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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Dimethoxybenzenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Methoxybenzenes Dimethoxybenzenes

Comprehensive Overview of 2,6-Dimethoxybenzene-1-carboximidamide (CAS No. 885957-17-5): Properties, Applications, and Research Insights

2,6-Dimethoxybenzene-1-carboximidamide (CAS No. 885957-17-5) is a specialized organic compound belonging to the class of benzene derivatives with significant potential in pharmaceutical and agrochemical research. This compound, characterized by its dimethoxy and carboximidamide functional groups, has garnered attention for its unique structural properties and versatile reactivity. Researchers and industries are increasingly exploring its applications in drug discovery, catalysis, and material science, aligning with current trends in sustainable chemistry and precision synthesis.

The molecular structure of 2,6-dimethoxybenzene-1-carboximidamide features two methoxy groups (–OCH₃) at the 2- and 6-positions of the benzene ring, coupled with a carboximidamide (–C(=NH)NH₂) moiety at the 1-position. This arrangement imparts distinct electronic and steric effects, making it a valuable intermediate for constructing heterocyclic compounds and bioactive molecules. Recent studies highlight its role in the synthesis of kinase inhibitors and antimicrobial agents, addressing growing demands for novel therapeutics in global health.

In the context of green chemistry, 885957-17-5 exemplifies advancements in atom-efficient synthesis. Its derivatives are being investigated for catalytic applications in cross-coupling reactions, a hot topic in organic synthesis. The compound’s stability under mild conditions aligns with industry priorities for low-energy processes and reduced waste generation, resonating with ESG (Environmental, Social, and Governance) metrics in chemical manufacturing.

From a commercial perspective, suppliers of 2,6-dimethoxybenzene-1-carboximidamide emphasize its high purity (>98%) and compatibility with high-throughput screening platforms. This aligns with the pharmaceutical industry’s shift toward fragment-based drug design (FBDD), where small-molecule building blocks like this compound accelerate lead optimization. Analytical techniques such as HPLC and NMR spectroscopy are routinely employed to validate its quality, ensuring reproducibility in research.

Emerging discussions in AI-driven drug discovery further highlight the relevance of CAS 885957-17-5. Computational models frequently utilize such scaffolds to predict ADMET properties (Absorption, Distribution, Metabolism, Excretion, and Toxicity), addressing frequent user queries about compound druggability. The compound’s balanced lipophilicity (LogP ~1.5) and hydrogen-bonding capacity make it a candidate for blood-brain barrier penetration studies—a trending subtopic in neurodegenerative disease research.

Regulatory and safety profiles of 2,6-dimethoxybenzene carboximidamide are well-documented, with no significant hazards under standard handling protocols. Its non-toxic degradation products support its inclusion in benign-by-design initiatives, a key focus area for regulatory bodies like the EPA and REACH. This positions the compound favorably for industrial-scale applications without restrictive compliance burdens.

In summary, 2,6-dimethoxybenzene-1-carboximidamide (CAS No. 885957-17-5) represents a convergence of synthetic utility, therapeutic potential, and environmental compatibility. As research continues to uncover its broader applications—from photocatalysis to bioconjugation—this compound is poised to remain a focal point in cutting-edge chemical innovation.

• 32048-19-4(2,4-dimethoxybenzene-1-carboximidamide)
• 131947-81-4(2,4-Dimethoxy-benzamidine hydrochloride)
• 885954-26-7(2,3,4-TRIMETHOXY-BENZAMIDINE)
• 160150-35-6(2,4,6-trimethoxybenzene-1-carboximidamide)
• 885270-13-3(2-methoxynaphthalene-1-carboximidamide)
• 126007-97-4(4-methoxy-3-methylbenzene-1-carboximidamide)
• 53623-81-7(2-ethoxybenzene-1-carboximidamide)
• 51818-19-0(2-Methoxybenzamidine hydrochloride)
• 89446-96-8(Benzenecarboximidamide, 4,4'-oxybis[3-methyl-, dihydrochloride (9CI))
• 57075-83-9(2-Methoxy-benzamidine Hydrochloride)