Cas no 887974-21-2 ((5-(4-Methoxyphenyl)pyridin-3-yl)methanol)

(5-(4-Methoxyphenyl)pyridin-3-yl)methanol is a versatile aromatic alcohol derivative featuring a pyridine core substituted with a 4-methoxyphenyl group and a hydroxymethyl functional group. This compound is of interest in pharmaceutical and materials research due to its structural motif, which enables further derivatization for drug discovery and functional material synthesis. The presence of both electron-donating methoxy and polar hydroxyl groups enhances its solubility in organic solvents, facilitating downstream reactions. Its well-defined molecular structure makes it a valuable intermediate in the development of bioactive compounds, particularly in kinase inhibitor and heterocyclic chemistry applications. The compound's stability under standard conditions ensures reliable handling and storage.
(5-(4-Methoxyphenyl)pyridin-3-yl)methanol structure
887974-21-2 structure
Product Name:(5-(4-Methoxyphenyl)pyridin-3-yl)methanol
CAS No:887974-21-2
MF:C13H13NO2
MW:215.247823476791
MDL:MFCD06410316
CID:1036559
PubChem ID:24729873
Update Time:2025-05-21

(5-(4-Methoxyphenyl)pyridin-3-yl)methanol Chemical and Physical Properties

Names and Identifiers

    • (5-(4-Methoxyphenyl)pyridin-3-yl)methanol
    • [5-(4-METHOXYPHENYL)-3-PYRIDYL]METHANOL
    • [5-(4-methoxyphenyl)pyridin-3-yl]methanol
    • 5-(4-methoxyphenyl)-3-Pyridinemethanol
    • SY014586
    • AKOS016000635
    • FT-0717006
    • CS-0362984
    • A861441
    • AC7609
    • DTXSID701285092
    • SCHEMBL16675835
    • J-501507
    • MFCD06410316
    • 887974-21-2
    • DB-023560
    • MDL: MFCD06410316
    • Inchi: 1S/C13H13NO2/c1-16-13-4-2-11(3-5-13)12-6-10(9-15)7-14-8-12/h2-8,15H,9H2,1H3
    • InChI Key: KAZWQVHNKWXKGK-UHFFFAOYSA-N
    • SMILES: O(C)C1C=CC(=CC=1)C1C=NC=C(CO)C=1

Computed Properties

  • Exact Mass: 215.094628657g/mol
  • Monoisotopic Mass: 215.094628657g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 3
  • Complexity: 202
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.6
  • Topological Polar Surface Area: 42.4?2

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Additional information on (5-(4-Methoxyphenyl)pyridin-3-yl)methanol

Introducing (5-(4-Methoxyphenyl)pyridin-3-yl)methanol (CAS No. 887974-21-2): A Compound with Promising Applications in Modern Medicinal Chemistry

CAS No. 887974-21-2 refers to a specialized organic compound known as (5-(4-Methoxyphenyl)pyridin-3-yl)methanol. This compound belongs to the class of heterocyclic alcohols, characterized by its pyridine core substituted with a methoxyphenyl group at the 5-position and a hydroxymethyl group at the 3-position. The unique structural features of this molecule make it a subject of significant interest in the field of medicinal chemistry, particularly for its potential applications in drug discovery and development.

The (5-(4-Methoxyphenyl)pyridin-3-yl)methanol structure combines the pharmacophoric properties of pyridine and phenolic moieties, which are well-documented for their role in modulating biological pathways. Pyridine derivatives are widely recognized for their versatility in pharmaceutical applications, often serving as key scaffolds in the design of small-molecule drugs. The methoxyphenyl group introduces additional electronic and steric effects, enhancing the compound's potential for selective interactions with biological targets.

In recent years, there has been a growing emphasis on the development of novel compounds that can address unmet medical needs. The (5-(4-Methoxyphenyl)pyridin-3-yl)methanol (CAS No. 887974-21-2) has emerged as a compound of interest due to its structural complexity and potential biological activity. Its molecular framework suggests that it may exhibit properties such as receptor binding affinity, enzyme inhibition, or modulation of signaling pathways, making it a valuable candidate for further investigation.

One of the most compelling aspects of this compound is its potential in the realm of neurological disorders. Pyridine-based compounds have shown promise in treating conditions such as Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders by interacting with specific neurotransmitter receptors or enzymes. The presence of the methoxyphenyl group may further enhance its ability to cross the blood-brain barrier, a critical factor for therapeutic efficacy in neurological conditions.

Additionally, the (5-(4-Methoxyphenyl)pyridin-3-yl)methanol (CAS No. 887974-21-2) has garnered attention for its potential applications in cancer research. Emerging studies indicate that pyridine derivatives can exhibit anti-cancer properties by inhibiting key enzymes involved in tumor growth and proliferation. The hydroxymethyl group at the 3-position may serve as a site for further functionalization, allowing chemists to design analogs with enhanced potency and selectivity against cancer cell lines.

The compound's structural motif also suggests potential utility in anti-inflammatory therapies. Phenolic compounds are known for their anti-inflammatory effects, often mediated through interactions with cyclooxygenase (COX) enzymes or peroxisome proliferator-activated receptors (PPARs). By incorporating these elements into a single molecular framework, (5-(4-Methoxyphenyl)pyridin-3-yl)methanol may offer a dual-action approach to modulating inflammatory responses.

From a synthetic chemistry perspective, (5-(4-Methoxyphenyl)pyridin-3-yl)methanol represents an interesting challenge due to its complex structure. The synthesis involves multiple steps, including functional group transformations and regioselective substitutions, which require careful optimization to achieve high yields and purity. Advances in synthetic methodologies have enabled more efficient routes to such compounds, facilitating their exploration in medicinal chemistry.

The pharmacological evaluation of (5-(4-Methoxyphenyl)pyridin-3-yl)methanol (CAS No. 887974-21-2) is currently underway in several research laboratories. Initial studies have focused on assessing its interaction with target proteins and evaluating its pharmacokinetic properties. These investigations are crucial for understanding how the compound behaves within biological systems and for identifying potential therapeutic windows.

In conclusion, (5-(4-Methoxyphenyl)pyridin-3-yl)methanol represents a promising candidate for further exploration in medicinal chemistry. Its unique structural features and potential biological activities make it an attractive molecule for drug discovery efforts aimed at treating neurological disorders, cancer, and inflammation. As research continues to uncover new applications for this compound, it is likely to play an increasingly important role in the development of next-generation therapeutics.

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