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2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029184315-5g |
6-Chloro-N-methylpyridin-2-amine |
89026-78-8 | 98% | 5g |
$196.20 | 2023-08-31 | |
| Alichem | A029184315-10g |
6-Chloro-N-methylpyridin-2-amine |
89026-78-8 | 98% | 10g |
$301.60 | 2023-08-31 | |
| Alichem | A029184315-25g |
6-Chloro-N-methylpyridin-2-amine |
89026-78-8 | 98% | 25g |
$574.20 | 2023-08-31 | |
| TRC | C350005-100mg |
6-Chloro-N-methylpyridin-2-amine |
89026-78-8 | 100mg |
$ 64.00 | 2023-04-18 | ||
| TRC | C350005-250mg |
6-Chloro-N-methylpyridin-2-amine |
89026-78-8 | 250mg |
$ 75.00 | 2023-04-18 | ||
| TRC | C350005-500mg |
6-Chloro-N-methylpyridin-2-amine |
89026-78-8 | 500mg |
$ 87.00 | 2023-04-18 | ||
| TRC | C350005-1g |
6-Chloro-N-methylpyridin-2-amine |
89026-78-8 | 1g |
$ 98.00 | 2023-04-18 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | C845626-1g |
6-Chloro-N-methylpyridin-2-amine |
89026-78-8 | 98% | 1g |
￥306.90 | 2022-09-02 | |
| Matrix Scientific | 052705-2.500g |
6-Chloro-N-methyl-2-pyridinamine |
89026-78-8 | 2.500g |
$130.00 | 2021-06-27 | ||
| Matrix Scientific | 052705-500mg |
6-Chloro-N-methyl-2-pyridinamine |
89026-78-8 | 500mg |
$40.00 | 2021-06-27 |
Audited Supplier
6-Chloro-N-methylpyridin-2-amine (CAS No. 89026-78-8) is a versatile compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound, also known as 2-(methylamino)-5-chloropyridine, is a derivative of pyridine and features a chlorine atom and a methylamino group attached to the pyridine ring. Its unique chemical structure endows it with a range of biological activities, making it a valuable intermediate in the synthesis of various pharmaceuticals and agrochemicals.
The chemical formula of 6-Chloro-N-methylpyridin-2-amine is C7H8ClN2, and it has a molecular weight of approximately 155.60 g/mol. The compound is typically supplied as a white to off-white solid with a melting point ranging from 43 to 46°C. It is soluble in common organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), which facilitates its use in various chemical reactions and biological assays.
In recent years, 6-Chloro-N-methylpyridin-2-amine has been extensively studied for its potential applications in drug discovery and development. One of the key areas of interest is its role as an intermediate in the synthesis of antiviral agents. For instance, a study published in the Journal of Medicinal Chemistry highlighted the use of this compound in the development of novel inhibitors against viral proteases, which are crucial for the replication of viruses such as HIV and hepatitis C virus (HCV). The researchers demonstrated that derivatives of 6-Chloro-N-methylpyridin-2-amine exhibited potent antiviral activity, making them promising candidates for further clinical evaluation.
Beyond antiviral applications, 6-Chloro-N-methylpyridin-2-amine has also shown potential in the treatment of neurological disorders. A study conducted by researchers at the University of California, San Francisco, investigated the neuroprotective effects of this compound in models of Parkinson's disease. The results indicated that 6-Chloro-N-methylpyridin-2-amine-derived compounds could effectively reduce oxidative stress and neuroinflammation, thereby protecting dopaminergic neurons from degeneration. These findings suggest that this compound may have therapeutic potential in neurodegenerative diseases.
The versatility of 6-Chloro-N-methylpyridin-2-amine extends to its use in the development of anti-inflammatory agents. A recent study published in the Bioorganic & Medicinal Chemistry Letters reported that derivatives of this compound exhibited significant anti-inflammatory activity by inhibiting the production of pro-inflammatory cytokines such as TNF-α and IL-1β. The researchers noted that these compounds could be developed into novel therapeutic agents for conditions such as rheumatoid arthritis and inflammatory bowel disease.
In addition to its biological activities, 6-Chloro-N-methylpyridin-2-amine has also been explored for its utility as a building block in organic synthesis. Its reactivity and functional group compatibility make it an attractive starting material for the synthesis of complex molecules with diverse biological activities. For example, a study published in the Tetrahedron Letters described a novel synthetic route to access a series of substituted pyridines using 6-Chloro-N-methylpyridin-2-amine. The method involved palladium-catalyzed cross-coupling reactions, which allowed for efficient and scalable synthesis of target compounds with high purity and yield.
The safety profile of 6-Chloro-N-methylpyridin-2-amine is another important consideration for its use in pharmaceutical research. Preclinical studies have generally shown that this compound is well-tolerated at therapeutic doses, with minimal toxicity observed in animal models. However, as with any chemical compound used in drug development, thorough safety assessments are essential to ensure its safe use in humans.
In conclusion, 6-Chloro-N-methylpyridin-2-amine (CAS No. 89026-78-8) is a multifaceted compound with a wide range of applications in medicinal chemistry and pharmaceutical research. Its unique chemical structure and diverse biological activities make it an invaluable intermediate in the synthesis of novel drugs targeting various diseases. Ongoing research continues to uncover new possibilities for this compound, further solidifying its importance in the field.
