• 1. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imaging
  Ghazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
• 2. Exchangeability of amino acid residues with similar physicochemical properties in coiled-coil interactions?
  Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
• 3. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 4. Emerging investigators
  Polym. Chem., 2015,6, 5501-5502
• 5. Evolving better nanoparticles: Genetic algorithms for optimising cluster geometries
  Dalton Trans., 2003, 4193-4207

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Phenylpyrazoles
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Pyrazoles Phenylpyrazoles

Comprehensive Overview of 1-Methyl-3-(3-nitro-phenyl)-1H-pyrazole (CAS No. 886851-64-5)

The compound 1-Methyl-3-(3-nitro-phenyl)-1H-pyrazole (CAS No. 886851-64-5) is a specialized organic molecule that has garnered significant attention in the fields of medicinal chemistry, material science, and agrochemical research. With its unique structural features, this compound serves as a versatile intermediate in the synthesis of more complex molecules. Its pyrazole core, combined with a nitro-phenyl substituent, makes it a valuable building block for designing compounds with potential biological activity. Researchers are increasingly exploring its applications in drug discovery, particularly in targeting enzymes and receptors involved in inflammatory and metabolic disorders.

One of the most searched questions related to 1-Methyl-3-(3-nitro-phenyl)-1H-pyrazole is its role in heterocyclic chemistry. Heterocycles like pyrazoles are pivotal in modern pharmaceuticals due to their ability to mimic natural substrates and interact with biological targets. The presence of the nitro group in this compound further enhances its reactivity, enabling diverse chemical transformations. This aligns with the growing interest in nitro-aromatics as key intermediates in organic synthesis. Recent trends in green chemistry have also spurred investigations into eco-friendly methods for synthesizing such compounds, reducing hazardous byproducts.

Another hot topic tied to CAS No. 886851-64-5 is its potential in material science. The nitro-phenyl moiety can contribute to the development of advanced polymers and coatings with improved thermal stability and optical properties. Searches for "nitro-phenyl pyrazole applications" have surged, reflecting the demand for innovative materials in electronics and nanotechnology. Additionally, the compound’s electron-withdrawing characteristics make it a candidate for designing organic semiconductors, a field gaining traction due to the push for flexible and lightweight electronic devices.

From a medicinal chemistry perspective, 1-Methyl-3-(3-nitro-phenyl)-1H-pyrazole is often discussed in forums and research papers for its scaffold’s resemblance to known kinase inhibitors. Kinases are critical targets in cancer therapy, and the search for "pyrazole-based kinase inhibitors" has risen exponentially. The nitro group in this compound can be reduced to an amine, offering a pathway to derivatize the molecule for enhanced bioactivity. This adaptability is crucial for structure-activity relationship (SAR) studies, a trending focus in drug development.

In the realm of agrochemicals, 886851-64-5 is explored for its potential as a precursor to pesticides and herbicides. The pyrazole ring is a common motif in agrochemicals due to its stability and ability to disrupt pest metabolic pathways. Queries like "nitro-phenyl pyrazole agrochemical uses" highlight the agricultural sector’s interest in sustainable pest control solutions. The compound’s lipophilic nature also makes it a candidate for formulating controlled-release agrochemicals, addressing environmental concerns about over-application.

Analytical techniques for characterizing 1-Methyl-3-(3-nitro-phenyl)-1H-pyrazole are another area of interest. High-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) are frequently used to verify its purity and structure. Searches for "CAS 886851-64-5 analysis methods" reflect the need for reliable quality control in industrial and academic settings. The compound’s UV-Vis absorption properties are also studied for applications in sensors and dyes, linking to the broader theme of functional materials.

In summary, 1-Methyl-3-(3-nitro-phenyl)-1H-pyrazole (CAS No. 886851-64-5) is a multifaceted compound with applications spanning pharmaceuticals, materials, and agrochemicals. Its pyrazole core and nitro-phenyl group make it a valuable entity in synthetic chemistry, while ongoing research continues to uncover new potentials. As interest in sustainable synthesis and targeted drug design grows, this compound remains a focal point for innovation across multiple scientific disciplines.

• 20583-31-7(3-(4-Nitrophenyl)-1H-pyrazole)
• 63500-30-1(1H-Pyrazole, 1-methyl-5-(4-nitrophenyl)-3-phenyl-)
• 63500-31-2(1H-Pyrazole, 1-methyl-3-(4-nitrophenyl)-5-phenyl-)
• 63532-66-1(3-(4-nitrophenyl)-5-phenyl-1H-pyrazole)
• 20147-63-1(1H-Pyrazole, 3-(4-nitrophenyl)-1-phenyl-)
• 59548-24-2(3,5-Bis(4-nitrophenyl)-1H-pyrazole)
• 942920-34-5(1-Tert-butyl-3-(4-nitrophenyl)-1H-pyrazole)
• 669714-81-2(1H-Pyrazole, 3-(4-nitrophenyl)-1,5-diphenyl-)
• 59843-77-5(3-(3-Nitrophenyl)-1H-pyrazole)
• 73387-59-4(1-Methyl-3-(4-nitro-phenyl)-1H-pyrazole)