Production Method 1

26218-78-0

889676-37-3

Reaction Conditions

1.1 Reagents: Borate(1-), amidotrihydro-, sodium, (T-4)- Solvents: Tetrahydrofuran ;  5 min, rt
1.2 Solvents: Water ;  15 min, rt

Reference

Efficient synthesis of primary and secondary amides via reacting esters with alkali metal amidoboranes

Guo, Yu ; Wang, Ruo-Ya; Kang, Jia-Xin ; Ma, Yan-Na; Xu, Cong-Qiao ; et al, Nature Communications, 2021, 12(1),

Production Method 2

6311-35-9

889676-37-3

Reaction Conditions

1.1 Reagents: Ammonium hydroxide ,  Diisopropylethylamine ,  O-(7-Azabenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate Solvents: Dimethylformamide ,  Water ;  1 h, rt

Reference

Structure-Guided Modification of Heterocyclic Antagonists of the P2Y14 Receptor

Yu, Jinha; Ciancetta, Antonella ; Dudas, Steven; Duca, Sierra; Lottermoser, Justine; et al, Journal of Medicinal Chemistry, 2018, 61(11), 4860-4882

Production Method 3

6311-35-9

889676-37-3

Reaction Conditions

1.1 Reagents: 1,1′-Carbonyldiimidazole Solvents: Tetrahydrofuran ;  3 h, rt
1.2 Reagents: Ammonium hydroxide Solvents: Water ;  rt; overnight, rt

Reference

Design, synthesis and biological evaluation of indole derivatives as Vif inhibitors

Pu, Chunlan; Luo, Rong-Hua; Zhang, Mengqi; Hou, Xueyan; Yan, Guoyi; et al, Bioorganic & Medicinal Chemistry Letters, 2017, 27(17), 4150-4155

6-bromopyridine-3-carboxamide Raw materials

• methyl 6-bromopyridine-3-carboxylate
• 6-bromopyridine-3-carboxylic acid

6-bromopyridine-3-carboxamide Preparation Products

• 6-bromopyridine-3-carboxamide (889676-37-3)

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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxamides
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Pyridinecarboxamides

• 1260790-20-2(2,6-Dibromonicotinohydrazide)
• 869640-49-3(6-Bromo-N,N-dimethylnicotinamide)
• 951885-70-4(6-Bromo-N-ethylnicotinamide)
• 87674-18-8(2-bromopyridine-3-carboxamide)
• 869640-48-2(6-bromo-N-methyl-pyridine-3-carboxamide)
• 2464-63-3(2,6-dibromo-4-amidopyridine)
• 1379303-54-4(2,6-Dibromopyridine-3-carboxamide)
• 149806-06-4(6-Bromopyridine-3-carboxaldehyde)
• 1114563-25-5(6-bromo-N-cyclopropyl-3-pyridinecarboxamide)
• 29840-73-1(2-bromopyridine-4-carboxamide)