Production Method 1

158221-58-0

89115-95-7

Reaction Conditions

1.1 Reagents: Hydrogen Catalysts: Palladium dihydroxide Solvents: Methanol ,  Water ;  24 h, 5 bar, rt

Reference

An efficient, asymmetric synthesis of pipecolic acid and 2-alkyl pipecolic acids

Hou, Duen-Ren; Hung, Shin-Yi; Hu, Chung-Cheng, Tetrahedron: Asymmetry, 2005, 16(23), 3858-3864

Production Method 2

89460-63-9

89115-95-7

Reaction Conditions

Reference

Synthesis and resolution of substituted pipecolic acids

Overberger, C. G.; Shalati, M. D., European Polymer Journal, 1983, 19(10-11), 1055-65

Production Method 3

185385-23-3

89115-95-7

Reaction Conditions

1.1 Reagents: Trimethylsilyl iodide Solvents: Chloroform

Reference

New synthetic method of optically active α-methylproline and α-methylpipecolinic acid using electrochemical oxidation as a key reaction

Matsumura, Yoshihiro; Kinoshita, Toshio; Yanagihara, Yuka; Kanemoto, Noriko; Watanabe, Mitsuaki, Tetrahedron Letters, 1996, 37(46), 8395-8398

(2S)-2-methylpiperidine-2-carboxylic acid Raw materials

• 1,2-Piperidinedicarboxylic acid, 2-methyl-, 1-(phenylmethyl) ester, (S)-
• 1,2-Piperidinedicarboxylic acid, 2-methyl-, 1,2-dimethyl ester, (2S)-
• Pyrido[2,1-c][1,4]oxazin-1(6H)-one, hexahydro-9a-methyl-4-phenyl-, (4R,9aS)-

(2S)-2-methylpiperidine-2-carboxylic acid Preparation Products

• (2S)-2-methylpiperidine-2-carboxylic acid (89115-95-7)

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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

• 874368-42-0((2R)-2-ethyl-2-Piperidinecarboxylic acid)
• 123053-15-6(2-Piperidinecarboxylic acid, 2-ethyl-, (2S)-)
• 85819-03-0(piperidine-2,4-dicarboxylic acid)
• 874368-17-9(2-Piperidinecarboxylic acid, 2-propyl-, (2S)-)
• 874368-16-8(2-Piperidinecarboxylic acid, 2-propyl-, (2R)-)
• 1417805-94-7(2-Methyl-2-(2r)-piperidinecarboxylic acid hcl)
• 1227465-64-6(2-Ethylpiperidine-2-carboxylic acid)
• 72518-41-3(2-Methylpiperidine-2-carboxylic acid)
• 123053-16-7(1H-Azepine-2-carboxylicacid, hexahydro-2-methyl-, (S)- (9CI))
• 105141-61-5((2R)-2-methylpiperidine-2-carboxylic acid)