Production Method 1

69961-11-1

889670-02-4

Reaction Conditions

1.1 Reagents: Sodium iodide Solvents: Acetone ;  12 - 18 h, reflux

Reference

Synthesis of highly substituted pyrrolidines via double Michael addition reaction and its anti-microbial activity

Chandan, Nandkishor, American Journal of PharmTech Research, 2016, 6(5), 640-647

Production Method 2

69942-12-7

889670-02-4

Reaction Conditions

1.1 Reagents: Imidazole ,  Triphenylphosphine Solvents: Dichloromethane ;  10 min, rt; rt → 0 °C
1.2 Reagents: Iodine ;  40 min, 0 °C; 0 °C → rt; 10 min, rt; rt → 0 °C
1.3 Solvents: Dichloromethane ;  10 min, 0 °C; 1 h, 0 °C; 0 °C → rt; 1.5 h, rt

Reference

Nickel-catalyzed cross-coupling of amino-acid-derived alkylzinc reagents with alkyl bromides/chlorides: Access to diverse unnatural amino acids

Gou, Fei-Hu; Ma, Ming-Jian; Wang, An-Jun; Zhao, Liang; Wang, Haoyang ; et al, Organic Letters, 2022, 24(1), 240-244

Methyl 2-(tert-Butoxycarbonylamino)-3-iodopropanoate Raw materials

• Serine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester, 4-methylbenzenesulfonate (ester) (9CI)
• N-BOC-DL-serine methyl ester

Methyl 2-(tert-Butoxycarbonylamino)-3-iodopropanoate Preparation Products

• Methyl 2-(tert-Butoxycarbonylamino)-3-iodopropanoate (889670-02-4)

• 1. Evolution and characterization of a benzylguanine-binding RNA aptamer?
  J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
• 2. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 3. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita
• 4. Evolution of dealloying induced strain in nanoporous gold crystals?
  Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
• 5. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
  Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)