• 1. Excimer–monomer switch: a reaction-based approach for selective detection of fluoride?
  Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
• 2. Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330
  Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
• 3. Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation
  Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
• 4. Estimation of fusel-oil in spirits
  Analyst, 1890,15, 203-209
• 5. Exclusive self-aligned β-phase PVDF films with abnormal piezoelectric coefficient prepared via phase inversion?
  N. Soin,D. Boyer,K. Prashanthi,S. Sharma,A. A. Narasimulu,J. Luo,T. H. Shah,E. Siores,T. Thundat Chem. Commun., 2015,51, 8257-8260

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Dimethoxybenzenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Methoxybenzenes Dimethoxybenzenes

Recent Advances in the Study of 2,4-Dimethoxy-benzamidine Hydrochloride (CAS: 131947-81-4)

2,4-Dimethoxy-benzamidine hydrochloride (CAS: 131947-81-4) is a chemical compound of significant interest in the field of chemical biology and pharmaceutical research. This compound, known for its amidine functional group and dimethoxy substitutions, has been the subject of recent studies due to its potential applications in drug development and biochemical research. The unique structural features of this molecule make it a valuable candidate for investigating enzyme inhibition, receptor binding, and other pharmacological activities.

Recent research has focused on the synthesis and characterization of 2,4-dimethoxy-benzamidine hydrochloride, aiming to optimize its yield and purity for further applications. Advanced analytical techniques such as NMR spectroscopy, mass spectrometry, and X-ray crystallography have been employed to confirm its molecular structure and stability. These studies have provided critical insights into the compound's physicochemical properties, which are essential for its potential use in medicinal chemistry.

One of the key areas of investigation involves the role of 2,4-dimethoxy-benzamidine hydrochloride as a protease inhibitor. Preliminary in vitro studies have demonstrated its ability to inhibit specific serine proteases, which are implicated in various pathological conditions, including inflammatory diseases and cancer. The compound's mechanism of action appears to involve competitive binding to the active site of the target enzymes, thereby blocking their catalytic activity. These findings suggest that 2,4-dimethoxy-benzamidine hydrochloride could serve as a lead compound for the development of novel therapeutic agents.

In addition to its protease inhibition properties, recent studies have explored the compound's potential as a building block for the synthesis of more complex molecules. Researchers have successfully utilized 2,4-dimethoxy-benzamidine hydrochloride in the preparation of heterocyclic compounds, which are known for their diverse biological activities. This synthetic versatility highlights the compound's importance in the design and development of new chemical entities for drug discovery.

Despite these promising findings, further research is needed to fully elucidate the pharmacological profile of 2,4-dimethoxy-benzamidine hydrochloride. Future studies should focus on in vivo evaluations to assess its bioavailability, pharmacokinetics, and potential toxicity. Additionally, structure-activity relationship (SAR) studies could help optimize its biological activity and selectivity, paving the way for the development of more potent and specific inhibitors.

In conclusion, 2,4-dimethoxy-benzamidine hydrochloride (CAS: 131947-81-4) represents a promising compound with significant potential in chemical biology and pharmaceutical research. Its unique structural features and demonstrated biological activities make it a valuable tool for understanding enzyme mechanisms and developing new therapeutic agents. Continued research efforts will be essential to unlock its full potential and translate these findings into clinical applications.

• 18637-00-8(2-Ethoxybenzamidine Hydrochloride)
• 32048-19-4(2,4-dimethoxybenzene-1-carboximidamide)
• 885957-17-5(2,6-dimethoxybenzene-1-carboximidamide)
• 885954-26-7(2,3,4-TRIMETHOXY-BENZAMIDINE)
• 160150-35-6(2,4,6-trimethoxybenzene-1-carboximidamide)
• 885270-13-3(2-methoxynaphthalene-1-carboximidamide)
• 126007-97-4(4-methoxy-3-methylbenzene-1-carboximidamide)
• 51818-19-0(2-Methoxybenzamidine hydrochloride)
• 89446-96-8(Benzenecarboximidamide, 4,4'-oxybis[3-methyl-, dihydrochloride (9CI))
• 57075-83-9(2-Methoxy-benzamidine Hydrochloride)