxymethylindole |
905710-14-7 | 250mg |
$ 75.00 | 2023-04-18 | ||
| TRC | B643955-500mg |
1-Boc-5-bromo-3-hydroxymethylindole |
905710-14-7 | 500mg |
$ 87.00 | 2023-04-18 | ||
| TRC | B643955-1g |
1-Boc-5-bromo-3-hydroxymethylindole |
905710-14-7 | 1g |
$ 98.00 | 2023-04-18 | ||
| Matrix Scientific | 071726-1g |
1-Boc-5-Bromo-3-hydroxymethylindole, 95+% |
905710-14-7 | 95+% | 1g |
$162.00 | 2023-09-09 | |
| Matrix Scientific | 071726-5g |
1-Boc-5-Bromo-3-hydroxymethylindole, 95+% |
905710-14-7 | 95+% | 5g |
$399.00 | 2023-09-09 | |
| Matrix Scientific | 071726-10g |
1-Boc-5-Bromo-3-hydroxymethylindole, 95+% |
905710-14-7 | 95+% | 10g |
$536.00 | 2023-09-09 |
1-Boc-5-Bromo-3-hydroxymethylindole Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Sodium borohydride Solvents: Ethanol ; 6 h, rt
Reference
Production Method 2
Reaction Conditions
1.1 Catalysts: 4-(Dimethylamino)pyridine Solvents: Acetonitrile ; rt
1.2 Reagents: Sodium borohydride Solvents: Methanol ; 0 °C
1.2 Reagents: Sodium borohydride Solvents: Methanol ; 0 °C
Reference
- Gold-catalyzed intermolecular reaction of ynamides with 3-indolyl azides via an unexpected 1,2-alkyl migrationZhou, Bo; Zhang, Ying-Qi; Liu, Xin; Ye, Long-Wu, Science Bulletin, 2017, 62(17), 1201-1206
1-Boc-5-Bromo-3-hydroxymethylindole Raw materials
- 5-Bromo-1H-indole-3-carbaldehyde
- Di-tert-butyl dicarbonate
- tert-Butyl 5-Bromo-3-formyl-1H-indole-1-carboxylate
1-Boc-5-Bromo-3-hydroxymethylindole Preparation Products
1-Boc-5-Bromo-3-hydroxymethylindole Related Literature
-
Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
-
Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
-
Sandip Gangadhar Balwe,Yeon Tae Jeong Org. Biomol. Chem., 2018,16, 1287-1296
-
P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
905710-14-7 (1-Boc-5-Bromo-3-hydroxymethylindole) Related Products
- 303041-88-5(1-Boc-4-Bromo-3-formylindole)
- 914349-03-4(tert-Butyl 3-(Hydroxymethyl)-5-methyl-1H-indole-1-carboxylate)
- 852180-98-4(1H-Indole-1,3-dicarboxylicacid, 5-bromo-, 1-(1,1-dimethylethyl) ester)
- 325800-39-3(tert-Butyl 5-Bromo-3-formyl-1H-indole-1-carboxylate)
- 914349-05-6(1-Boc-4-Bromo-3-hydroxymethylindole)
- 93862-70-5(1H-Indole-1-carboxylic acid, 6-bromo-3-formyl-, 1,1-dimethylethyl ester)
- 914349-04-5(Tert-Butyl 3-(hydroxymethyl)-6-methyl-1H-indole-1-carboxylate)
- 914349-11-4(1-Boc-5-Cyano-3-hydroxymethylindole)
- 914349-10-3(Tert-Butyl 3-(hydroxymethyl)-7-methyl-1H-indole-1-carboxylate)
- 89378-43-8(tert-Butyl 3-Methyl-1H-indole-1-carboxylate)
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