Cas no 899827-82-8 (6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one)

6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one structure

899827-82-8 structure

Product Name:6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one

CAS No:899827-82-8

MF:C₁₀H₁₂FN₅O₄

MW:285.231784820557

CID:2952394

Update Time:2023-11-10

6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one Chemical and Physical Properties

Names and Identifiers

- 6-氨基-9-(2-脫氧-2-氟-BETA-D-阿拉伯呋喃糖基)-1,9-二氫-2H-嘌呤-2-酮
- 6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one
- 6-Amino-9-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-2-one
- 2'-DEOXY-2'-FLUORO-ARABINOISOGUANOSINE
- F12907
- A855511
- 2H-Purin-2-one, 6-amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro- (9CI)
- 6-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,9-dihydro-2H-purin-2-one (ACI)
- Inchi： 1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(12)14-10(19)15-8(5)16/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4+,6-,9-/m1/s1
- InChI Key： SRUXNNJIKBFXNW-AYQXTPAHSA-N
- SMILES： NC1=NC(=O)NC2N([C@H]3[C@@H](F)[C@H](O)[C@@H](CO)O3)C=NC1=2

Computed Properties

Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 7
Heavy Atom Count: 20
Rotatable Bond Count: 2
Complexity: 548
XLogP3: -2
Topological Polar Surface Area: 133

6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Alichem	A159002593-5mg	6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one	899827-82-8	97%	5mg	$1058.40	2023-08-31
Alichem	A159002593-10mg	6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one	899827-82-8	97%	10mg	$1831.50	2023-08-31
Chemenu	CM261478-10mg	6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one	899827-82-8	97%	10mg	$***	2023-05-29

6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one Production Method

Production Method 1

123318-82-1

899827-82-8

Reaction Conditions

1.1 Reagents: Lithium hydroxide , Hydrogen peroxide Solvents: Water ; 24 h, 60 °C
1.2 Reagents: Sodium thiosulfate Solvents: Water
1.3 Reagents: Acetic acid ; pH 4 - 5

Reference

: Isolation, Synthesis, and Characterization of Impurities and Degradants from the Clofarabine Process

Anderson, Bruce G.; Bauta, William E.; Cantrell, William R. Jr.; Engles, Tracy; Lovett, Dennis P., Organic Process Research & Development, 2008, 12(6), 1229-1237

Production Method 2

123318-82-1

899827-82-8

Reaction Conditions

1.1 Reagents: Lithium hydroxide , Hydrogen peroxide Solvents: Water ; 24 h, 60 °C
1.2 Reagents: Sodium thiosulfate Solvents: Water
1.3 Reagents: Acetic acid Solvents: Water ; pH 4 - 5

Reference

: Hydrogen peroxide promoted hydroxylation of halo arenes and heteroarenes

Cantrell, William R.; Bauta, William E.; Engles, Tracy, Tetrahedron Letters, 2006, 47(25), 4249-4251

6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one Raw materials

Clofarabine

6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one Preparation Products

6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one (899827-82-8)

6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one Suppliers

NewCan Biotech Limited

Gold Member

Audited Supplier

(CAS:899827-82-8)2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine

Order Number:NC14198

Stock Status:

Quantity:10g

Purity:97%

Pricing Information Last Updated:Friday, 18 July 2025 16:01

Price ($):Price inquiry

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899827-82-8 (6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one) Related Products

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