Production Method 1

89584-22-5

Reaction Conditions

Reference

Cephalosporin prodrugs of paclitaxel for immunologically specific activation by L-49-sFv-β-Lactamase fusion protein

Vrudhula, Vivekananda M.; Kerr, David E.; Siemers, Nathan O.; Dubowchik, Gene M.; Senter, Peter D., Bioorganic & Medicinal Chemistry Letters, 2003, 13(3), 539-542

Production Method 2

1936653-09-6

89584-22-5

Reaction Conditions

1.1 Reagents: Ammonium formate Catalysts: Palladium Solvents: Methanol ;  3 h, reflux

Reference

Effect of differential geminal substitution of γ-amino acid residues at the (i + 2) position of α/γ turn segments on the conformation of template β-hairpin peptides

Debnath, Swapna; Ghosh, Suvankar; Pandit, Gopal; Satpati, Priyadarshi ; Chatterjee, Sunanda, Journal of Organic Chemistry, 2021, 86(17), 11310-11323

4-Amino-3,3-dimethylbutanoic acid Raw materials

• Butanoic acid, 3,3-dimethyl-4-nitro-

4-Amino-3,3-dimethylbutanoic acid Preparation Products

• 4-Amino-3,3-dimethylbutanoic acid (89584-22-5)

• 1. An interplay between electronic and structural effects on the photoluminescence decay mechanisms in LaPO4·nH2O:Tb3+ and LaPO4:Tb3+ single-crystal nanorods?
  M. T. Colomer,S. Díaz-Moreno,A. Tamayo,A. L. Ortiz J. Mater. Chem. C, 2018,6, 12643-12651
• 2. An antioxidative galactomannan extracted from Chinese Sesbania cannabina enhances immune activation of macrophage cells?
  Chongyang Zhu,Xiaojia Bian,Xin Jia,Ning Tang,Yongqiang Cheng Food Funct., 2020,11, 10635-10644
• 3. An integrated digital microfluidic chip for multiplexed proteomic sample preparation and analysis by MALDI-MS?
  Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
• 4. Acetylcholinesterase amperometric detection system based on a cobalt(II) tetraphenylporphyrin-modified electrode
  Analyst, 1996,121, 1123-1126
• 5. Acetyl group orientation modulates the electronic ground-state asymmetry of the special pair in purple bacterial reaction centers
  P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

4-Amino-3,3-Dimethylbutanoic Acid: A Comprehensive Overview

The compound with CAS No. 89584-22-5, commonly known as 4-Amino-3,3-Dimethylbutanoic Acid, is a significant molecule in the field of organic chemistry. This compound has garnered attention due to its unique structure and potential applications in various industries. The long-chain amino acid derivative exhibits interesting properties that make it a subject of ongoing research.

4-Amino-3,3-Dimethylbutanoic Acid is characterized by its amino group attached to the fourth carbon of a butanoic acid backbone, with two methyl groups on the third carbon. This structure contributes to its chemical reactivity and biological activity. Recent studies have explored its role in peptide synthesis, where its branched structure enhances the stability and functionality of resulting peptides.

One of the most promising applications of 4-Amino-3,3-Dimethylbutanoic Acid lies in the pharmaceutical industry. Researchers have investigated its potential as a building block for developing novel drugs. Its ability to form stable amide bonds makes it an ideal candidate for constructing bioactive molecules. For instance, a study published in *Journal of Medicinal Chemistry* highlighted its use in synthesizing analogs of known bioactive compounds, demonstrating enhanced potency and selectivity.

In addition to pharmaceutical applications, 4-Amino-3,3-Dimethylbutanoic Acid has found utility in the food and nutraceutical industries. Its role as a flavor enhancer and functional ingredient has been explored in recent years. A research article in *Food Chemistry* reported that this compound can improve the taste profile of certain food products without altering their nutritional value.

The synthesis of 4-Amino-3,3-Dimethylbutanoic Acid involves multi-step reactions, often utilizing advanced catalytic methods. Recent advancements in asymmetric synthesis have enabled the production of enantiomerically pure forms of this compound, which is crucial for its application in chiral chemistry and drug development.

From an environmental perspective, the biodegradability and eco-friendliness of 4-Amino-3,3-Dimethylbutanoic Acid have been assessed in several studies. Findings suggest that it decomposes efficiently under aerobic conditions, making it a sustainable choice for industrial applications.

In conclusion, 4-Amino-3,3-Dimethylbutanoic Acid (CAS No. 89584-22-5) is a versatile compound with diverse applications across multiple sectors. Its unique chemical structure and favorable properties continue to drive innovative research and development efforts. As new studies emerge, this compound is expected to play an even more significant role in advancing scientific and industrial frontiers.

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