Production Method 1

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Tin(2+), [5,10,15,20-tetraphenyl-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]-, (… Solvents: Acetonitrile ;  5 min, rt

Reference

Highly efficient and selective acetylation of alcohols and phenols with acetic anhydride catalyzed by a high-valent tin(IV) porphyrin, Sn(TPP)(BF4)2

Moghadam, Majid; Tangestaninejad, Shahram; Mirkhani, Valiollah; Mohammadpoor-Baltork, Iraj; Taghavi, S. Abdolmanaf, Journal of Molecular Catalysis A: Chemical, 2007, 274(1-2), 217-223

Production Method 2

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Lithium perchlorate

Reference

Lithium perchlorate catalyzed acetylation of alcohols under mild reaction conditions

Nakae, Yasuyuki; Kusaki, Ikuko; Sato, Tsuneo, Synlett, 2001, (10), 1584-1586

Production Method 3

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Scandium triflate Solvents: Acetonitrile

Reference

Method for producing esters

, Japan, , ,

Production Method 4

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Antimony trichloride ;  6 min, rt

Reference

SbCl3 as a highly efficient catalyst for the acetylation of alcohols, phenols, and amines under solvent-free conditions

Bhattacharya, Asish K.; Diallo, Mamadou A.; Ganesh, Krishna N., Synthetic Communications, 2008, 38(10), 1518-1526

Production Method 5

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Ceria ,  Yttrium sesquioxide Solvents: Acetonitrile ;  4 h, reflux

Reference

Synthesis of a ceria-yttria based strong Lewis acid heterogeneous catalyst: application to chemoselective acylation and ene reactions

Pandey, Rajesh K.; Dagade, Sharda P.; Malase, Kusum M.; Songire, Sachin B.; Kumar, Pradeep, Journal of Molecular Catalysis A: Chemical, 2006, 245(1-2), 255-259

Production Method 6

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Manganese(salen) chloride Solvents: Toluene

Reference

Mn(III) salen complex: an efficient reusable acylation catalyst

Choudary, B. M.; Kantam, M. L.; Bharathi, B.; Venkat Reddy, C. R., Journal of Molecular Catalysis A: Chemical, 2001, 168(1-2), 69-73

Production Method 7

89-78-1

89-48-5

Reaction Conditions

1.1 Reagents: Diisopropylethylamine Catalysts: 4-(Dimethylamino)pyridine Solvents: Acetonitrile ;  0.5 h, rt

Reference

Rational Design of an L-Histidine-Derived Minimal Artificial Acylase for the Kinetic Resolution of Racemic Alcohols

Ishihara, Kazuaki; Kosugi, Yuji; Akakura, Matsujiro, Journal of the American Chemical Society, 2004, 126(39), 12212-12213

Production Method 8

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: (OC-6-11)-Tris[1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl-κO]methanesulfonamid… Solvents: Acetonitrile

Reference

A new scandium complex as an extremely active acylation catalyst

Ishihara, Kazuaki; Kubota, Manabu; Yamamoto, Hisashi, Synlett, 1996, (3), 265-6

Production Method 9

108-22-5

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: p-Toluenesulfonic acid Solvents: Acetonitrile ;  17 h, rt

Reference

Isopropenyl acetate: A cheap and general acylating agent of alcohols under metal-free conditions

Temperini, Andrea; Minuti, Lucio; Morini, Tommaso; Rosati, Ornelio; Piazzolla, Francesca, Tetrahedron Letters, 2017, 58(43), 4051-4053

Production Method 10

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Neodymium nitrate hexahydrate ;  6 h, 405 K

Reference

Preparation of SO42-/Fe2O3-TiO2-Nd2O3 solid acid and its activity for the synthesis of menthyl acetate

Yang, Chunhua; Fan, Meiqing; Chen, Gang; Zhang, Long, Journal of the Chemical Society of Pakistan, 2012, 34(1), 72-75

Production Method 11

89-78-1

89-48-5

Reaction Conditions

1.1 Solvents: Water ;  9.9 s, 5 MPa, 200 °C

Reference

A highly selective, high-speed, and hydrolysis-free O-acylation in subcritical water in the absence of a catalyst

Sato, Masahiro; Matsushima, Keiichiro; Kawanami, Hajime; Ikuhsima, Yutaka, Angewandte Chemie, 2007, 46(33), 6284-6288

Production Method 12

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Tin(2+), tetraaquadibutyl-, (OC-6-11)-, 1,5-naphthalenedisulfonate (1:1) ;  15 min, rt

Reference

Synthesis, structure and reactivity of Hydrated and dehydrated organotin cations

Chandrasekhar, Vadapalli; Boomishankar, Ramamoorthy; Gopal, Kandasamy; Sasikumar, Palani; Singh, Puja; et al, European Journal of Inorganic Chemistry, 2006, (20), 4129-4136

Production Method 13

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Molybdenum chloride oxide (MoCl2O2), (T-4)- Solvents: Dichloromethane ;  rt; 30 min, rt
1.2 6 h, rt
1.3 Reagents: Water ;  cooled

Reference

Nucleophilic acyl substitutions of anhydrides with protic nucleophiles catalyzed by amphoteric, oxomolybdenum species

Chen, Chien-Tien; Kuo, Jen-Huang; Pawar, Vijay D.; Munot, Yogesh S.; Weng, Shieu-Shien; et al, Journal of Organic Chemistry, 2005, 70(4), 1188-1197

Production Method 14

89-78-1

89-48-5

Reaction Conditions

1.1 Solvents: Acetic acid

Reference

Liquid phase acylation of alcohols with acetic acid over zeolites

Narender, N.; Srinivasu, P.; Kulkarni, S. J.; Raghavan, K. V., Synthetic Communications, 2000, 30(11), 1887-1893

Production Method 15

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: 2,8,9-Trimethyl-2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane Solvents: Tetrahydrofuran
1.2 -

Reference

P(RNCH2CH2)3N: Efficient catalysts for transesterifications, acylations, and deacylations

Ilankumaran, Palanichamy; Verkade, J. G., Journal of Organic Chemistry, 1999, 64(9), 3086-3089

Production Method 16

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: 2,8,9-Trimethyl-2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane Solvents: Pentane

Reference

Superbase-Promoted Acylation of Hindered Alcohols

D'Sa, Bosco A.; Verkade, John G., Journal of Organic Chemistry, 1996, 61(9), 2963-6

Production Method 17

89-78-1

89-48-5

Reaction Conditions

1.1 Reagents: Triethylamine Catalysts: 1-Methylimidazole Solvents: Dichloromethane ;  3 h, rt

Reference

Practical and efficient acylation and tosylation of sterically hindered alcohols catalyzed with 1-methylimidazole

Wu, Qin-pei; Liu, Hua; Liu, Hai-xia; Chen, Xi; Wang, Hao; et al, Chemical Research in Chinese Universities, 2010, 26(1), 55-59

Production Method 18

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Zinc acetate ;  4 h, rt
1.2 Reagents: Sodium bicarbonate Solvents: Water ;  1 h, rt

Reference

Acetylation of hydroxy radical catalyzed by Zn(AcO)2 using acetic anhydride as solvent

Xu, Shao-hong; Yao, Peng, Huaxue Shiji, 2009, 31(9), 761-763

Production Method 19

89-78-1

89-48-5

Reaction Conditions

1.1 Catalysts: Copper(II) tetrafluoroborate ;  30 min, rt

Reference

Copper(II) tetrafluoroborate-catalyzed acetylation of phenols, thiols, alcohols, and amines

Chakraborti, Asit K.; Gulhane, Rajesh; Shivani, Synthesis, 2004, (1), 111-115

(±)-Menthyl Acetate Raw materials

• Isopropenyl acetate
• DL-Menthol

(±)-Menthyl Acetate Preparation Products

• (±)-Menthyl Acetate (89-48-5)

• 1. Dissociation of aryl sulfonyl phthalimide radical anions: relevance to the biological activity of arylsulfonyl amides?
  Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
• 2. Excimer–monomer switch: a reaction-based approach for selective detection of fluoride?
  Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
• 3. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 4. Fc microparticles can modulate the physical extent and magnitude of complement activity?
  David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
• 5. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212

• Solvents and Organic Chemicals Organic Compounds Acids/Esters

• 51446-59-4(Cyclohexanol,2-methyl-5-(1-methylethyl)-, 1-acetate, (1S,2S,5S)-)
• 5256-66-6(Cyclohexanol,2-methyl-5-(1-methylethyl)-, 1-acetate, (1R,2R,5R)-rel-)
• 2230-87-7(Neomenthyl Acetate)
• 54714-34-0(Cyclohexanol, 2-methyl-, acetate, trans-)
• 34362-41-9(Cyclohexanepropanol, a,b-dimethyl-, 1-acetate)
• 51546-61-3(Cyclohexanol,2-methyl-5-(1-methylethyl)-, 1-acetate, (1S,2R,5S)-)
• 2552-91-2((+)-Neomenthyl Acetate)
• 2114-32-1(Cyclohexanemethanol, a-ethyl-, 1-acetate)
• 27428-32-6(Cyclohexanemethanol, a-cyclohexyl-, acetate (9CI))
• 51446-60-7(Cyclohexanol,2-methyl-5-(1-methylethyl)-, 1-acetate, (1S,2S,5R)-)