Cas no 89464-63-1 (DMOG)

DMOG structure
DMOG structure
Product Name:DMOG
CAS No:89464-63-1
MF:C6H9NO5
MW:175.139362096786
MDL:MFCD05865098
CID:722471
PubChem ID:329798774
Update Time:2024-10-26

DMOG Chemical and Physical Properties

Names and Identifiers

    • Glycine,N-(2-methoxy-2-oxoacetyl)-, methyl ester
    • Dimethyloxaloylglycine
    • DMOG
    • Dimethyloxallyl Glycine
    • Dimethyloxaloylglycine (DMOG)
    • Dimethyloxalylglycine
    • methyl 2-[(2-methoxy-2-oxoethyl)amino]-2-oxoacetate
    • N-(2-methoxy-2-oxoacetyl)Glycine methyl ester
    • N-(Methoxyoxoacetyl)-glycine methyl ester
    • N-[Methoxy(oxo)acetyl]glycine Methyl Ester
    • N-[(Methoxycarbonyl)methyl]oxamic acid methyl ester
    • methyl 2-((2-methoxy-2-oxoethyl)amino)-2-oxoacetate
    • BNJOZDZCRHCODO-UHFFFAOYSA-N
    • Glycine, N-(methoxyoxoacetyl)-, methyl ester
    • METHYL 2-(2-METHOXY-2-OXOETHYLAMINO)-2-OXOACETATE
    • methyl n-[methoxy(oxo)acetyl]glycinate
    • dimethyl oxalylglycine
    • methyl 2-(2-methoxy-2-oxoacetamido)acetate
    • Dimethy
    • Glycine, N-(methoxyoxoacetyl)-, methyl ester (9CI)
    • Oxamic acid, (carboxymethyl)-, dimethyl ester (7CI)
    • 2: PN: US6833489 FIGURE: 1 claimed protein
    • MDL: MFCD05865098
    • Inchi: 1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h3H2,1-2H3,(H,7,9)
    • InChI Key: BNJOZDZCRHCODO-UHFFFAOYSA-N
    • SMILES: O=C(C(NCC(OC)=O)=O)OC

Computed Properties

  • Exact Mass: 175.04800
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 5
  • Complexity: 200
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 2
  • XLogP3: -0.3
  • Topological Polar Surface Area: 81.7

Experimental Properties

  • Color/Form: Not available
  • Density: 1.246±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 49.0 to 53.0 deg-C
  • Boiling Point: 182°C/12mmHg(lit.)
  • Solubility: Dissolution (67 g/l) (25 o C),
  • Water Partition Coefficient: Soluble in water at 30mg/ml.
  • PSA: 81.70000
  • LogP: -1.16050
  • Solubility: Not available

DMOG Security Information

  • Symbol: GHS07
  • Signal Word:Warning
  • Hazard Statement: H302
  • Warning Statement: P301+P312+P330
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 22
  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT
  • Storage Condition:Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

DMOG Customs Data

  • HS CODE:2924199090
  • Customs Data:

    China Customs Code:

    2924199090

    Overview:

    2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

DMOG Pricemore >>

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DMOG Production Method

Production Method 1

Reaction Conditions
Reference
Preparation of oxalylamino acid derivatives as proline and lysine hydroxylase inhibitors.
, Germany, , ,

Production Method 2

Reaction Conditions
1.1 Reagents: Triethylamine Solvents: Toluene ;  5 h, reflux
Reference
Triflic anhydride-mediated synthesis of oxazoles
Thalhammer, Armin; Mecinovic, Jasmin; Schofield, Christopher J., Tetrahedron Letters, 2009, 50(9), 1045-1047

Production Method 3

Reaction Conditions
1.1 Solvents: Toluene
Reference
Novel inhibitors of prolyl 4-hydroxylase. 3. Inhibition by the substrate analog N-oxaloglycine and its derivatives
Cunliffe, C. Jane; Franklin, Trevor J.; Hales, Neil J.; Hill, George B., Journal of Medicinal Chemistry, 1992, 35(14), 2652-8

DMOG Raw materials

DMOG Preparation Products

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