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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolopyrimidines Pyrrolo[2,3-d]pyrimidines

Comprehensive Overview of 4-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS No. 90358-16-0)

The compound 4-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS No. 90358-16-0) is a heterocyclic organic molecule that has garnered significant attention in pharmaceutical and agrochemical research. Its unique structure, featuring a pyrrolopyrimidine core, makes it a valuable intermediate in the synthesis of bioactive molecules. Researchers are particularly interested in its potential applications in kinase inhibition and cancer therapeutics, aligning with the growing demand for targeted drug discovery.

In recent years, the search for novel small-molecule inhibitors has intensified, driven by advancements in precision medicine. The 4-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine scaffold is often explored due to its ability to modulate key enzymatic pathways. This aligns with trending topics such as personalized cancer treatment and AI-driven drug design, where computational tools predict the efficacy of such compounds. Its chloro and methyl substituents further enhance its reactivity, making it a versatile building block.

From a synthetic chemistry perspective, the compound’s CAS No. 90358-16-0 is frequently referenced in patent literature and academic journals. Its role in constructing ATP-competitive inhibitors is well-documented, addressing the need for kinase-targeted therapies in diseases like rheumatoid arthritis and oncology. The rise of fragment-based drug discovery has also spotlighted this molecule, as its compact size allows for efficient optimization in lead compound development.

Beyond pharmaceuticals, 4-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine finds utility in agrochemical research, particularly in designing herbicides and pesticides with improved selectivity. This resonates with global discussions on sustainable agriculture and eco-friendly pest control, where low-toxicity alternatives are prioritized. The compound’s stability under various conditions further supports its industrial applicability.

Analytical studies of CAS No. 90358-16-0 often highlight its spectroscopic properties, such as NMR and mass spectrometry profiles, which are critical for quality control in manufacturing. The integration of machine learning in chemical analysis has streamlined the characterization of such compounds, a topic frequently searched by chemists and data scientists alike.

In summary, 4-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine represents a multifaceted tool in modern chemistry. Its relevance to drug discovery, agricultural innovation, and computational chemistry ensures its continued prominence in scientific discourse. As research evolves, this compound is poised to play a pivotal role in addressing pressing challenges in health and sustainability.

• 24391-41-1(4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile)
• 908287-21-8(4-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde)
• 1618-36-6(4-Chloro-5-methyl-7H-pyrrolo[2,3-D]pyrimidine)
• 651035-58-4(1H-Pyrrolo[2,3-d]pyrimidin-2-amine, 4-chloro-, monosodium salt)
• 124738-81-4(2-amino-4-chloro-7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile)
• 1004992-44-2(4-Chloro-5-ethyl-7H-pyrrolo[2,3-d]pyrimidine)
• 1060815-86-2(2,4-Dichloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine)
• 181480-32-0(4-chloro-5,7-dimethyl-7H-Pyrrolo[2,3-d]pyrimidin-2-amine)
• 84955-31-7(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine)
• 1207543-24-5({4-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl}methanol)