Production Method 1

1681-37-4

89284-05-9

Reaction Conditions

1.1 Reagents: Acetic acid ,  Potassium acetate ;  1 h, 25 °C
1.2 Reagents: Bromine ;  25 °C; 17 h, 25 °C
1.3 Reagents: Water

Reference

Identification of 2,4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and In Vivo Efficacy in the Plasmodium falciparum NSG Mouse Model

Horatscheck, Andre; Andrijevic, Ana; Nchinda, Aloysius T.; Le Manach, Claire ; Paquet, Tanya; et al, Journal of Medicinal Chemistry, 2020, 63(21), 13013-13030

Production Method 2

31872-63-6

89284-05-9

Reaction Conditions

1.1 Reagents: Ammonia Solvents: Water ;  8 h, 100 °C

Reference

Synthesis and characterization of arylamine aromatic aldehyde Schiff base

Cai, Ming-jian; Wu, Shu-xin; Wang, Xiu-ge, Huaxue Shijie, 2013, 54(4), 233-236

Production Method 3

1681-37-4

89284-05-9

Reaction Conditions

1.1 Reagents: Sodium acetate ,  Bromine Solvents: Acetic acid ;  48 h, rt
1.2 Reagents: Sodium thiosulfate Solvents: Water ;  rt

Reference

Efficient synthesis of aminomethylated azaindoles and corresponding pyrrole-fused derivatives by copper-catalyzed domino multicomponent coupling and cyclization

Hou, Zengye; Suzuki, Yamato; Oishi, Shinya; Fujii, Nobutaka; Ohno, Hiroaki, Tetrahedron, 2012, 68(6), 1695-1703

Production Method 4

1681-37-4

89284-05-9

Reaction Conditions

1.1 Reagents: Potassium acetate Solvents: Acetic acid ;  1 h, rt
1.2 Reagents: Bromine ;  rt; overnight, rt
1.3 Reagents: Water

Reference

Preparation of novel 2,3,8-trisubstituted pyrido[3,4-b]pyrazines and pyrido[2,3-b]pyrazines

Antoine, Maud; Czech, Michael; Gerlach, Matthias; Gunther, Eckhard; Schuster, Tilmann; et al, Synthesis, 2011, (5), 794-806

3-bromo-5-nitro-pyridin-4-amine Raw materials

• 3-nitropyridin-4-amine
• 3-bromo-4-chloro-5-nitro-pyridine

3-bromo-5-nitro-pyridin-4-amine Preparation Products

• 3-bromo-5-nitro-pyridin-4-amine (89284-05-9)

• 1. Aggregation, pretransitional behavior, and optical properties in the isotropic phase of lyotropic chromonic liquid crystals studied in high magnetic fields
  Tanya Ostapenko,Peter J. Collings,Samuel N. Sprunt,J. T. Gleeson Soft Matter, 2013,9, 9487-9498
• 2. An Assessment of the Laminar Hypersonic Double-Cone Experiments in the LENS-XX Tunnel
  JaideepRay,PatrickBlonigan,EricT.Phipps,KathrynMaupin
• 3. Aggregation-induced emission enhancement of carbon quantum dots and applications in light emitting devices
  Rongyan Guo,Tao Li,Shuie Shi J. Mater. Chem. C, 2019,7, 5148-5154
• 4. An intermolecular C–H oxidizing strategy to access highly fused carbazole skeletons from simple naphthylamines?
  Christian K. Rank,Alexander W. Jones,Tatjana Wall,Patrick Di Martino-Fumo,Sarah Schr?ck,Markus Gerhards,Frederic W. Patureau Chem. Commun., 2019,55, 13749-13752
• 5. Alt-proteins: A promising future

• Solvents and Organic Chemicals Organic Compounds Organic 1,3-dipolar compounds Allyl-type 1,3-dipolar organic compounds C-nitro compounds
• Solvents and Organic Chemicals Organic Compounds Organic 1,3-dipolar compounds Allyl-type 1,3-dipolar organic compounds Organic nitro compounds C-nitro compounds

• 139366-41-9(7-Quinolinamine, 6-bromo-8-nitro-)
• 607373-24-0(3-Bromo-N-methyl-5-nitropyridin-4-amine)
• 135513-86-9( )
• 15862-30-3(3-Bromo-5-nitropyridine)
• 6945-68-2(5-bromo-3-nitro-pyridin-2-amine)
• 221241-42-5(4-Amino-2,5-dibromo-3-nitropyridine)
• 15862-31-4(3-bromo-5-nitro-pyridin-2-amine)
• 607372-28-1(4-Pyridinamine, 3-bromo-N-cyclopropyl-5-nitro-)
• 84487-15-0(2-bromo-5-nitro-pyridin-4-amine)
• 607371-01-7(3-Bromo-N-ethyl-5-nitropyridin-4-amine)