Production Method 1

89007-61-4

Reaction Conditions

1.1 Catalysts: Hydrazine, phenyl- ,  Copper, [α,α-bis[2-butoxy-5-(1,1-dimethylethyl)phenyl]-β-[[(2-hydroxyphenyl)meth… Solvents: Dichloromethane ;  rt → 40 °C; 5 min, 40 °C
1.2 Solvents: Dichloromethane ;  40 °C; overnight, 40 °C

Reference

Catalytic asymmetric synthesis of (S)-2,2-dimethylcyclopropanecarboxamide

Chen, Rui-ye; Wang, Qi-jun; Ouyang, Luo; Xu, Dong-cheng; Li, Xin-sheng, Huaxue Shiji, 2011, 33(6), 570-572

Production Method 2

89007-61-4

Reaction Conditions

1.1 Catalysts: Copper(I) triflate ,  2,2-Bis(4(R)-tert-butyl-1,3-oxazolin-2-yl)propane Solvents: Chloroform ;  0 °C

Reference

Copper(I) trifluoromethanesulfonate

Salomon, Robert G.; Dauban, Philippe; Dodd, Robert H., e-EROS Encyclopedia of Reagents for Organic Synthesis, 2005, 1, 1-23

Production Method 3

89007-61-4

Reaction Conditions

1.1 Reagents: Hydrazine, phenyl- Catalysts: (SP-4-2)-[(4S)-4-(1,1-Dimethylethyl)-N-[(4S)-4-(1,1-dimethylethyl)-4,5-dihydro-2… (siliceous mesocellular foam-supported) Solvents: Dichloromethane ;  rt
1.2 Solvents: Dichloromethane ;  2 h, 10 °C; 1 h, 10 °C → rt

Reference

Siliceous mesocellular foam-supported aza(bisoxazoline)-copper catalysts

Lim, Jaehong; Riduan, Siti Nurhanna; Lee, Su Seong; Ying, Jackie Y., Advanced Synthesis & Catalysis, 2008, 350(9), 1295-1308

Production Method 4

89007-61-4

Reaction Conditions

1.1 Catalysts: Copper(II) triflate Solvents: Dichloromethane ;  5 h, 0 °C; 14 h, 0 °C → rt

Reference

Improved enantioselectivity of immobilized chiral bisoxazolines by partial precapping of the siliceous mesocellular foam support with trimethylsilyl groups

Lee, Su Seong; Hadinoto, Sukandar; Ying, Jackie Y., Advanced Synthesis & Catalysis, 2006, 348, 1248-1254

Production Method 5

89007-61-4

Reaction Conditions

1.1 Catalysts: Copper(I) triflate ,  2,2-Bis(4(R)-tert-butyl-1,3-oxazolin-2-yl)propane Solvents: Chloroform ;  1 h, rt
1.2 Solvents: Chloroform ;  0 °C
1.3 Solvents: Chloroform ;  0 °C; 14 h, 0 °C → rt

Reference

Synthesis of (S)-(+)-2,2-dimethylcyclopropanecarboxamide

Wu, Likun; Zhang, Fuli, Zhongguo Yiyao Gongye Zazhi, 2011, 42(7), 491-494

Production Method 6

89007-61-4

Reaction Conditions

1.1 Catalysts: [(4S,4′S)-2,2′-(1-Methylethylidene)bis[4-(1,1-dimethylethyl)-4,5-dihydrooxazole-… ;  rt

Reference

2,2-Bis[2-[4(S)-tert-butyl-1,3-oxazolinyl]]propane

Magnus, Angelika S.; Andersson, Pher G., e-EROS Encyclopedia of Reagents for Organic Synthesis, 2003, 1, 1-7

Production Method 7

89007-61-4

Reaction Conditions

1.1 Reagents: Copper(I) triflate ,  2,2-Bis(4(R)-tert-butyl-1,3-oxazolin-2-yl)propane Solvents: Chloroform ;  0 °C

Reference

Copper(I) Trifluoromethanesulfonate

Salomon, Robert G.; Dauban, Philippe; Dodd, Robert H., e-EROS Encyclopedia of Reagents for Organic Synthesis, 2001, ,

Cyclopropanecarboxylic acid, 2,2-dimethyl-, ethyl ester, (S)- Preparation Products

• Cyclopropanecarboxylic acid, 2,2-dimethyl-, ethyl ester, (S)- (89007-61-4)

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• 4. Excimer formation effects and trap-assisted charge recombination loss channels in organic solar cells of perylene diimide dimer acceptors?
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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Cyclopropanecarboxylic acids and derivatives

• 39255-32-8(Ethyl 2-methylpentanoate)
• 10032-15-2(Hexyl 2-methylbutanoate)
• 10138-59-7(1,2-Cyclohexanedicarboxylic Acid Diethyl Ester)
• 2938-48-9(2,2-Dimethylglutaric anhydride)
• 67911-21-1(6,6-Dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione)
• 25550-51-0(Methylhexahydroisobenzofuran-1,3-Dione)
• 2094-73-7(1-Adamantylcarboxylic Acid Ethyl Ester)
• 18268-70-7(3,6,9-Trioxaundecamethylenebis-(2-ethylhexanoate))
• 14924-53-9(Ethyl cyclobutanecarboxylate)
• 94-28-0(Tri(ethylenglycol)bis-2-ethylhexanoate)