Production Method 1

24065-33-6

88777-57-5

Reaction Conditions

1.1 Reagents: Thionyl chloride Catalysts: Dimethylformamide ;  3 h, reflux; reflux → rt
1.2 Solvents: Diethyl ether ,  Water ;  0 °C; 1 h, 0 °C

Reference

Catalyst-controlled regiodivergent C-H borylation of multifunctionalized heteroarenes by using iridium complexes

Sasaki, Ikuo; Taguchi, Jumpei; Hiraki, Shotaro; Ito, Hajime; Ishiyama, Tatsuo, Chemistry - A European Journal, 2015, 21(25), 9236-9241

Production Method 2

24065-33-6

506-59-2

88777-57-5

Reaction Conditions

1.1 Reagents: Thionyl chloride Catalysts: Dimethylformamide Solvents: Toluene ;  rt; 2 h, rt → reflux
1.2 Reagents: Sodium hydroxide Solvents: Dichloromethane ,  Water ;  25 °C; 1 h, 25 °C

Reference

Preparation and structural confirmation of the related substances of rivaroxaban

Cai, Zhengyan; Wen, Yingling; Zhang, Xuli; Liu, Zhenren; Hao, Qun, Zhongguo Yiyao Gongye Zazhi, 2014, 45(4), 303-307

2-Thiophenecarboxamide, 5-chloro-N,N-dimethyl- Raw materials

• 5-chlorothiophene-2-carboxylic acid
• Dimethylamine hydrochloride

2-Thiophenecarboxamide, 5-chloro-N,N-dimethyl- Preparation Products

• 2-Thiophenecarboxamide, 5-chloro-N,N-dimethyl- (88777-57-5)

• 1. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 2. Emerging investigator series: bacteriophages as nano engineering tools for quality monitoring and pathogen detection in water and wastewater
  Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
• 3. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 4. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
  Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
• 5. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Thiophenes Thiophene carboxylic acids and derivatives Thiophene carboxamides

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)