- Chemistry of Covalent Inhibition of the Gastric (H+, K+)-ATPase by Proton Pump InhibitorsShin, Jai Moo; Cho, Young Moon; Sachs, George, Journal of the American Chemical Society, 2004, 126(25), 7800-7811
Cas no 89352-76-1 ((5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole)
89352-76-1 structure
Product Name:(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole
CAS No:89352-76-1
MF:C18H21N3O3S
MW:359.44264292717
CID:854383
PubChem ID:5324591
Update Time:2024-10-26
(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole Chemical and Physical Properties
Names and Identifiers
-
- N-Methyl OMeprazole (Mixture of isoMers with the Methylated nitrogens of iMidazole)
- 5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1-methyl-1H-benzo[d]imidazole
- 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1-methylbenzimidazole,6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1-methylbenzimidazole
- N-Methyl Omeprazole
- N-Methyl Omeprazole (Mixture of isomers with the methylated nitrogens of imidazole)
- 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1-methyl-, (±)- (ZCI)
- 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1-methyl-1H-benzimidazole (ACI)
- Esomeprazole Impurity 11（Mixture of Isomers）
- (5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole
- VAK4E4QKJ4
- CS-0197480
- 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1-methyl-1H-benzimidazole
- (S)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1-methyl-1H-benzo[d]imidazole
- UNII-VAK4E4QKJ4
- CHEMBL4589446
- BS-50563
- AC-30004
- SCHEMBL2592828
- N-METHYLOMEPRAZOLE
- 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1-methyl-1H-benzimidazole
- 89352-76-1
- 1H-benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1-methyl-
- DS-015878
- 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1-methyl-1H-1,3-benzodiazole
- 1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1-methyl-
- 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1-methylbenzimidazole
- 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1-methyl-1,3-benzodiazole
-
- MDL： N/A
- Inchi： 1S/C18H21N3O3S/c1-11-9-19-15(12(2)17(11)24-5)10-25(22)18-20-14-8-13(23-4)6-7-16(14)21(18)3/h6-9H,10H2,1-5H3
- InChI Key： RUGQJBJNYIHOIW-UHFFFAOYSA-N
- SMILES： O=S(CC1C(C)=C(OC)C(C)=CN=1)C1N(C)C2C(=CC(=CC=2)OC)N=1
Computed Properties
- Exact Mass: 359.13036271g/mol
- Monoisotopic Mass: 359.13036271g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 12
- Heavy Atom Count: 50
- Rotatable Bond Count: 10
- Complexity: 481
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.2
- Topological Polar Surface Area: 85.4?2
Experimental Properties
- Density: 1.30
- Melting Point: 132-135°C
- Boiling Point: NA
(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole Security Information
- Hazard Statement： CAUTION: May irritate eyes, skin
- Safety Instruction： CAUT
(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM161280-100mg |
5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1-methyl-1H-benzo[d]imidazole |
89352-76-1 | 95% | 100mg |
$636 | 2021-08-05 | |
| Ambeed | A638530-100mg |
N-Methyl Omeprazole |
89352-76-1 | 95% | 100mg |
$134.0 | 2025-04-15 | |
| Ambeed | A638530-1g |
N-Methyl Omeprazole |
89352-76-1 | 95% | 1g |
$504.0 | 2025-04-15 | |
| Ambeed | A638530-50mg |
N-Methyl Omeprazole |
89352-76-1 | 95% | 50mg |
$97.0 | 2025-04-15 | |
| Ambeed | A638530-250mg |
N-Methyl Omeprazole |
89352-76-1 | 95% | 250mg |
$198.0 | 2025-04-15 | |
| BAI LING WEI Technology Co., Ltd. | 1189592-100MG |
N-Methyl omeprazole, 98%, mixture of isomers with the methylated nitrogens of imidazole |
89352-76-1 | 98% | 100MG |
￥ 1995 | 2022-04-26 | |
| BAI LING WEI Technology Co., Ltd. | 1189592-500MG |
N-Methyl omeprazole, 98%, mixture of isomers with the methylated nitrogens of imidazole |
89352-76-1 | 98% | 500MG |
￥ 7980 | 2022-04-26 | |
| Chemenu | CM161280-250mg |
5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1-methyl-1H-benzo[d]imidazole |
89352-76-1 | 95% | 250mg |
$*** | 2023-05-29 | |
| Chemenu | CM161280-1g |
5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1-methyl-1H-benzo[d]imidazole |
89352-76-1 | 95% | 1g |
$*** | 2023-05-29 | |
| eNovation Chemicals LLC | Y1214703-1g |
N-Methyl Omeprazole |
89352-76-1 | 95% | 1g |
$1000 | 2024-07-23 |
(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: 1,8-Diazabicyclo[5.4.0]undec-7-ene Solvents: Dichloromethane ; rt
1.2 Solvents: Water ; 30 min, rt
1.2 Solvents: Water ; 30 min, rt
Reference
Production Method 2
Reaction Conditions
1.1 Catalysts: Iron(III) acetylacetonate , 2,4-Dichloro-6-[(E)-[[(1S)-1-(hydroxymethyl)-2,2-dimethylpropyl]imino]methyl]phe… Solvents: Ethyl acetate ; 30 min, 25 °C
1.2 Reagents: Benzoic acid, 4-(dimethylamino)-, lithium salt (1:1) Solvents: Ethyl acetate ; 30 min, 25 °C
1.3 Reagents: Hydrogen peroxide Solvents: Ethyl acetate ; -7 °C; 2 min, -7 °C; 5.5 h, -7 °C
1.2 Reagents: Benzoic acid, 4-(dimethylamino)-, lithium salt (1:1) Solvents: Ethyl acetate ; 30 min, 25 °C
1.3 Reagents: Hydrogen peroxide Solvents: Ethyl acetate ; -7 °C; 2 min, -7 °C; 5.5 h, -7 °C
Reference
- Synthesis of Esomeprazole and Related Proton Pump Inhibitors through Iron-Catalyzed Enantioselective SulfoxidationNishiguchi, Shigenobu; Izumi, Takuhiro; Kouno, Takayoshi; Sukegawa, Junpei; Ilies, Laurean ; et al, ACS Catalysis, 2018, 8(10), 9738-9743
(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole Raw materials
- Omeprazole
- 6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1-methyl-1H-benzimidazole
- 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1-methyl-
(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole Preparation Products
(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:89352-76-1)(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole
Order Number:A901451
Stock Status:in Stock
Quantity:250mg/1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 12:08
Price ($):162.0/412.0
Email:[email protected]
(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole Related Literature
-
Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
-
Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
-
Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
-
M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
89352-76-1 ((5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole) Related Products
- 95382-33-5(Omeprazole magnesium)
- 95510-70-6(Omeprazole sodium)
- 161973-10-0(Esomeprazole Magnesium)
- 151602-49-2(5-O-Desmethyl Omeprazole)
- 73590-58-6(Omeprazole)
- 935260-92-7(N-4-(3-Methoxypropoxy)-3-methyl-2-pyridinylmethyl Rabeprazole)
- 119141-88-7(6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole)
- 161796-78-7((S)-Omeprazole Sodium Salt)
- 119141-89-8((r)-Omeprazole)
- 217087-09-7(Esomeprazole magnesium trihydrate)
Recommended suppliers
Amadis Chemical Company Limited
(CAS:89352-76-1)(5-Desmethoxy-6-methoxy) 1-N-Methyl Omeprazole
Purity:99%/99%
Quantity:250mg/1g
Price ($):162.0/412.0