Production Method 1

58267-85-9

89324-44-7

Reaction Conditions

1.1 Reagents: Butyllithium ,  N,N,N′,N′-Tetramethylethylenediamine Solvents: Tetrahydrofuran ,  Hexane ;  -78 °C; 2 h, -78 °C
1.2 1 h, -78 °C; overnight, rt
1.3 Reagents: Sulfuric acid Solvents: Water ;  3 h, rt

Reference

Enantioselective Rhodium-Catalyzed Dimerization of ω-Allenyl Carboxylic Acids: Straightforward Synthesis of C2-Symmetric Macrodiolides

Steib, Philip; Breit, Bernhard, Angewandte Chemie, 2018, 57(22), 6572-6576

Production Method 2

51770-04-8

89324-44-7

Reaction Conditions

1.1 Reagents: Water Solvents: Water

Reference

Synthesis and properties of cyanoformylthiophenes and -selenophenes

Dubus, Pierre; Decroix, Bernard; Morel, Jean; Pastour, Paul, Bulletin de la Societe Chimique de France, 1976, 628, 628-34

5-Formylthiophene-3-carboxylic acid Raw materials

• 5-Formylthiophene-3-carbonitrile
• 2-(4-Bromothien-2-yl)-1,3-dioxolane

5-Formylthiophene-3-carboxylic acid Preparation Products

• 5-Formylthiophene-3-carboxylic acid (89324-44-7)

• 1. An atomically efficient, highly stable and redox active Ce0.5Tb0.5Ox (3% mol.)/MgO catalyst for total oxidation of methane?
  Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
• 2. Acenaphthenic hopanoids, a novel series of aromatised
  Teresita Carrillo-Hernández,Philippe Schaeffer,Pierre Albrecht Chem. Commun., 2001, 1976-1977
• 3. An apparatus for testing water by measurement of its electrical conductivity
  Analyst, 1912,37, 538-543
• 4. An amphoteric reactivity of a mixed-valent bis(μ-oxo)dimanganese(iii,iv) complex acting as an electrophile and a nucleophile?
  Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
• 5. An analysis of the WTC fires using CIB correlations and simple modeling
  JGQuintiere

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Thiophenes Thiophene carboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Thiophenes Thiophene carboxylic acids and derivatives Thiophene carboxylic acids

• 36157-39-8(thiophene-2,4-dicarboxylic acid)
• 67808-66-6(Methyl 5-formylthiophene-3-carboxylate)
• 26421-32-9(2,5-Dimethylthiophene-3-carboxylic acid)
• 4506-94-9(2,3,4,5-Thiophenetetracarboxylicacid)
• 207277-10-9(2-Thiophenecarboxaldehyde, 4-(hydroxymethyl)- (9CI))
• 893737-11-6(3-(5-formylthiophen-3-yl)benzoic acid)
• 19991-69-6(2-Formylthiophene-3-carboxylic acid)
• 19156-50-4(5-Methylthiophene-3-carboxylic acid)
• 54796-48-4(4-(methoxymethyl)thiophene-2-carbaldehyde)
• 57234-00-1(2,2'-Diformyl(3,3'-bithiophene)-4,4'-dicarboxylicacid)