Production Method 1

1118786-87-0

889944-57-4

Reaction Conditions

1.1 Reagents: Sodium hydroxide
1.2 Reagents: Pyridine ;  heated

Reference

Cyclobutane-Derived Diamines: Synthesis and Molecular Structure

Radchenko, Dmytro S.; Pavlenko, Sergiy O.; Grygorenko, Oleksandr O.; Volochnyuk, Dmitriy M.; Shishkina, Svitlana V.; et al, Journal of Organic Chemistry, 2010, 75(17), 5941-5952

Production Method 2

1023814-92-7

889944-57-4

Reaction Conditions

1.1 Solvents: Pyridine ;  5 h, reflux
1.2 Reagents: Hydrochloric acid Solvents: Water ;  rt

Reference

Synthesis of conformationally restricted glutamic acid analogs based on the spiro[3.3]heptane scaffold

Radchenko, Dmytro S.; Grygorenko, Oleksandr O.; Komarov, Igor V., Tetrahedron: Asymmetry, 2008, 19(24), 2924-2930

6-Oxospiro[3.3]heptane-2-carboxylic acid Raw materials

• 2,2-bis(propan-2-yl) 6,6-dimethoxyspiro[3.3]heptane-2,2-dicarboxylate
• 6-Oxospiro[3.3]heptane-2,2-dicarboxylic acid

6-Oxospiro[3.3]heptane-2-carboxylic acid Preparation Products

• 6-Oxospiro[3.3]heptane-2-carboxylic acid (889944-57-4)

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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

• 766513-48-8(3-oxo-1-(propan-2-yl)cyclobutane-1-carboxylic acid)
• 473-68-7(3-acetyl-2,2-dimethylcyclobutane-1-carboxylic acid)
• 156329-75-8(3-acetylbicyclo[1.1.1]pentane-1-carboxylic acid)
• 113522-54-6(Cyclobutanecarboxylicacid, 2-acetyl-1-methyl-, (1R,2S)-rel-)
• 3183-43-5(2,2-dimethyl-3-oxocyclobutane-1-carboxylic acid)
• 286442-89-5(1-methyl-3-oxocyclobutane-1-carboxylic Acid)
• 28587-41-9(rac-(1R,3S)-3-acetyl-2,2-dimethylcyclobutane-1-carboxylic acid)
• 288848-24-8((1S,3R)-3-acetyl-2,2-dimethyl-cyclobutanecarboxylic acid)
• 22571-78-4((1R,3S)-3-acetyl-2,2-dimethylcyclobutane-1-carboxylic acid)
• 279240-50-5(Cyclobutanecarboxylic acid, 3-acetyl-2,2-dimethyl-, (1s,3s)-(9ci))