Production Method 1

2585-28-6

888-79-9

Reaction Conditions

1.1 Reagents: Iron ,  Ammonium chloride Solvents: Ethanol ,  Water ;  3 h, 80 °C

Reference

Synthesis and biological evaluation of 2,4-disubstituted phthalazinones as Aurora kinase inhibitors

Wang, Wei; Feng, Xiu; Liu, Huan-Xiang; Chen, Shi-Wu; Hui, Ling, Bioorganic & Medicinal Chemistry, 2018, 26(12), 3217-3226

Production Method 2

16106-38-0

888-79-9

Reaction Conditions

Reference

A comparative study of the catalytic activity of Co- and CoFe2O4-NPs in C-N and C-O bond formation: synthesis of benzimidazoles and benzoxazoles from o-haloanilides

Hajipour, Abdol R.; Khorsandi, Zahra, New Journal of Chemistry, 2016, 40(12), 10474-10481

Production Method 3

2585-28-6

888-79-9

Reaction Conditions

1.1 Reagents: Stannous chloride Solvents: Ethanol ;  3 h, reflux

Reference

Synthesis and in vitro antiproliferative activity of novel pyrazolo[3,4-d]pyrimidine derivatives

Abdou, Nermin S.; Serya, Rabah A. T.; Esmat, Ahmed; Tolba, Mai F.; Ismail, Nasser S. M.; et al, MedChemComm, 2015, 6(8), 1518-1534

Production Method 4

2585-28-6

888-79-9

Reaction Conditions

1.1 Reagents: Iron ,  Ammonium chloride Solvents: Methanol ,  Water ;  2 - 6 h, 70 °C
1.2 Reagents: Sodium hydroxide Solvents: Water ;  pH 8 - 10

Reference

Discovery of benzamide derivatives containing urea moiety as soluble epoxide hydrolase inhibitors

Tian, Ye; Li, Shuo; Dong, Kuan; Su, Xiaolu; Fu, Siyu; et al, Bioorganic Chemistry, 2022, 127,

Production Method 5

60498-39-7

888-79-9

Reaction Conditions

1.1 Reagents: Thionyl chloride Solvents: Benzene ;  3 h, reflux
1.2 3 h, reflux

Reference

Design and synthesis and biological evaluation of antibacterial agents

Dhoke, Manoj V.; Preethishree, C.; Verma, Usha; Sowmya, B. A., World Journal of Pharmaceutical Research, 2020, 9(5), 933-953

Production Method 6

888-79-9

Reaction Conditions

1.1 Reagents: Trifluoroacetic acid Solvents: Dichloromethane ;  1 h, rt

Reference

Synthesis and identification of 2,4-bisanilinopyrimidines bearing 2,2,6,6-tetramethylpiperidine-N-oxyl as potential Aurora A inhibitors

Sang, Chun-Yan; Qin, Wen-Wen; Zhang, Xiu-Juan; Xu, Yu; Ma, You-Zhen; et al, Bioorganic & Medicinal Chemistry, 2019, 27(1), 65-78

4-Amino-N-(2-chlorophenyl)benzamide Raw materials

• 2-{(4-Aminophenyl)carbonylamino}benzoic Acid
• 4-Aminobenzoyl chloride
• Benzamide,N-(2-chlorophenyl)-4-nitro-

4-Amino-N-(2-chlorophenyl)benzamide Preparation Products

• 4-Amino-N-(2-chlorophenyl)benzamide (888-79-9)

• 1. Distinction of trans–cis photoisomers with comparable optical properties in multiple-state photochromic systems – examining a molecule with three azobenzenes via in situ irradiation NMR spectroscopy?
  Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509
• 2. Dissolved oxygen sensor based on fluorescence quenching of oxygen-sensitive ruthenium complexes immobilized in sol–gel-derived porous silica coatings
  Analyst, 1996,121, 785-788
• 3. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
• 4. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?
  Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
• 5. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Anilides Aromatic anilides

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)