Production Method 1

66572-56-3

925-93-9

89978-52-9

Reaction Conditions

1.1 Reagents: Thionyl chloride Solvents: Ethanol-d ;  0 °C; 0 °C → reflux; overnight, reflux

Reference

Discovery of a new class of JMJD6 inhibitors and structure-activity relationship study

Wang, Tianqi; Zhang, Rong; Liu, Yang ; Fang, Zhen ; Zhang, Hailin; et al, Bioorganic & Medicinal Chemistry Letters, 2021, 44,

Production Method 2

66572-56-3

89978-52-9

Reaction Conditions

1.1 Reagents: Sulfuric acid Solvents: Ethanol ;  24 h, 90 °C
1.2 Reagents: Potassium carbonate Solvents: Water ;  pH 7

Reference

Synthesis and Characterization of a Series of Bis-homoleptic Cycloruthenates with Terdentate Ligands as a Family of Panchromatic Dyes

Rees, Thomas W.; Liao, Jin Feng; Sinopoli, Alessandro; Male, Louise; Calogero, Giuseppe; et al, Inorganic Chemistry, 2017, 56(16), 9903-9912

Production Method 3

66572-56-3

89978-52-9

Reaction Conditions

Reference

Design, synthesis and biological evaluation as immunosuppressant of amino alcohol derivatives containing thioether

Li, Yanjie; Li, Yongqiang; Yang, Liu; Liu, Zhi; Zhang, Ruimeng; et al, Materials Express, 2021, 11(5), 773-780

Production Method 4

66572-56-3

89978-52-9

Reaction Conditions

1.1 Catalysts: Sulfuric acid Solvents: Ethanol ;  3 h, reflux
1.2 Reagents: Sodium bicarbonate Solvents: Water

Reference

Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL)

Mayer, Nicole; Schweiger, Martina; Fuchs, Elisabeth; Migglautsch, Anna K.; Doler, Carina; et al, Bioorganic & Medicinal Chemistry, 2020, 28(16),

Production Method 5

66572-56-3

89978-52-9

Reaction Conditions

Reference

Synthesis and biological evaluation of 4-carbamoyl-2-β-D-ribofuranosylpyridine

Joos, Pieter E.; Esmans, Eddy L.; Dommisse, Roger A.; Van Dongen, Walter; Lepoivre, Jozef A.; et al, Nucleosides & Nucleotides, 1991, 10(4), 883-94

Ethyl 2-bromoisonicotinate Raw materials

• 2-bromopyridine-4-carboxylic acid
• Ethanol-d

Ethyl 2-bromoisonicotinate Preparation Products

• Ethyl 2-bromoisonicotinate (89978-52-9)

• 1. An alumina stabilized graphene oxide wrapped SnO2 hollow sphere LIB anode with improved lithium storage?
  Xiang Liu,Qian Sun,A. B. Djuri?i?,Maohai Xie,Baohu Dai,Jinyao Tang,Charles Surya,Changzhong Liao,Kaimin Shih RSC Adv., 2015,5, 100783-100789
• 2. An integrated microfluidic platform for sensitive and rapid detection of biological toxins?
  Robert J. Meagher,Anson V. Hatch,Ronald F. Renzi,Anup K. Singh Lab Chip, 2008,8, 2046-2053
• 3. An intensified π-hole in beryllium-doped boron nitride meshes: its determinant role in CO2 conversion into hydrocarbon fuels?
  Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
• 4. An insight into the origin of room-temperature ferromagnetism in SnO2 and Mn-doped SnO2 quantum dots: an experimental and DFT approach?
  Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
• 5. An integrated droplet-digital microfluidic system for on-demand droplet creation, mixing, incubation, and sorting?
  Lab Chip, 2019,19, 524-535

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Pyridinecarboxylic acids

• 2016-99-1(2,6-dibromopyridine-4-carboxylic acid)
• 26156-48-9(Methyl 2-bromoisonicotinate)
• 26218-78-0(methyl 6-bromopyridine-3-carboxylate)
• 132334-98-6(6-Bromo Nicotinic Acid Ethyl Ester)
• 1227575-00-9(Methyl 2-bromo-5-methylpyridine-4-carboxylate)
• 66572-56-3(2-bromopyridine-4-carboxylic acid)
• 25462-90-2(ethyl 2-broMo-6-Methylisonicotinate)
• 119308-57-5(Methyl 2,6-dibromopyridine-4-carboxylate)
• 90050-70-7(ethyl 2,6-dibromopyridine-4-carboxylate)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)