Production Method 1

931-78-2

89854-70-6

Reaction Conditions

1.1 Catalysts: Benzene Solvents: Benzene
1.2 Reagents: Triethyl phosphite ,  Azidotrimethylsilane ,  Hydrochloric acid Solvents: Benzene

Reference

A simple, one-pot transformation of tert-alkyl chlorides into (tert-alkyl)amines

Koziara, Anna; Osowska-Pacewicka, Krystyna; Zawadzki, Stefan; Zwierzak, Andrzej, Synthesis, 1987, (5), 487-9

Production Method 2

1133989-31-7

89854-70-6

31562-43-3

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Cyclopentyl methyl ether ;  1.5 h, 5 °C; 1 h, 23 °C

Reference

Recycling the tert-Butanesulfinyl Group in the Synthesis of Amines Using tert-Butanesulfinamide

Wakayama, Masakazu; Ellman, Jonathan A., Journal of Organic Chemistry, 2009, 74(7), 2646-2650

Production Method 3

108-87-2

89854-70-6

Reaction Conditions

1.1 Reagents: Benzophenone imine ,  3H-1,2-Benziodoxole, 1-methoxy-3,3-dimethyl- ;  24 h, 75 °C
1.2 Reagents: Hydrochloric acid Solvents: Methanol ,  Water ;  24 h, 45 °C
1.3 Reagents: Sodium hydroxide Solvents: Water ;  pH 13, rt
1.4 Reagents: Hydrochloric acid Solvents: Diethyl ether ,  Methanol ;  acidified, rt

Reference

One-Pot Synthesis of Primary and Secondary Aliphatic Amines via Mild and Selective sp3 C-H Imination

Ghosh, Subrata K. ; Hu, Mengnan ; Comito, Robert J., Chemistry - A European Journal, 2021, 27(70), 17601-17608

Production Method 4

1123-24-6

89854-70-6

Reaction Conditions

1.1 Reagents: Potassium hydroxide ,  Bromine Solvents: Water
1.2 Reagents: Hydrochloric acid Solvents: Water

Reference

Conformational equilibria involving 2-amino-1,3-dioxans: steric control of the anomeric effect

Kirby, Anthony J.; Wothers, Peter D., ARKIVOC [online computer file], 2001, 2(12),

Production Method 5

1133989-31-7

89854-70-6

146374-27-8

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Cyclopentyl methyl ether ;  2.5 h, 5 °C → rt
1.2 Reagents: Ammonium hydroxide Solvents: Cyclopentyl methyl ether ;  2 h, -10 °C → rt

Reference

Cyclopentyl methyl ether (CPME)

Watanabe, Kiyoshi; Torisawa, Yasuhiro, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2013, 1, 1-2

Production Method 6

583-60-8

89854-70-6

15963-35-6

Reaction Conditions

Reference

Lithium aluminium hydride reduction of methylcyclohexanones

Dauben, Wm. G.; Bozak, Richard E., Journal of Organic Chemistry, 1959, 24, 1596-7

1-Methylcyclohexan-1-amine Hydrochloride Raw materials

• Cyclohexane,1-chloro-1-methyl-
• Methylcyclohexane
• N-(1-methylcyclohexyl)-tert-butanesulfinamide
• 2-Methylcyclohexanone
• 1-Methylcyclohexanecarboxamide

1-Methylcyclohexan-1-amine Hydrochloride Preparation Products

• tert-Butylsulfinamide (146374-27-8)
• 2-Methylpropane-2-sulfinic Chloride (31562-43-3)
• Cyclohexanol, 2-methyl-, (1S,2R)- (15963-35-6)
• 1-Methylcyclohexan-1-amine Hydrochloride (89854-70-6)

• 1. An approach for correlating the structural and electrical properties of Zr4+-modified SrBi4Ti4O15/SBT ceramic
  Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
• 2. An apparatus for determining small amounts of alchohol in sour milk and urine
  Analyst, 1964,89, 272-275
• 3. An atomistic mechanism for the degradation of perovskite solar cells by trapped charge?
  Eunhak Lim,Jiyoung Heo,Seong Keun Kim Nanoscale, 2019,11, 11369-11378
• 4. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
• 5. An asymmetric supercapacitor based on controllable WO3 nanorod bundle and alfalfa-derived porous carbon?
  Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642

• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Cyclohexylamines

• 665-66-7(Amantadine hydrochloride)
• 1255099-50-3(Cis-1-Butyl-4-methylcyclohexylamine HCl)
• 41100-52-1(Memantine hydrochloride)
• 26562-81-2(adamantane-1,3-diamine;dihydrochloride)
• 18392-94-4([1,1'-Bitricyclo[3.3.1.13,7]decane]-1,1'-diamine,hydrochloride (1:2))
• 13878-11-0(1-Adamantanamine,hydrochloride.(L-)- (8CI))
• 2277-93-2(bicyclo2.2.2octane-1,4-diamine Dihydrochloride)
• 75934-56-4(norbornan-1-amine;hydrochloride)
• 1255098-84-0(cis-1,4-Dimethyl-cyclohexylamine hydrochloride)
• 61278-98-6(N-ethylcyclohexanamine hydrochloride)